DE3484244D1 - Herstellung von cdna die hepatitis a virale sequenzen darstellen. - Google Patents

Herstellung von cdna die hepatitis a virale sequenzen darstellen.

Info

Publication number
DE3484244D1
DE3484244D1 DE8484903735T DE3484244T DE3484244D1 DE 3484244 D1 DE3484244 D1 DE 3484244D1 DE 8484903735 T DE8484903735 T DE 8484903735T DE 3484244 T DE3484244 T DE 3484244T DE 3484244 D1 DE3484244 D1 DE 3484244D1
Authority
DE
Germany
Prior art keywords
hepatitis
cdna
represent
production
viral sequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8484903735T
Other languages
English (en)
Inventor
R Ticehurst
David Baltimore
M Feinstone
H Purcell
R Racaniello
M Baroudy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Application granted granted Critical
Publication of DE3484244D1 publication Critical patent/DE3484244D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/706Specific hybridization probes for hepatitis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32411Hepatovirus, i.e. hepatitis A virus
    • C12N2770/32422New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32411Hepatovirus, i.e. hepatitis A virus
    • C12N2770/32434Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
DE8484903735T 1983-09-30 1984-09-27 Herstellung von cdna die hepatitis a virale sequenzen darstellen. Expired - Fee Related DE3484244D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53791183A 1983-09-30 1983-09-30
PCT/US1984/001552 WO1985001517A1 (en) 1983-09-30 1984-09-27 PRODUCTION OF cDNA REPRESENTING HEPATITIS A VIRAL SEQUENCES

Publications (1)

Publication Number Publication Date
DE3484244D1 true DE3484244D1 (de) 1991-04-11

Family

ID=24144624

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484903735T Expired - Fee Related DE3484244D1 (de) 1983-09-30 1984-09-27 Herstellung von cdna die hepatitis a virale sequenzen darstellen.

Country Status (4)

Country Link
EP (1) EP0162054B1 (de)
JP (1) JPS61500053A (de)
DE (1) DE3484244D1 (de)
WO (1) WO1985001517A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3112338C2 (de) * 1981-03-28 1995-02-23 Klaus Von Der Helm Verwendung von Hybridisierungssonden zum Nachweis von HAV
EP0154587B1 (de) * 1984-03-02 1991-05-15 Merck & Co. Inc. DNS-Fragmente welche für Peptide kodieren, die fähig sind in vivo die Synthese von Antihepatitis-A-Virus-Antikörpern zu induzieren
CA1324094C (en) * 1985-04-03 1993-11-09 Dino Dina Hepatitis a virus vaccines
FR2623817B1 (fr) * 1987-11-26 1990-05-04 Pasteur Institut Sondes pour la detection d'enterovirus par hybridation moleculaire et pour la discrimination entre des poliovirus et d'autres enterovirus
US5789559A (en) * 1988-06-17 1998-08-04 Genelabs Technologies, Inc. DNA sequences of enterically transmitted non-A/non-B hepatitis viral agent
WO1989012641A1 (en) * 1988-06-17 1989-12-28 Genelabs Incorporated Enterically transmitted non-a/non-b hepatitis viral agent
US5824649A (en) * 1988-06-17 1998-10-20 Genelabs Technologies, Inc. DNA sequences of enterically transmitted non-A/non-B hepatitis viral agent and characteristic epitopes thereof
US5294548A (en) * 1990-04-02 1994-03-15 American Biogenetic Sciences, Inc Recombianant Hepatitis a virus
ATE400658T1 (de) * 1990-04-05 2008-07-15 Genelabs Tech Inc Enterisch übertragendes non-a/non-b-hepatitis- virus agens und charakteristische epitope von selbigem
ES2083152T3 (es) * 1990-11-30 1996-04-01 Monoclonetics Int Metodos para el diagnostico de dolores cronicos lumbares y cervicales.
HRP950097A2 (en) 1994-03-08 1997-06-30 Merck & Co Inc Hepatitis a virus culture process
US6280734B1 (en) * 1996-04-19 2001-08-28 The United States Of America As Represented By The Department Of Health And Human Services Simian-human HAV having a chimeric 2C protein
JP2005528882A (ja) * 2001-10-12 2005-09-29 カイロン コーポレイション A型肝炎ウイルスのヌクレオチド配列、組換えタンパク質およびそれらの使用
CU23202A1 (es) * 2003-01-31 2007-05-18 Ct Ingenieria Genetica Biotech ANTIGENOS RECOMBINANTES DEL VIRUS DE LA HEPATITIS A OBTENIDOS EN CéLULAS VEGETALES
EP2412830B1 (de) 2004-07-13 2014-11-19 Gen-Probe Incorporated Zusammensetzungen und Verfahren zur Detektion von Hepatitis-A-Virus-Nukleinsäure

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL63224A (en) * 1980-07-17 1985-05-31 Scripps Clinic Res Synthetic peptide specific antigenic determinant and method of manufacturing antigenic materials therefrom
DE3112338C2 (de) * 1981-03-28 1995-02-23 Klaus Von Der Helm Verwendung von Hybridisierungssonden zum Nachweis von HAV
US4719177A (en) * 1981-04-20 1988-01-12 Massachusetts Institute Of Technology Production of complementary DNA representing RNA viral sequences by recombinant DNA methods and uses therefor
EP0154587B1 (de) * 1984-03-02 1991-05-15 Merck & Co. Inc. DNS-Fragmente welche für Peptide kodieren, die fähig sind in vivo die Synthese von Antihepatitis-A-Virus-Antikörpern zu induzieren

Also Published As

Publication number Publication date
JPS61500053A (ja) 1986-01-16
EP0162054A1 (de) 1985-11-27
WO1985001517A1 (en) 1985-04-11
EP0162054B1 (de) 1991-03-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee