DE3476806D1 - MURAMYLDIPEPTIDE ACTIVE ESTER DERIVATIVES - Google Patents
MURAMYLDIPEPTIDE ACTIVE ESTER DERIVATIVESInfo
- Publication number
- DE3476806D1 DE3476806D1 DE8484109847T DE3476806T DE3476806D1 DE 3476806 D1 DE3476806 D1 DE 3476806D1 DE 8484109847 T DE8484109847 T DE 8484109847T DE 3476806 T DE3476806 T DE 3476806T DE 3476806 D1 DE3476806 D1 DE 3476806D1
- Authority
- DE
- Germany
- Prior art keywords
- muramyldipeptide
- active ester
- ester derivatives
- derivatives
- active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108010042708 Acetylmuramyl-Alanyl-Isoglutamine Proteins 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- BSOQXXWZTUDTEL-ZUYCGGNHSA-N muramyl dipeptide Chemical compound OC(=O)CC[C@H](C(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](C)O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](O)[C@@H]1NC(C)=O BSOQXXWZTUDTEL-ZUYCGGNHSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
- C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP58149617A JPS6042398A (en) | 1983-08-18 | 1983-08-18 | Muramyldipeptide active ester derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3476806D1 true DE3476806D1 (en) | 1989-03-30 |
Family
ID=15479123
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8484109847T Expired DE3476806D1 (en) | 1983-08-18 | 1984-08-17 | MURAMYLDIPEPTIDE ACTIVE ESTER DERIVATIVES |
Country Status (6)
Country | Link |
---|---|
US (1) | US4681856A (en) |
EP (1) | EP0135788B1 (en) |
JP (1) | JPS6042398A (en) |
KR (1) | KR910008107B1 (en) |
CA (1) | CA1269500A (en) |
DE (1) | DE3476806D1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2564096B1 (en) * | 1984-05-11 | 1988-02-19 | Anvar | LIPOPHILIC DERIVATIVES OF MURAMYLPEPTIDES HAVING MACROPHAGE ACTIVATION PROPERTIES, COMPOSITIONS CONTAINING THEM AND PROCESS FOR OBTAINING THE SAME |
JPS6157597A (en) * | 1984-08-29 | 1986-03-24 | Toshiyuki Hamaoka | Active ester derivative of muramyl peptide |
JPS61275299A (en) * | 1985-05-29 | 1986-12-05 | Akira Hasegawa | Deoxymuramyldipeptide derivative |
US4895835A (en) * | 1987-11-20 | 1990-01-23 | Nisshin Oil Mills, Ltd. | Muramyl peptide derivatives and use thereof |
NZ240369A (en) * | 1990-10-30 | 1993-09-27 | Daiichi Seiyaku Co | Muramyl dipeptide derivatives and vaccine compositions |
AU7352498A (en) * | 1997-04-11 | 1998-11-11 | Kaluzhin, Oleg Vitalievich | Immunomodulator and pharmaceutical compositions with antitumor properties, and afood additive |
KR100564325B1 (en) * | 2001-12-21 | 2006-03-29 | 주식회사 포스코 | Hot rolled low alloy steel with good carbon dioxide corrosion resistance and hydrogen induced cracking resistance |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH613709A5 (en) * | 1975-12-10 | 1979-10-15 | Ciba Geigy Ag | Process for the preparation of glucosamine derivatives |
GB1571133A (en) * | 1976-04-26 | 1980-07-09 | Syntex Inc | Immuniological adjuvant peptidoglycans compounds and methods of preparation thereof |
FR2442241A2 (en) * | 1978-03-20 | 1980-06-20 | Anvar | NOVEL ESTER COMPOUNDS OF MURAMYL-PEPTIDE, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, IN PARTICULAR IN THE FORM OF LIPOSOMES |
FR2420545A1 (en) * | 1978-03-20 | 1979-10-19 | Anvar | NEW ESTERS OF N-ACETYL-MURAMYL-AMINOACYL-GLUTAMIC ACID OR SUBSTITUTION DERIVATIVES THEREOF WITH ANTI-INFECTIOUS PROPERTIES AND / OR IMMUNOLOGICAL ADJUVANTS |
JPS55111499A (en) * | 1979-02-21 | 1980-08-28 | Takeda Chem Ind Ltd | Glucosamine derivative and its preparation |
-
1983
- 1983-08-18 JP JP58149617A patent/JPS6042398A/en active Granted
-
1984
- 1984-08-17 CA CA000461292A patent/CA1269500A/en not_active Expired - Lifetime
- 1984-08-17 DE DE8484109847T patent/DE3476806D1/en not_active Expired
- 1984-08-17 EP EP84109847A patent/EP0135788B1/en not_active Expired
- 1984-08-18 KR KR1019840004979A patent/KR910008107B1/en not_active IP Right Cessation
- 1984-08-20 US US06/641,905 patent/US4681856A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH0421680B2 (en) | 1992-04-13 |
KR910008107B1 (en) | 1991-10-10 |
JPS6042398A (en) | 1985-03-06 |
EP0135788B1 (en) | 1989-02-22 |
CA1269500A (en) | 1990-05-22 |
EP0135788A1 (en) | 1985-04-03 |
US4681856A (en) | 1987-07-21 |
KR850001766A (en) | 1985-04-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |