DE3476806D1 - MURAMYLDIPEPTIDE ACTIVE ESTER DERIVATIVES - Google Patents

MURAMYLDIPEPTIDE ACTIVE ESTER DERIVATIVES

Info

Publication number
DE3476806D1
DE3476806D1 DE8484109847T DE3476806T DE3476806D1 DE 3476806 D1 DE3476806 D1 DE 3476806D1 DE 8484109847 T DE8484109847 T DE 8484109847T DE 3476806 T DE3476806 T DE 3476806T DE 3476806 D1 DE3476806 D1 DE 3476806D1
Authority
DE
Germany
Prior art keywords
muramyldipeptide
active ester
ester derivatives
derivatives
active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484109847T
Other languages
German (de)
Inventor
Toshiyuki Off Res No Hamaoka
Hiromi Fujiwara
Tsuneo C O Daiichi Seiy Kusama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Pharmaceutical Co Ltd
Original Assignee
Daiichi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pharmaceutical Co Ltd filed Critical Daiichi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3476806D1 publication Critical patent/DE3476806D1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE8484109847T 1983-08-18 1984-08-17 MURAMYLDIPEPTIDE ACTIVE ESTER DERIVATIVES Expired DE3476806D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58149617A JPS6042398A (en) 1983-08-18 1983-08-18 Muramyldipeptide active ester derivative

Publications (1)

Publication Number Publication Date
DE3476806D1 true DE3476806D1 (en) 1989-03-30

Family

ID=15479123

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484109847T Expired DE3476806D1 (en) 1983-08-18 1984-08-17 MURAMYLDIPEPTIDE ACTIVE ESTER DERIVATIVES

Country Status (6)

Country Link
US (1) US4681856A (en)
EP (1) EP0135788B1 (en)
JP (1) JPS6042398A (en)
KR (1) KR910008107B1 (en)
CA (1) CA1269500A (en)
DE (1) DE3476806D1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2564096B1 (en) * 1984-05-11 1988-02-19 Anvar LIPOPHILIC DERIVATIVES OF MURAMYLPEPTIDES HAVING MACROPHAGE ACTIVATION PROPERTIES, COMPOSITIONS CONTAINING THEM AND PROCESS FOR OBTAINING THE SAME
JPS6157597A (en) * 1984-08-29 1986-03-24 Toshiyuki Hamaoka Active ester derivative of muramyl peptide
JPS61275299A (en) * 1985-05-29 1986-12-05 Akira Hasegawa Deoxymuramyldipeptide derivative
US4895835A (en) * 1987-11-20 1990-01-23 Nisshin Oil Mills, Ltd. Muramyl peptide derivatives and use thereof
NZ240369A (en) * 1990-10-30 1993-09-27 Daiichi Seiyaku Co Muramyl dipeptide derivatives and vaccine compositions
AU7352498A (en) * 1997-04-11 1998-11-11 Kaluzhin, Oleg Vitalievich Immunomodulator and pharmaceutical compositions with antitumor properties, and afood additive
KR100564325B1 (en) * 2001-12-21 2006-03-29 주식회사 포스코 Hot rolled low alloy steel with good carbon dioxide corrosion resistance and hydrogen induced cracking resistance

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH613709A5 (en) * 1975-12-10 1979-10-15 Ciba Geigy Ag Process for the preparation of glucosamine derivatives
GB1571133A (en) * 1976-04-26 1980-07-09 Syntex Inc Immuniological adjuvant peptidoglycans compounds and methods of preparation thereof
FR2442241A2 (en) * 1978-03-20 1980-06-20 Anvar NOVEL ESTER COMPOUNDS OF MURAMYL-PEPTIDE, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, IN PARTICULAR IN THE FORM OF LIPOSOMES
FR2420545A1 (en) * 1978-03-20 1979-10-19 Anvar NEW ESTERS OF N-ACETYL-MURAMYL-AMINOACYL-GLUTAMIC ACID OR SUBSTITUTION DERIVATIVES THEREOF WITH ANTI-INFECTIOUS PROPERTIES AND / OR IMMUNOLOGICAL ADJUVANTS
JPS55111499A (en) * 1979-02-21 1980-08-28 Takeda Chem Ind Ltd Glucosamine derivative and its preparation

Also Published As

Publication number Publication date
JPH0421680B2 (en) 1992-04-13
KR910008107B1 (en) 1991-10-10
JPS6042398A (en) 1985-03-06
EP0135788B1 (en) 1989-02-22
CA1269500A (en) 1990-05-22
EP0135788A1 (en) 1985-04-03
US4681856A (en) 1987-07-21
KR850001766A (en) 1985-04-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee