DE3661538D1 - Novel disaccharide and trisaccharide derivatives of the "lipid a" type - Google Patents
Novel disaccharide and trisaccharide derivatives of the "lipid a" typeInfo
- Publication number
- DE3661538D1 DE3661538D1 DE8686200193T DE3661538T DE3661538D1 DE 3661538 D1 DE3661538 D1 DE 3661538D1 DE 8686200193 T DE8686200193 T DE 8686200193T DE 3661538 T DE3661538 T DE 3661538T DE 3661538 D1 DE3661538 D1 DE 3661538D1
- Authority
- DE
- Germany
- Prior art keywords
- lipid
- type
- novel disaccharide
- trisaccharide derivatives
- trisaccharide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL8500499 | 1985-02-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3661538D1 true DE3661538D1 (en) | 1989-02-02 |
Family
ID=19845570
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686200193T Expired DE3661538D1 (en) | 1985-02-22 | 1986-02-12 | Novel disaccharide and trisaccharide derivatives of the "lipid a" type |
Country Status (13)
Country | Link |
---|---|
US (1) | US4719202A (de) |
EP (1) | EP0192296B1 (de) |
JP (1) | JPS61246195A (de) |
KR (1) | KR860006479A (de) |
AU (1) | AU583093B2 (de) |
CA (1) | CA1259308A (de) |
DE (1) | DE3661538D1 (de) |
DK (1) | DK83386A (de) |
ES (1) | ES8707967A1 (de) |
FI (1) | FI860747A (de) |
GR (1) | GR860379B (de) |
PT (1) | PT82067B (de) |
ZA (1) | ZA861013B (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU199494B (en) * | 1985-06-28 | 1990-02-28 | Sandoz Ag | Process for producing new saccharides and pharmaceutical compositions comprising same |
DE3604681A1 (de) * | 1986-02-14 | 1987-08-20 | Bayer Ag | Neue n-glycosylamidderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
US4929604A (en) * | 1986-05-28 | 1990-05-29 | Board Of Regents, The University Of Texas System | Lipopolysaccharides of reduced toxicity and the production thereof |
EP0333243A3 (de) * | 1988-03-10 | 1989-09-27 | Akzo N.V. | Sulphatiertes K5-Antigen und seine Fragmente |
IT1229514B (it) * | 1989-01-30 | 1991-09-03 | Farmhispania S A A Montme | Glicoconiugati anfifilici sintetici per impiego neurologico. |
JPH0655749B2 (ja) * | 1989-09-20 | 1994-07-27 | 日本たばこ産業株式会社 | リピッドa単糖類縁体 |
CA2045550A1 (en) * | 1989-11-09 | 1991-05-10 | Koichiro Miyajima | Glucosamine derivative and liposome containing the same as membrane constituent |
KR940000166B1 (ko) * | 1989-11-09 | 1994-01-08 | 니혼다바고 상교오 가부시기가이샤 | 신규 글루코사민 유도체 및 이것을 막 구성성분으로서 함유한 리포솜 |
EP0482206A4 (en) * | 1990-04-12 | 1992-08-19 | Japan Tobacco Inc. | 4,6-o-hydroxyphosphorylglucosamine derivative |
US5158941A (en) * | 1990-06-08 | 1992-10-27 | E. I. Du Pont De Nemours And Company | Lipid A analog as stimulant for production of interleukin-1 in human monocytes and tumor cell growth inhibitor |
DK0729473T3 (da) * | 1993-11-17 | 2000-10-30 | Deutsche Om Arzneimittel Gmbh | Glucosamin-disaccharider, fremgangsmåde til deres fremstilling farmaceutisk sammensætning deraf og deres anvendelse |
US5648343A (en) * | 1994-02-28 | 1997-07-15 | The University Of Georgia Research Foundation | Method for treating LPS-mediated disorders |
FR2751876B1 (fr) * | 1996-07-31 | 1998-12-31 | Roc Sa | Utilisation d'un oligosaccharide comme immunomodulateur, composition dermato-cosmetique et methode de traitement cosmetique |
EP1104767A1 (de) † | 1999-11-30 | 2001-06-06 | Stichting Dienst Landbouwkundig Onderzoek | Mono- und Disaccharidederivate die sowohl Fettsäureestern als Sulfatestern enthalten |
FR2804684B1 (fr) * | 2000-02-04 | 2002-06-28 | Goemar Lab Sa | Procede pour la preparation de derives fonctionnalises de beta-(1,3)-glucanes |
CN100335795C (zh) * | 2002-05-07 | 2007-09-05 | Emu潜水泵有限公司 | 尤其适用于泵的电机 |
EP1549322B1 (de) | 2002-05-09 | 2010-02-17 | Oncothyreon Inc. | Lipid-a- und andere kohlenhydrat-liganden-analoga |
AU2003289493A1 (en) * | 2002-12-24 | 2004-07-22 | Mochizuki, Takashi | Lipid a analogues having glucose as the right sugar |
AU2012222188A1 (en) | 2011-02-24 | 2013-08-15 | Oncothyreon Inc. | MUC1 based glycolipopeptide vaccine with adjuvant |
US9241988B2 (en) * | 2012-04-12 | 2016-01-26 | Avanti Polar Lipids, Inc. | Disaccharide synthetic lipid compounds and uses thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2477551A1 (fr) * | 1980-03-10 | 1981-09-11 | Anvar | Nouveaux derives de l'a, a'-trehalose et medicaments les contenant |
AU561066B2 (en) * | 1982-03-22 | 1987-04-30 | Biocarb Ab | Antibacterial composition containing an oligosaccharide |
US4515782A (en) * | 1983-08-29 | 1985-05-07 | American Cyanamid Company | Substituted phenyl-1-thio(poly-O-sulfo)-α(or β)-D-glucopyranosides |
-
1986
- 1986-02-10 GR GR860379A patent/GR860379B/el unknown
- 1986-02-11 ZA ZA861013A patent/ZA861013B/xx unknown
- 1986-02-11 US US06/828,277 patent/US4719202A/en not_active Expired - Fee Related
- 1986-02-12 EP EP86200193A patent/EP0192296B1/de not_active Expired
- 1986-02-12 DE DE8686200193T patent/DE3661538D1/de not_active Expired
- 1986-02-14 AU AU53488/86A patent/AU583093B2/en not_active Ceased
- 1986-02-17 CA CA000502033A patent/CA1259308A/en not_active Expired
- 1986-02-20 JP JP61036492A patent/JPS61246195A/ja active Pending
- 1986-02-20 FI FI860747A patent/FI860747A/fi not_active Application Discontinuation
- 1986-02-21 DK DK83386A patent/DK83386A/da not_active Application Discontinuation
- 1986-02-21 ES ES552297A patent/ES8707967A1/es not_active Expired
- 1986-02-21 PT PT82067A patent/PT82067B/pt unknown
- 1986-02-21 KR KR1019860001285A patent/KR860006479A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ZA861013B (en) | 1986-09-24 |
DK83386D0 (da) | 1986-02-21 |
AU583093B2 (en) | 1989-04-20 |
ES552297A0 (es) | 1987-09-01 |
KR860006479A (ko) | 1986-09-11 |
EP0192296A1 (de) | 1986-08-27 |
PT82067A (en) | 1986-03-01 |
ES8707967A1 (es) | 1987-09-01 |
FI860747A (fi) | 1986-08-23 |
EP0192296B1 (de) | 1988-12-28 |
CA1259308A (en) | 1989-09-12 |
AU5348886A (en) | 1986-08-28 |
JPS61246195A (ja) | 1986-11-01 |
FI860747A0 (fi) | 1986-02-20 |
DK83386A (da) | 1986-08-23 |
US4719202A (en) | 1988-01-12 |
GR860379B (en) | 1986-06-11 |
PT82067B (en) | 1987-07-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |