DE3650368T2 - Use of Depogen to treat restricted blood circulation. - Google Patents

Use of Depogen to treat restricted blood circulation.

Info

Publication number
DE3650368T2
DE3650368T2 DE3650368T DE3650368T DE3650368T2 DE 3650368 T2 DE3650368 T2 DE 3650368T2 DE 3650368 T DE3650368 T DE 3650368T DE 3650368 T DE3650368 T DE 3650368T DE 3650368 T2 DE3650368 T2 DE 3650368T2
Authority
DE
Germany
Prior art keywords
depogen
blood circulation
diethoxy
restricted blood
treat
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3650368T
Other languages
German (de)
Other versions
DE3650368D1 (en
Inventor
Peter Szentmiklosi
Istvan Hermecz
Zoltan Meszaros
Laszlo Tardos
Jeno Marton
Lelle Vasvari
Agnes Horvarth
Katalin Marmarosi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Application granted granted Critical
Publication of DE3650368D1 publication Critical patent/DE3650368D1/en
Publication of DE3650368T2 publication Critical patent/DE3650368T2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

The use of 1-(3',4'-diethoxybenzyl)-6,7-diethoxy-3,4-dihydroisoquinolinium-theophyl line-7-acetate (Depogen) for the manufacture of a medicament for use in the treatment of conditions resulting from restricted circulation of the blood in the smaller blood vessels by administration of an amount providing a drug blood concentration of 0.5 to 3 g<-><6>/ml calculated on the 1-(3',4'-diethoxy-benzyl)-6,7-diethoxy-3,4-dihydroisoquinoline.
DE3650368T 1985-12-04 1986-12-04 Use of Depogen to treat restricted blood circulation. Expired - Fee Related DE3650368T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU854639A HU197207B (en) 1985-12-04 1985-12-04 Process for producing pharmaceutical comprising 1-(3',4'-diethoxybenzyl)-6,7-diethoxy-3,4-dihydro-isoquinolinium-theophylline-7-acetate or its monohydrate as active ingredient

Publications (2)

Publication Number Publication Date
DE3650368D1 DE3650368D1 (en) 1995-09-21
DE3650368T2 true DE3650368T2 (en) 1996-01-18

Family

ID=10968537

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3650368T Expired - Fee Related DE3650368T2 (en) 1985-12-04 1986-12-04 Use of Depogen to treat restricted blood circulation.

Country Status (6)

Country Link
US (1) US4814336A (en)
EP (1) EP0227356B1 (en)
JP (1) JPH0655672B2 (en)
AT (1) ATE126437T1 (en)
DE (1) DE3650368T2 (en)
HU (1) HU197207B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT60926A (en) * 1991-04-12 1992-11-30 Chinoin Gyogyszer Es Vegyeszet Process for producing pharmaceutical composition suitable for reducing or preventing increased thrombocyte-aggregation capability
HUT68560A (en) * 1993-08-02 1995-04-27 Chinoin Gyogyszer Es Vegyeszet The use of xantine derivatives for promotion of healing of operative lesions
JP3276762B2 (en) * 1993-12-28 2002-04-22 日本臓器製薬株式会社 Pharmaceutical composition containing isoquinoline derivative
AU2009319348B2 (en) * 2008-11-27 2014-07-31 Lidds Ab Use of carboxymethylcellulose to control ejectability and solidification of time of compositions one or more bioresorbable ceramics
MX354485B (en) * 2011-05-20 2018-03-07 Chinoin Private Co Ltd Pharmaceutical composition comprising drotaverine.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1129134A (en) * 1964-11-04 1968-10-02 Sterling Winthrop Group Ltd Improvements in compositions containing nicotinates
FR4135M (en) * 1965-01-19 1966-05-02
DE1492203A1 (en) * 1965-12-29 1970-01-15 Thomae Gmbh Dr K Process for the preparation of stable solutions of theophylline
FR2181717B1 (en) * 1968-11-25 1976-11-05 Albert Ag Chem Werke
FR2202686A1 (en) * 1972-10-13 1974-05-10 Fabre Sa Pierre Nicotinyl theophylline acetate hydrochloride - ingredient in medicaments for circulatory disorders and dyslipemia
HU167246B (en) * 1973-01-25 1975-09-27
FR2279394A2 (en) * 1973-12-13 1976-02-20 Saunier Laboratoires Cerebral vasodilator compsns - of vincamine, ascorbic acid and papaverine hydrochloride for oral and parenteral admin
US4364922A (en) * 1980-10-14 1982-12-21 University Of Virginia Alumni Patents Foundation Adenosine antagonists in the treatment and diagnosis of A-V node conduction disturbances
US4383997A (en) * 1980-11-26 1983-05-17 Boucher John H Method of treating horses to inhibit or reduce increases in crenated red blood cells during exercise

Also Published As

Publication number Publication date
US4814336A (en) 1989-03-21
ATE126437T1 (en) 1995-09-15
EP0227356A2 (en) 1987-07-01
HU197207B (en) 1989-03-28
DE3650368D1 (en) 1995-09-21
JPH0655672B2 (en) 1994-07-27
EP0227356B1 (en) 1995-08-16
HUT42940A (en) 1987-09-28
EP0227356A3 (en) 1989-12-13
JPS62187411A (en) 1987-08-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee