DE3466533D1 - Improvements in or relating to the preparation of azetidinone sulfinic acids from cephalosporin sulfones - Google Patents

Improvements in or relating to the preparation of azetidinone sulfinic acids from cephalosporin sulfones

Info

Publication number
DE3466533D1
DE3466533D1 DE8484304957T DE3466533T DE3466533D1 DE 3466533 D1 DE3466533 D1 DE 3466533D1 DE 8484304957 T DE8484304957 T DE 8484304957T DE 3466533 T DE3466533 T DE 3466533T DE 3466533 D1 DE3466533 D1 DE 3466533D1
Authority
DE
Germany
Prior art keywords
relating
preparation
sulfinic acids
cephalosporin sulfones
azetidinone sulfinic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484304957T
Other languages
German (de)
English (en)
Inventor
Lawrence Joseph Mcshane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE3466533D1 publication Critical patent/DE3466533D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
DE8484304957T 1983-07-22 1984-07-20 Improvements in or relating to the preparation of azetidinone sulfinic acids from cephalosporin sulfones Expired DE3466533D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/516,218 US4515719A (en) 1983-07-22 1983-07-22 Azetidinone sulfinic acids from cephalosporin sulfones

Publications (1)

Publication Number Publication Date
DE3466533D1 true DE3466533D1 (en) 1987-11-05

Family

ID=24054617

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484304957T Expired DE3466533D1 (en) 1983-07-22 1984-07-20 Improvements in or relating to the preparation of azetidinone sulfinic acids from cephalosporin sulfones

Country Status (9)

Country Link
US (1) US4515719A (OSRAM)
EP (1) EP0132395B1 (OSRAM)
JP (1) JPS6042365A (OSRAM)
CA (1) CA1249285A (OSRAM)
DE (1) DE3466533D1 (OSRAM)
DK (1) DK355684A (OSRAM)
GB (1) GB2143531B (OSRAM)
HU (1) HU196366B (OSRAM)
IE (1) IE57626B1 (OSRAM)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2043988C1 (ru) * 1991-02-12 1995-09-20 Плива Хандельс ГмбХ 4-оксоазетидин-2-сульфоновые кислоты или их соли в качестве промежуточных продуктов в синтезе бета-лактамовых антибиотиков и способ их получения
US5578721A (en) * 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
SK13897A3 (en) 1996-02-06 1998-05-06 Pliva Pharm & Chem Works 3-bromo- and 3,3-dibromo-4-oxo-1-azetidines, method for preparation thereof and their use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4159266A (en) * 1974-12-24 1979-06-26 Eli Lilly And Company Method of preparation of 3-methylenecephams
US4368156A (en) * 1981-03-09 1983-01-11 Eli Lilly And Company Preparation of 4-haloazetidin-2-ones from 4-sulfinoazetidin-2-ones
ZA828902B (en) * 1981-12-04 1983-09-28 Ciba Geigy Ag Aminobutyl compounds
US4436596A (en) * 1982-11-16 1984-03-13 Eli Lilly And Company N-Substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamido)-4-oxo-azetidines and process

Also Published As

Publication number Publication date
DK355684A (da) 1985-01-23
HU196366B (en) 1988-11-28
EP0132395A1 (en) 1985-01-30
IE57626B1 (en) 1993-02-10
GB2143531A (en) 1985-02-13
US4515719A (en) 1985-05-07
HUT34440A (en) 1985-03-28
EP0132395B1 (en) 1987-09-30
JPS6042365A (ja) 1985-03-06
IE841886L (en) 1985-01-22
GB8418525D0 (en) 1984-08-22
JPH0553788B2 (OSRAM) 1993-08-10
GB2143531B (en) 1987-01-28
DK355684D0 (da) 1984-07-20
CA1249285A (en) 1989-01-24

Similar Documents

Publication Publication Date Title
ZA842874B (en) Substituted cephalosporin sulfones as anti-inflammatory and antidegenerative agents
GB2148330B (en) Improvements in or relating to the granulation of slag
AU582121B2 (en) Improvements in or relating to cephalosporins
GB2181136B (en) Improvements on or relating to 3-bicyclicpyridinium-methyl cephalosporins
ZA843224B (en) Substituted cephalosporins as anti-inflammatory and antidegenerative agents
AU574405B2 (en) The use of ultrapure hyaluronic acid to improve animal joint function
AU566080B2 (en) Improvements in or relating to cephalosporin derivatives
AU6033686A (en) Improvements in or relating to the production of engineering components
DE3474551D1 (en) Improvements in or relating to the preparation of 3-exomethylene cephalosporins
DE3466533D1 (en) Improvements in or relating to the preparation of azetidinone sulfinic acids from cephalosporin sulfones
GB8417178D0 (en) Preparation of 3 3 3-trifluoro-2-trifluoromethylpropene
GB2137997B (en) Improvements in or relating to indolylglycyl cephalosporin derivatives
GB2144126B (en) Penem carboxylix acids and the preparation thereof
GB2133842B (en) Improvements in or relating to the sealing of casings
ZW4384A1 (en) Improvements in or relating to benzothienylglycyl cephalosporin derivatives
GB8416629D0 (en) Preparation of 3 11-dimethyl-2-nonacosanone
IL72481A (en) Preparation of azetidinone sulfinic acids from cephalosporin sulfones
IL71496A0 (en) Improvements in or relating to benzothienylglycyl cephalosporin derivatives
GB8314001D0 (en) Preparation of alphahaloalkyl esters
IL71495A0 (en) Improvements in or relating to the preparation of 3-benzothienylglycines
ZM1684A1 (en) Improvements in or relating to naphthylglycyl cephalosporin derivatives
GB8403962D0 (en) Preparation of aryloxybenzoic acids
GB2143266B (en) Improvements relating to the closing of mineshafts
GB2207086B (en) Improvements in or relating to the fixing of components
SU1149068A1 (en) Joint of components

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee