DE3684474D1 - Verwendung von cobalt proto-und mesoporphyrin zur herstellungeines arzneimittels zur hemmung des endocrinen systems. - Google Patents
Verwendung von cobalt proto-und mesoporphyrin zur herstellungeines arzneimittels zur hemmung des endocrinen systems.Info
- Publication number
- DE3684474D1 DE3684474D1 DE8787900460T DE3684474T DE3684474D1 DE 3684474 D1 DE3684474 D1 DE 3684474D1 DE 8787900460 T DE8787900460 T DE 8787900460T DE 3684474 T DE3684474 T DE 3684474T DE 3684474 D1 DE3684474 D1 DE 3684474D1
- Authority
- DE
- Germany
- Prior art keywords
- mesoporphyrin
- proto
- cobalt
- inhibiting
- producing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000000750 endocrine system Anatomy 0.000 title abstract 2
- NCAJWYASAWUEBY-UHFFFAOYSA-N 3-[20-(2-carboxyethyl)-9,14-diethyl-5,10,15,19-tetramethyl-21,22,23,24-tetraazapentacyclo[16.2.1.1^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1(21),2,4,6(24),7,9,11,13,15,17,19-undecaen-4-yl]propanoic acid Chemical compound N1C2=C(C)C(CC)=C1C=C(N1)C(C)=C(CC)C1=CC(C(C)=C1CCC(O)=O)=NC1=CC(C(CCC(O)=O)=C1C)=NC1=C2 NCAJWYASAWUEBY-UHFFFAOYSA-N 0.000 title 1
- 229910017052 cobalt Inorganic materials 0.000 title 1
- 239000010941 cobalt Substances 0.000 title 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Studio Devices (AREA)
- Vehicle Body Suspensions (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83251286A | 1986-02-21 | 1986-02-21 | |
US92783086A | 1986-11-06 | 1986-11-06 | |
PCT/US1986/002600 WO1987004927A1 (en) | 1986-02-21 | 1986-12-03 | Methods for suppressing the endocrine system |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3684474D1 true DE3684474D1 (de) | 1992-04-23 |
Family
ID=27125543
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8787900460T Expired - Lifetime DE3684474D1 (de) | 1986-02-21 | 1986-12-03 | Verwendung von cobalt proto-und mesoporphyrin zur herstellungeines arzneimittels zur hemmung des endocrinen systems. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0259353B1 (de) |
AT (1) | ATE73659T1 (de) |
AU (2) | AU6839687A (de) |
DE (1) | DE3684474D1 (de) |
WO (1) | WO1987004927A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4997828A (en) * | 1989-02-14 | 1991-03-05 | The Rockefeller University | Method of weight control by low level administration of cobalt protoporphyrin or cobalt mesoporphyrin |
US5192757A (en) * | 1990-12-20 | 1993-03-09 | Glaxo Inc. | Cobalt porphyrins |
US5149697A (en) * | 1991-04-18 | 1992-09-22 | Glaxo Inc. | Cobalt porphyrin pharmaceutical compositions |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4393071A (en) * | 1975-03-17 | 1983-07-12 | Naoharu Fujii | Method of treating gastric, mammary, lung and uterus tumors |
-
1986
- 1986-12-03 AT AT87900460T patent/ATE73659T1/de not_active IP Right Cessation
- 1986-12-03 AU AU68396/87A patent/AU6839687A/en not_active Withdrawn
- 1986-12-03 DE DE8787900460T patent/DE3684474D1/de not_active Expired - Lifetime
- 1986-12-03 WO PCT/US1986/002600 patent/WO1987004927A1/en active IP Right Grant
- 1986-12-03 EP EP87900460A patent/EP0259353B1/de not_active Expired
-
1988
- 1988-01-15 AU AU10333/88A patent/AU598898B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
AU1033388A (en) | 1988-05-05 |
AU6839687A (en) | 1987-09-09 |
AU598898B2 (en) | 1990-07-05 |
EP0259353A4 (de) | 1990-02-05 |
EP0259353B1 (de) | 1992-03-18 |
EP0259353A1 (de) | 1988-03-16 |
WO1987004927A1 (en) | 1987-08-27 |
ATE73659T1 (de) | 1992-04-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |