DE3580619D1 - Optische vorrichtung mit hoher sammelwirkung und zytofluorimeter mit verwendung der vorrichtung. - Google Patents

Optische vorrichtung mit hoher sammelwirkung und zytofluorimeter mit verwendung der vorrichtung.

Info

Publication number
DE3580619D1
DE3580619D1 DE8585401188T DE3580619T DE3580619D1 DE 3580619 D1 DE3580619 D1 DE 3580619D1 DE 8585401188 T DE8585401188 T DE 8585401188T DE 3580619 T DE3580619 T DE 3580619T DE 3580619 D1 DE3580619 D1 DE 3580619D1
Authority
DE
Germany
Prior art keywords
cytofluorimeter
collectible
optical device
optical
high collectible
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585401188T
Other languages
English (en)
Inventor
Jean-Claude Gaucher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA filed Critical Commissariat a lEnergie Atomique CEA
Application granted granted Critical
Publication of DE3580619D1 publication Critical patent/DE3580619D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B19/00Condensers, e.g. light collectors or similar non-imaging optics
    • G02B19/0004Condensers, e.g. light collectors or similar non-imaging optics characterised by the optical means employed
    • G02B19/0028Condensers, e.g. light collectors or similar non-imaging optics characterised by the optical means employed refractive and reflective surfaces, e.g. non-imaging catadioptric systems
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B19/00Condensers, e.g. light collectors or similar non-imaging optics
    • G02B19/0033Condensers, e.g. light collectors or similar non-imaging optics characterised by the use
    • G02B19/0047Condensers, e.g. light collectors or similar non-imaging optics characterised by the use for use with a light source
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B19/00Condensers, e.g. light collectors or similar non-imaging optics
    • G02B19/0033Condensers, e.g. light collectors or similar non-imaging optics characterised by the use
    • G02B19/0095Condensers, e.g. light collectors or similar non-imaging optics characterised by the use for use with ultraviolet radiation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • G01N15/1436Optical arrangements the optical arrangement forming an integrated apparatus with the sample container, e.g. a flow cell
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/149Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1019Associating Coulter-counter and optical flow cytometer [OFC]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1024Counting particles by non-optical means

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Measuring Cells (AREA)
DE8585401188T 1984-06-20 1985-06-14 Optische vorrichtung mit hoher sammelwirkung und zytofluorimeter mit verwendung der vorrichtung. Expired - Lifetime DE3580619D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8409676A FR2566543B1 (fr) 1984-06-20 1984-06-20 Dispositif optique a rendement de collection eleve et cytofluorimetre en faisant application

Publications (1)

Publication Number Publication Date
DE3580619D1 true DE3580619D1 (de) 1991-01-03

Family

ID=9305236

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585401188T Expired - Lifetime DE3580619D1 (de) 1984-06-20 1985-06-14 Optische vorrichtung mit hoher sammelwirkung und zytofluorimeter mit verwendung der vorrichtung.

Country Status (6)

Country Link
US (1) US4673289A (de)
EP (1) EP0165868B1 (de)
JP (1) JPS6113139A (de)
DE (1) DE3580619D1 (de)
FR (1) FR2566543B1 (de)
IL (1) IL75537A0 (de)

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FR2621123B1 (fr) * 1987-09-30 1989-12-01 Commissariat Energie Atomique Procede de fabrication d'un dispositif d'analyse optique d'un flux de microparticules et application a la fabrication d'un cytofluorimetre
JP2635992B2 (ja) * 1988-03-24 1997-07-30 興和株式会社 微粒子測定装置
FR2653885B1 (fr) * 1989-10-27 1994-01-14 Abx Appareil pour le comptage et la determination d'au moins une sous-population leucocytaire.
DE4030699C1 (de) * 1990-09-28 1991-10-10 Bruker Analytische Messtechnik Gmbh, 7512 Rheinstetten, De
FR2667689B1 (fr) * 1990-10-04 1994-08-05 Saint Gobain Isover Mesure du debit d'un filet de materiau fondu.
JP3212647B2 (ja) * 1991-10-24 2001-09-25 シスメックス株式会社 イメージングフローサイトメータ
US5530540A (en) * 1994-08-03 1996-06-25 Wyatt Technology Corporation Light scattering measurement cell for very small volumes
ATE298084T1 (de) 1997-01-31 2005-07-15 Horticulture & Food Res Inst Optische vorrichtung und methode
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
CN1664562A (zh) * 1998-05-16 2005-09-07 阿普尔拉公司 用于监测dna聚合酶链反应的仪器
US6818437B1 (en) * 1998-05-16 2004-11-16 Applera Corporation Instrument for monitoring polymerase chain reaction of DNA
US7498164B2 (en) 1998-05-16 2009-03-03 Applied Biosystems, Llc Instrument for monitoring nucleic acid sequence amplification reaction
US7410793B2 (en) 1999-05-17 2008-08-12 Applera Corporation Optical instrument including excitation source
US7423750B2 (en) * 2001-11-29 2008-09-09 Applera Corporation Configurations, systems, and methods for optical scanning with at least one first relative angular motion and at least one second angular motion or at least one linear motion
US20050279949A1 (en) 1999-05-17 2005-12-22 Applera Corporation Temperature control for light-emitting diode stabilization
US7387891B2 (en) * 1999-05-17 2008-06-17 Applera Corporation Optical instrument including excitation source
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
US7094527B2 (en) 2000-11-29 2006-08-22 Xy, Inc. System for in-vitro fertilization with spermatozoa separated into X-chromosome and Y-chromosome bearing populations
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US7635588B2 (en) * 2001-11-29 2009-12-22 Applied Biosystems, Llc Apparatus and method for differentiating multiple fluorescence signals by excitation wavelength
ATE537438T1 (de) * 2002-05-17 2011-12-15 Life Technologies Corp Vorrichtung und verfahren zur unterscheidung mehrerer fluoreszenzsignale anhand ihrer anregungswellenlänge
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
EP1545203B1 (de) 2002-08-01 2016-10-19 Xy, Llc Mit niederdruck arbeitendes spermazellentrennsystem
AU2003265471B2 (en) 2002-08-15 2009-08-06 Xy, Llc. High resolution flow cytometer
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
EP3511693B1 (de) 2003-03-28 2022-08-24 Inguran, LLC Vorrichtung zur anzeige des zerfallpunktes in einem tropfenerzeugungssystem
AU2004242121B2 (en) 2003-05-15 2010-06-24 Xy, Llc. Efficient haploid cell sorting for flow cytometer systems
US20050195604A1 (en) * 2004-03-05 2005-09-08 Saccomanno Robert J. Low cost fiber illuminator
US7151604B2 (en) * 2004-03-05 2006-12-19 Honeywell International Inc. Optical system and method for particle detection
WO2005095590A2 (en) 2004-03-29 2005-10-13 Monsanto Technology Llc Sperm suspensions for sorting into x or y chromosome-bearing enriched populations
CA2574499C (en) 2004-07-22 2016-11-29 Monsanto Technology Llc Process for enriching a population of sperm cells
FR2883973B1 (fr) * 2005-03-31 2007-11-16 C2 Diagnostics Sa Cuve pour dispositif optique d'analyse sanguine, appareil d'analyse equipe d'une telle cuve
US7982875B2 (en) * 2009-06-15 2011-07-19 Wyatt Technology Corporation Method and apparatus for measuring the scattered light signals from a liquid sample
CN110031384B (zh) * 2012-05-30 2023-03-10 艾瑞斯国际有限公司 流式细胞仪
US9746412B2 (en) 2012-05-30 2017-08-29 Iris International, Inc. Flow cytometer
JP6065527B2 (ja) * 2012-11-08 2017-01-25 ソニー株式会社 微小粒子分取装置及び微小粒子分取方法
FR3068469B1 (fr) * 2017-06-28 2020-09-11 Diagdev Cuve de mesure pour le denombrement et/ou la caracterisation de cellules
US11009452B2 (en) 2018-01-26 2021-05-18 Viavi Solutions Inc. Reduced false positive identification for spectroscopic quantification
US10810408B2 (en) 2018-01-26 2020-10-20 Viavi Solutions Inc. Reduced false positive identification for spectroscopic classification
US11656174B2 (en) 2018-01-26 2023-05-23 Viavi Solutions Inc. Outlier detection for spectroscopic classification
EP4022320A4 (de) * 2019-08-28 2022-11-02 Siemens Healthcare Diagnostics, Inc. Optische photometerkupplung für einen doppelten inkubationsring unter verwendung eines periskopdesigns

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US3788744A (en) * 1970-01-14 1974-01-29 Bio Physics Systems Inc Method and apparatus for photoanalysis
US3989381A (en) * 1975-05-05 1976-11-02 Coulter Electronics, Inc. Optical chamber with spherical reflective portion and apparatus employing same
DE2831926A1 (de) * 1978-07-20 1980-02-07 Hellmut Niethammmer Fa Kondensorsystem fuer einen grossbuehnen- projektionsapparat
US4348107A (en) * 1980-07-18 1982-09-07 Coulter Electronics, Inc. Orifice inside optical element
US4336029A (en) * 1980-08-15 1982-06-22 Ortho Diagnostic Systems Inc. Method and reagents for quantitative determination of reticulocytes and platelets in whole blood
GB2097144A (en) * 1981-03-23 1982-10-27 Tno New method for identifying algae in water samples and apparatus for use in that method
DE3266669D1 (en) * 1981-06-24 1985-11-07 Becton Dickinson Co Analyzer for simultaneously determining volume and light emission characteristics of particles
FR2531252B1 (fr) * 1982-07-29 1987-09-25 Guichard Jacques Procede d'affichage d'images en relief et dispositif de mise en oeuvre

Also Published As

Publication number Publication date
IL75537A0 (en) 1985-10-31
EP0165868A3 (en) 1987-04-22
FR2566543A1 (fr) 1985-12-27
US4673289A (en) 1987-06-16
FR2566543B1 (fr) 1988-02-26
JPS6113139A (ja) 1986-01-21
EP0165868B1 (de) 1990-11-22
EP0165868A2 (de) 1985-12-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee