DE3410641A1 - Vitamin-containing skin protective composition - Google Patents

Vitamin-containing skin protective composition

Info

Publication number
DE3410641A1
DE3410641A1 DE19843410641 DE3410641A DE3410641A1 DE 3410641 A1 DE3410641 A1 DE 3410641A1 DE 19843410641 DE19843410641 DE 19843410641 DE 3410641 A DE3410641 A DE 3410641A DE 3410641 A1 DE3410641 A1 DE 3410641A1
Authority
DE
Germany
Prior art keywords
skin
vitamin
agent according
allergies
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19843410641
Other languages
German (de)
Inventor
Roshdy Dipl.-Chem. Dr. 5000 Köln Ismail
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DE19843410641 priority Critical patent/DE3410641A1/en
Priority to EP89112798A priority patent/EP0343694B1/en
Priority to DE8585102222T priority patent/DE3579343D1/en
Priority to CA000475486A priority patent/CA1257200A/en
Priority to EP85102222A priority patent/EP0158090B1/en
Priority to AT89112798T priority patent/ATE82684T1/en
Priority to AT85102222T priority patent/ATE55905T1/en
Priority to DE8989112798T priority patent/DE3586859D1/en
Publication of DE3410641A1 publication Critical patent/DE3410641A1/en
Priority to US07/211,125 priority patent/US4938960A/en
Priority to US07/877,377 priority patent/US5541220A/en
Priority to US08/298,612 priority patent/US5652261A/en
Priority to US08/819,097 priority patent/US5786384A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations

Abstract

Skin protective composition by the combination of B carotene and canthaxanthin and derivatives thereof with vitamin E.

Description

Es ist bekannt, daß nach der Einnahme von oralem Vitamin E eineIt is known that after taking oral vitamin E, a

Anreicherung in der Haut stattfindet.Accumulation takes place in the skin.

Shiratori Life. Sci. 14, 929 (1974) Diese Anreicherung in der Haut bringt zahlreiche Vorteile, die überraschend und bisher nicht bekannt waren: 1) Schutz der Haut vor Allergien, insbesondere Sonnenallergien und Schutz vor UV-Strahlen 2) Bei Pigmentstörungen der Haut bzw. der Neigung dazu, wird diese verzögert bzw. stagniert und die Behandlung wird beschleunigt. 3) Patienten, die empfindlichHaut haben bzw. deren Haut zu Exembildung, Hautentzündung, Juckreiz, Hautflechte, Akne Vulgaris etc neigt, können mit Vitamin E bzw. des o.g.Shiratori Life. Sci. 14, 929 (1974) This enrichment in the skin brings numerous advantages that were surprising and not previously known: 1) Protection of the skin against allergies, in particular sun allergies and protection against UV rays 2) In the case of pigment disorders of the skin or the tendency to do so, this is delayed or stagnated and the treatment is accelerated. 3) Patients who have sensitive skin or whose skin is prone to exeme formation, skin inflammation, itching, skin lichen, acne vulgaris etc. can take vitamin E or the above

Kombination behandelt werden. Combination are treated.

Die Stagnierung der Hautfalten oder Hautstreifen bzw. deren Vorbeugung kann durch Vitamin E und den erfindungsgemäßen Kombinationen erreicht werden.The stagnation of skin folds or strips of skin or their prevention can be achieved by vitamin E and the combinations according to the invention.

Auch bei Patienten, deren Haut zu Wucherung neigt bzw. zur Krebs bildung kann Vitamin E insbesondere seine Kombinationen mit B-Carotin und Canthaxanthin oder deren Derivate verwendet werden.Also in patients whose skin tends to overgrow or to develop cancer Vitamin E in particular can be its combinations with B-carotene and canthaxanthin or their derivatives are used.

Vitamin E in oraler Form muß hoch genug dosiert sein und zwar zwischen 200 bis 500 mg pro Darreichungsform bzw. Kapsel, vorzugsweise zwischen 300 und 500 mg pro Einheit bzw. Kapsel.Vitamin E in oral form must be dosed in high enough doses between 200 to 500 mg per dosage form or capsule, preferably between 300 and 500 mg per unit or capsule.

B-Carotin kann bis maximal 30 mg pro Einheit verwendet werden, während Canthaxanthin zwischen 10 und 50 mg, vorzugsweise zwischen 20 und 40 mg verwendet werden kann.B-carotene can be used up to a maximum of 30 mg per unit while Canthaxanthin used between 10 and 50 mg, preferably between 20 and 40 mg can be.

Man kann auch einen oder mehrere Vitamine der B-Reihe oder Dexapanthenol bzw. CAlcium Pantothenat zusetzen.One can also use one or more B-series vitamins or dexapanthenol or add calcium pantothenate.

Beispiel 1 Kapseln aus: 35 mg Oanthaxanthin 8 mg B-Carotin 8. mg Calcium D Pantothenat 0,15 mg D-Biotin 250 mg Lecithin 400 mg Dl-alpha-Tocopherolacetat 80 mg Sojabohnenöl Beispiel 2 Kapseln aus: 30 mg Canthaxanthin 300 mg DTalpha-Tocopherol-Konzentrat 150 mg Sojabohnenöl Beispiel 3 Kapseln aus: 15 mg B-Carotin 400 mg D-alpha-Tocopherolacetat 120 mg SojabohnenölExample 1 Capsules made from: 35 mg Oanthaxanthin 8 mg B-Carotene 8. mg Calcium D pantothenate 0.15 mg D-biotin 250 mg lecithin 400 mg Dl-alpha-tocopherol acetate 80 mg soybean oil Example 2 capsules made from: 30 mg canthaxanthin 300 mg DTalpha-tocopherol concentrate 150 mg soybean oil Example 3 capsules made from: 15 mg B-carotene 400 mg D-alpha-tocopherol acetate 120 mg soybean oil

Claims (3)

Vitaminhaltige Hautschutzmittel Patentansprüche 1) Hautschutzmittel, dadurch gekennzeichnet, daß man Vitamin E in Kombination mit Hautpigmentveränderungsmitteln bzw. Bräunungsmitteln, wie z. B. B-Carotin und/oder Canthaxanthin bzw. deren Derivate in oraler Form, vorzugsweise Kapseln, verwendet.Vitamin-containing skin protection agents Patent claims 1) Skin protection agents, characterized in that vitamin E is used in combination with skin pigment change agents or tanning agents, such as. B. B-carotene and / or canthaxanthin or their derivatives used in oral form, preferably capsules. 2) Hautschutzmittel nach Anspruch 1, dadurch gekennzeichnet, daß man obiges Mittel bei Hautallergien bzw. deren Vorbeugung, insbesondere Sonnenällergien und/oder UV-Allergien verwendet.2) skin protection agent according to claim 1, characterized in that one The above remedy for skin allergies or their prevention, especially sun allergies and / or UV allergies used. 3) Hautschutzmittel nach Anspruch 1, dadurch gekennzeichnet, daß man obiges Mittel bei Hautpigmentstörungen bzw. zur Vorbeugung von Hautpigmentstörungen verwendet.3) skin protection agent according to claim 1, characterized in that one The above remedy for skin pigment disorders or for the prevention of skin pigment disorders used. t) Hautschutzmittel nach Anspruch 1, dadurch gekennzeichnet, daß sie bei empfindlicher Haut bzw. zur Vorbeugung der verschiedenen Hautkrankheiten, wie Exemen, Hautflechte, Hautentzündungen, Juckreiz, verwendet.t) skin protection agent according to claim 1, characterized in that it for sensitive skin or to prevent various skin diseases such as Exemen, skin lichen, skin inflammation, itching, used. 5? Hautschutzmittel, nach Anspruch 1, dadurch gekennzeIchnet, daß man sie gegen Hautf btbM bzw. Hautstreifen einstzt bzw.5? Skin protection agent according to claim 1, characterized in that you use them against skin f btbM or skin strips or verwendet. used.
DE19843410641 1984-03-07 1984-03-23 Vitamin-containing skin protective composition Withdrawn DE3410641A1 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
DE19843410641 DE3410641A1 (en) 1984-03-23 1984-03-23 Vitamin-containing skin protective composition
AT89112798T ATE82684T1 (en) 1984-03-07 1985-02-28 MEANS FOR TREATMENT AND PROTECTION OF THE SKIN.
DE8585102222T DE3579343D1 (en) 1984-03-07 1985-02-28 AGENTS FOR TREATING AND PROTECTING THE SKIN.
CA000475486A CA1257200A (en) 1984-03-07 1985-02-28 Agents for the treatment and protection of the skin
EP85102222A EP0158090B1 (en) 1984-03-07 1985-02-28 Drug for the treatment and the protection of the skin
EP89112798A EP0343694B1 (en) 1984-03-07 1985-02-28 Agent for the treatmment and protection of the skin
AT85102222T ATE55905T1 (en) 1984-03-07 1985-02-28 MEANS FOR TREATMENT AND PROTECTION OF THE SKIN.
DE8989112798T DE3586859D1 (en) 1984-03-07 1985-02-28 AGENTS FOR TREATING AND PROTECTING THE SKIN.
US07/211,125 US4938960A (en) 1984-03-07 1988-06-21 Agents for the treatment and protection of the skin
US07/877,377 US5541220A (en) 1984-03-07 1992-04-29 Agents for the treatment and protection of the skin
US08/298,612 US5652261A (en) 1984-03-07 1994-08-31 Method for the treatment and protection of the skin
US08/819,097 US5786384A (en) 1984-03-07 1997-03-18 Agents for the treatment and protection of the skin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843410641 DE3410641A1 (en) 1984-03-23 1984-03-23 Vitamin-containing skin protective composition

Publications (1)

Publication Number Publication Date
DE3410641A1 true DE3410641A1 (en) 1985-10-24

Family

ID=6231354

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19843410641 Withdrawn DE3410641A1 (en) 1984-03-07 1984-03-23 Vitamin-containing skin protective composition

Country Status (1)

Country Link
DE (1) DE3410641A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19605659A1 (en) * 1996-02-15 1997-08-21 Rainer Dr Zierer Compositions containing beta-carotene and vitamin=E
WO2005082360A1 (en) * 2004-02-27 2005-09-09 Basf Aktiengesellschaft Peroral preparations containing vitamin e

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19605659A1 (en) * 1996-02-15 1997-08-21 Rainer Dr Zierer Compositions containing beta-carotene and vitamin=E
DE19605659B4 (en) * 1996-02-15 2011-03-10 Safetec Gmbh Use of a combination of beta-carotene and vitamin E derivatives for the treatment of epithelial differentiation disorders
WO2005082360A1 (en) * 2004-02-27 2005-09-09 Basf Aktiengesellschaft Peroral preparations containing vitamin e

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