DE3408260A1 - Suppositories containing vitamin E - Google Patents

Suppositories containing vitamin E

Info

Publication number
DE3408260A1
DE3408260A1 DE19843408260 DE3408260A DE3408260A1 DE 3408260 A1 DE3408260 A1 DE 3408260A1 DE 19843408260 DE19843408260 DE 19843408260 DE 3408260 A DE3408260 A DE 3408260A DE 3408260 A1 DE3408260 A1 DE 3408260A1
Authority
DE
Germany
Prior art keywords
vitamin
suppositories
contain
treatment
containing vitamin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19843408260
Other languages
German (de)
Inventor
Roshdy Dipl.-Chem. Dr. 5000 Köln Ismail
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DE19843408260 priority Critical patent/DE3408260A1/en
Priority to DE8585100749T priority patent/DE3582935D1/en
Priority to AT89120921T priority patent/ATE116850T1/en
Priority to AT85100749T priority patent/ATE63812T1/en
Priority to EP89120921A priority patent/EP0366156B1/en
Priority to DE3587978T priority patent/DE3587978D1/en
Priority to EP85100749A priority patent/EP0151987B1/en
Priority to US06/700,462 priority patent/US4612194A/en
Priority to EP85101554A priority patent/EP0152106B1/en
Priority to CA000474194A priority patent/CA1261750A/en
Priority to AT85101554T priority patent/ATE67665T1/en
Priority to DE8585101554T priority patent/DE3584174D1/en
Publication of DE3408260A1 publication Critical patent/DE3408260A1/en
Priority to US06/898,499 priority patent/US4983626A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E

Abstract

Published without abstract.

Description

In der Hauptanmeldung "Mittel zur Behandlung von ErkrankungenIn the main application "Means for the treatment of diseases

des Analbereichs" (P 340 2930.3), ist die Verwendung von Vitamin E als Suppositorien zur Behandlung, auch die Kombination von Vitamin E mit durchblutungsfördernden und/oder gefäßerweiternden Mitteln beschrieben worden.of the anal area "(P 340 2930.3), is the use of vitamin E. as suppositories for treatment, also the combination of vitamin E with blood circulation-promoting and / or vasodilators have been described.

Es wurde hier auch gefunden, daß diese Suppositorien bei der Behandlung von Rheuma- und Venenerkrankungen Erfolge bringen.It was also found here that these suppositories are useful in treating of rheumatism and venous diseases bring success.

Bei der Behandlung bzw. Anregung der Sexualbereiche und Organe konnten ebenfalls die Vitamin-E-Suppositorien zur Verbesserung und Beseitigung der Symptome eingesetzt werden.In the treatment or stimulation of the sexual areas and organs could also the vitamin E suppositories to improve and eliminate symptoms can be used.

Es mußten jedoch bei den Einsatzgebieten bzw. bei den verschiedenen Anwendungen die geeigneten Zusatzstoffe zur unterstützenden Behandlung ausgewählt werden.However, it had to be in the areas of application or in the various Applications the appropriate additives are selected for supportive treatment will.

Die üblichen Hilfsstoffe sowie Trägerstoffe können bei der Herstellung von Suppositorien eingesetzt werden. Es können auch Weichgelatine Rektal-Kapseln und Emulgatoren verwendet werden.The usual auxiliaries and carriers can be used in the production used by suppositories. It can also use soft gelatin rectal capsules and emulsifiers can be used.

Man kann jedoch auch Suppositorien, die hochdosicrtes Vitamin E allein enthalten, zur Behandlung obiger Krankheiten bzw. zur Anregung der Sexualbereiche verwenden.However, one can also use suppositories that contain high-dose vitamin E alone for the treatment of the above diseases or to stimulate the sexual areas use.

Die Kombination mit durchblutungsfördernden Mitteln wie z.B.The combination with blood circulation-promoting agents such as

Extract Hippocastani oder B-Hydroxyäthylrutoside bzw. auch Rutosidderivate, die mehrere Hydroxyäthyl-Gruppen enthalten, können verwendet werden. Nicotinsäure bzw. deren Ester oder Derivate, wie z. B. Nicotinsäurebenzylester oder Nicotinsäure-B-Hydroxyäthylester etc. können Vorteile bringen und die Wirkung von Vitamin E steigern und den Heilungsprozeß verkürzen.Extract Hippocastani or B-Hydroxyäthylrutoside or also rutoside derivatives, which contain several hydroxyethyl groups can be used. Nicotinic acid or their esters or derivatives, such as. B. benzyl nicotinate or B-hydroxyethyl nicotinate etc. can bring benefits and increase the effects of vitamin E and the healing process shorten.

Zur Behandlung bzw. Anregung der Sexualorgane können weitere nützliche Stoffe, wie Extract muirae puamae, Extract testes bovis, z. B. wässrige Auszüge aus diesen Stoffen oder ähnliche Produkte eingesetzt werden.For the treatment or stimulation of the sexual organs can be further useful Substances such as Extract muirae puamae, Extract testes bovis, e.g. B. aqueous extracts made of these substances or similar products are used.

Auch solche Vitamin-E-Suppositorien können zur Behandlung der verschiedenen bekannten Prostata-Krankheiten wie z.B. Entzündung oder stauung 4 zur Einleitllngsbollcl1ldlllng verwendet werden. Zur Einleitungsbehandlung bei InScrt;i]ität, zur Anregung der Sexualorgane wird eine Menge zwischen 100 - 500 mg Vitamin E pro Suppositorium bevorzugt. Typische Beispiele enthalten 200 - 450 mg Vitamin E.Even such vitamin E suppositories can be used to treat the various well-known prostate diseases such as inflammation or congestion 4 for introductory discharge be used. For introductory treatment in InScrt; i] ität, to stimulate the Sex organs gets an amount between 100 - 500 mg of vitamin E. Per Suppository preferred. Typical examples contain 200-450 mg of vitamin E.

Der Vorteil der Verwendung von Suppositorien liegt darin, daß Vitamin E durch die Magensäure zum Teil zerstört wird, während es hier voll ausgenutzt bzw. voll verwendet wird.The advantage of using suppositories is that it is vitamin E is partly destroyed by the stomach acid, while here it is fully utilized or is fully used.

Erfindungsgemäße Kombinationen mit ausreichenden Mengen an Vitamin E verbessern außerdem die Durchblutung der Extremitäten, der Peripherie des Auges, des Innenohres und des Cerebrum.Combinations according to the invention with sufficient amounts of vitamin E also improve blood flow to the extremities, the periphery of the eye, of the inner ear and cerebrum.

Die Wirksamkeit von Vitamin F. bei dieser Kombination ist besonders überraschend und ermöglicht weitere neue Anwendungsgebiete für dieses Vitamin.The effectiveness of vitamin F. in this combination is special surprising and enables further new areas of application for this vitamin.

In dieser Erfindung wird hauptsächlich das Freie alpha-Tocopherol verwendet.In this invention the free alpha-tocopherol is mainly used used.

Beispiel 1 Suppositorien enthalten: 250 mg D-alpha-Tocopherol-Konzentrat 30 mg Nicotinsäurebenzylester 100 mg getrockneten,enteiweißten, wässrigen Auszug aus testis bovis 70 mg Extract muirae puamae sicc.Example 1 Suppositories contain: 250 mg D-alpha-tocopherol concentrate 30 mg benzyl nicotinate 100 mg dried, deproteinized, aqueous extract from testis bovis 70 mg extract muirae puamae sicc.

ad 2,0 g Stadimol Beispiel 2 Suppositorien enthalten: 450 mg dl-alpha-Tocopherol 40 mg Cetiol (Ölsäureoleylester) 150 mg Zinkoxid ad 2,0 g Stadimol Beispiel 3 Suppositorien enthalten: 400 mg Vitamin E 200 mg B-Hydroxyäthylrutoside 40 mg Cetiol ad 2,0 g Stadimol Beispiel 4 Suppositorien enthalten: 250 mg Vitamin E 250 mg Extract Hippocastani (enthält ca. 80 mg Aescin) ad 2,0 g Stadimol Beispiel 5 gemäß Beispiel 3 wurden Suppositorien hergestellt, jedoch mit 300 mg Vitamin E und 200 mg Tri-äthy:tosidead 2.0 g Stadimol Example 2 suppositories contain: 450 mg dl-alpha-tocopherol 40 mg cetiol (oleic acid oleyl ester) 150 mg zinc oxide ad 2.0 g stadimol Example 3 Suppositories contain: 400 mg vitamin E 200 mg B-hydroxyethyl rutoside 40 mg cetiol ad 2.0 g Stadimol Example 4 suppositories contain: 250 mg of vitamin E 250 mg of Hippocastani extract (contains approx. 80 mg escin) ad 2.0 g Stadimol Example 5 according to Example 3 were Suppositories made, but with 300 mg vitamin E and 200 mg tri-ethy: toside

