DE3688632T2 - Process for the preparation of solid phase peptides. - Google Patents

Process for the preparation of solid phase peptides.

Info

Publication number
DE3688632T2
DE3688632T2 DE86302731T DE3688632T DE3688632T2 DE 3688632 T2 DE3688632 T2 DE 3688632T2 DE 86302731 T DE86302731 T DE 86302731T DE 3688632 T DE3688632 T DE 3688632T DE 3688632 T2 DE3688632 T2 DE 3688632T2
Authority
DE
Germany
Prior art keywords
preparation
solid phase
phase peptides
peptides
solid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE86302731T
Other languages
German (de)
Other versions
DE3688632D1 (en
Inventor
Su Sun Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alpha 1 Biomedicals Inc
Original Assignee
Alpha 1 Biomedicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alpha 1 Biomedicals Inc filed Critical Alpha 1 Biomedicals Inc
Publication of DE3688632D1 publication Critical patent/DE3688632D1/en
Application granted granted Critical
Publication of DE3688632T2 publication Critical patent/DE3688632T2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57581—Thymosin; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/18—Thymus derived hormone or factor; related peptides
DE86302731T 1985-04-11 1986-04-11 Process for the preparation of solid phase peptides. Expired - Lifetime DE3688632T2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72221885A 1985-04-11 1985-04-11
US06/849,835 US4855407A (en) 1985-04-11 1986-04-09 Solid phase process for synthesizing peptides

Publications (2)

Publication Number Publication Date
DE3688632D1 DE3688632D1 (en) 1993-08-05
DE3688632T2 true DE3688632T2 (en) 1993-10-07

Family

ID=27110560

Family Applications (1)

Application Number Title Priority Date Filing Date
DE86302731T Expired - Lifetime DE3688632T2 (en) 1985-04-11 1986-04-11 Process for the preparation of solid phase peptides.

Country Status (5)

Country Link
US (1) US4855407A (en)
EP (1) EP0200404B1 (en)
JP (2) JP2733591B2 (en)
DE (1) DE3688632T2 (en)
HK (1) HK1097A (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4831084A (en) * 1987-05-18 1989-05-16 Bachem Feinchemikalien A.G. Resin-linker combination for the solid-phase synthesis of peptides and intermediates
GB8807427D0 (en) * 1988-03-28 1988-05-05 National Biological Standards Board Peptides
EP0341935B1 (en) * 1988-05-10 1996-04-10 Alpha-1 Biomedicals, Inc. A solid phase process for synthesizing Thymosin alpha 1
US5212288A (en) * 1990-02-20 1993-05-18 Syntex (U.S.A.) Inc. Temporary minimal protection synthesis of serine-containing polypeptides
US5308833A (en) * 1992-02-06 1994-05-03 Sciclone Pharmaceuticals Method for treating hepatitis B carriers with minimal disease
CN1058500C (en) * 1993-02-03 2000-11-15 施塞克龙药品公司 Thymosin alpha-1 derivatives
US6200952B1 (en) 1993-06-02 2001-03-13 Sciclone Pharmaceuticals, Inc. Combination therapy method for treating chronic hepatitis B
US6262230B1 (en) * 1994-01-28 2001-07-17 Sciclone Pharmaceuticals Inc. Analogs of thymosin α1
US5817758A (en) * 1995-06-07 1998-10-06 Terrapin Technologies, Inc. P-nitrobenzyl side-chain protection for solid-phase synthesis
WO2001096527A2 (en) * 2000-06-14 2001-12-20 Chanda Zaveri Peptides with physiological activity
GB0710529D0 (en) 2007-06-01 2007-07-11 Circassia Ltd Vaccine
GB0821806D0 (en) 2008-11-28 2009-01-07 Circassia Ltd Compositions with reduced dimer formation
JP6734258B2 (en) * 2015-03-04 2020-08-05 栄研化学株式会社 Highly sensitive assay for oxytocin
CN108218980B (en) * 2016-12-21 2020-12-08 鲁南制药集团股份有限公司 Synthesis method of thymalfasin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3714140A (en) * 1971-03-16 1973-01-30 Squibb & Sons Inc Peptide synthesis
US4207311A (en) * 1977-07-18 1980-06-10 The Salk Institute For Biological Studies Peptides having analgesic and thermoregulative properties
US4148788A (en) * 1978-01-23 1979-04-10 Hoffmann-La Roche Inc. Synthesis of thymosin α1
JPS54148722A (en) * 1978-05-12 1979-11-21 Takeda Chem Ind Ltd Nonapeptide and its preparation
US4244946A (en) * 1979-06-11 1981-01-13 The Salk Institute For Biological Studies Water-soluble peptides affecting gonadal function
US4382922A (en) * 1980-08-29 1983-05-10 The Salk Institute For Biological Studies Peptides affecting gonadal function
US4406832A (en) * 1981-09-03 1983-09-27 Mallinckrodt, Inc. Peptide-type substrates useful in the quantitative determination of endotoxin
US4507230A (en) * 1982-05-12 1985-03-26 Research Corporation Peptide synthesis reagents and method of use
US4478984A (en) * 1983-09-23 1984-10-23 Smithkline Beckman Corporation Synthesis of benzhydrylamine resins

Also Published As

Publication number Publication date
DE3688632D1 (en) 1993-08-05
JPH10152500A (en) 1998-06-09
EP0200404B1 (en) 1993-06-30
HK1097A (en) 1997-01-10
JPS61289097A (en) 1986-12-19
US4855407A (en) 1989-08-08
JP2925523B2 (en) 1999-07-28
JP2733591B2 (en) 1998-03-30
EP0200404A3 (en) 1988-08-31
EP0200404A2 (en) 1986-11-05

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Legal Events

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8364 No opposition during term of opposition