Claims (3)

Patentansprüche 1) Suppositorien als Rheuma- und Venenmittel bzw. zur Behandlung des Sexualbereichs und -organe, dadurch gekennzeichnet, daß sie Vitamin E und die übrigen Trägerhilfsstoffe bzw. Emulgatoren enthalten. Claims 1) Suppositories as rheumatism and venous remedies or for the treatment of the sexual area and organs, characterized in that they contain vitamins E and the other carrier auxiliaries or emulsifiers contain. 2) Suppositorien anch Anspruch 1), dadurch gekennzeichnet, daß sie Vitamin E zwischen 30 - 600 mg, sowie die üblichen Trägerhilfsstoffe bzw. Emulgatoren enthalten.2) suppositories according to claim 1), characterized in that they Vitamin E between 30 - 600 mg, as well as the usual excipients or emulsifiers contain. 3) Suppositorien nach Anspruch 1), dadurch gekennzeichnet, daß sie 30- 500 mg Vitamin E und zusätzlich ein oder mehrere gefäß erweiternde und/oder durchblutungsfördernde Mittel enthalten.3) suppositories according to claim 1), characterized in that they 30-500 mg of vitamin E plus one or more vasodilators and / or contain blood circulation-enhancing agents.
DE19843408260 1984-01-28 1984-03-07 Suppositories containing vitamin E Withdrawn DE3408260A1 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
DE19843408260 DE3408260A1 (en) 1984-03-07 1984-03-07 Suppositories containing vitamin E
DE8585100749T DE3582935D1 (en) 1984-01-28 1985-01-25 AGENTS FOR TREATING DISEASES OF THE Veins AND ANAL AREA.
AT89120921T ATE116850T1 (en) 1984-01-28 1985-01-25 AGENTS FOR THE TREATMENT OF DISEASES OF THE VEINS AND ANAL AREA.
AT85100749T ATE63812T1 (en) 1984-01-28 1985-01-25 MEANS FOR TREATMENT OF DISEASES OF VEINS AND ANAL AREA.
EP89120921A EP0366156B1 (en) 1984-01-28 1985-01-25 Composition for the treatment of diseases of the veins and the anal region
DE3587978T DE3587978D1 (en) 1984-01-28 1985-01-25 Agents for the treatment of diseases of the veins and the anal area.
EP85100749A EP0151987B1 (en) 1984-01-28 1985-01-25 Means for the treatment of diseases of the veins and the anal region
US06/700,462 US4612194A (en) 1984-02-15 1985-02-11 Anti-rheumatic agents and their use
EP85101554A EP0152106B1 (en) 1984-02-15 1985-02-13 Antirheumatic compositions
CA000474194A CA1261750A (en) 1984-02-15 1985-02-13 Anti-rheumatic agents and their use
AT85101554T ATE67665T1 (en) 1984-02-15 1985-02-13 ANTI-RHEUMED.
DE8585101554T DE3584174D1 (en) 1984-02-15 1985-02-13 RHEUMA means.
US06/898,499 US4983626A (en) 1984-02-15 1986-08-21 Anti-rheumatic agents and their use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843408260 DE3408260A1 (en) 1984-03-07 1984-03-07 Suppositories containing vitamin E

Publications (1)

Publication Number Publication Date
DE3408260A1 true DE3408260A1 (en) 1985-09-26

Family

ID=6229752

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19843408260 Withdrawn DE3408260A1 (en) 1984-01-28 1984-03-07 Suppositories containing vitamin E

Country Status (1)

Country Link
DE (1) DE3408260A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001017479A2 (en) * 1999-09-09 2001-03-15 Androsolutions, Inc. Methods and compositions for preventing and treating prostate disorders
US6642274B1 (en) 1999-09-09 2003-11-04 Gary W. Neal Methods and compositions for preventing and treating prostate disorders

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001017479A2 (en) * 1999-09-09 2001-03-15 Androsolutions, Inc. Methods and compositions for preventing and treating prostate disorders
WO2001017479A3 (en) * 1999-09-09 2001-09-20 Androsolutions Inc Methods and compositions for preventing and treating prostate disorders
US6642274B1 (en) 1999-09-09 2003-11-04 Gary W. Neal Methods and compositions for preventing and treating prostate disorders

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