DE3379206D1 - Mutation assays involving blood cells that metabolize toxic substances - Google Patents

Mutation assays involving blood cells that metabolize toxic substances

Info

Publication number
DE3379206D1
DE3379206D1 DE8383902509T DE3379206T DE3379206D1 DE 3379206 D1 DE3379206 D1 DE 3379206D1 DE 8383902509 T DE8383902509 T DE 8383902509T DE 3379206 T DE3379206 T DE 3379206T DE 3379206 D1 DE3379206 D1 DE 3379206D1
Authority
DE
Germany
Prior art keywords
blood cells
toxic substances
assays involving
involving blood
mutation assays
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383902509T
Other languages
English (en)
Inventor
Charles Crespi
William Thilly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Application granted granted Critical
Publication of DE3379206D1 publication Critical patent/DE3379206D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00—Treatment of water, waste water, or sewage
    • C02F1/02—Treatment of water, waste water, or sewage by heating
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24D—DOMESTIC- OR SPACE-HEATING SYSTEMS, e.g. CENTRAL HEATING SYSTEMS; DOMESTIC HOT-WATER SUPPLY SYSTEMS; ELEMENTS OR COMPONENTS THEREFOR
    • F24D11/00—Central heating systems using heat accumulated in storage masses
    • F24D11/02—Central heating systems using heat accumulated in storage masses using heat pumps
    • F24D11/0214—Central heating systems using heat accumulated in storage masses using heat pumps water heating system
    • F24D11/0235—Central heating systems using heat accumulated in storage masses using heat pumps water heating system with recuperation of waste energy
    • F24D11/025—Central heating systems using heat accumulated in storage masses using heat pumps water heating system with recuperation of waste energy contained in waste water
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24V—COLLECTION, PRODUCTION OR USE OF HEAT NOT OTHERWISE PROVIDED FOR
    • F24V99/00—Subject matter not provided for in other main groups of this subclass
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
    • F25B30/00—Heat pumps
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • G01N33/5017—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity for testing neoplastic activity
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02B—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO BUILDINGS, e.g. HOUSING, HOUSE APPLIANCES OR RELATED END-USER APPLICATIONS
    • Y02B30/00—Energy efficient heating, ventilation or air conditioning [HVAC]
    • Y02B30/52—Heat recovery pumps, i.e. heat pump based systems or units able to transfer the thermal energy from one area of the premises or part of the facilities to a different one, improving the overall efficiency
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Thermal Sciences (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Combustion & Propulsion (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Hydrology & Water Resources (AREA)
  • Environmental & Geological Engineering (AREA)
  • Water Supply & Treatment (AREA)
  • Organic Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE8383902509T 1982-07-19 1983-07-15 Mutation assays involving blood cells that metabolize toxic substances Expired DE3379206D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/399,851 US4532204A (en) 1982-07-19 1982-07-19 Mutation assays involving blood cells that metabolize toxic substances
PCT/US1983/001077 WO1984000379A1 (en) 1982-07-19 1983-07-15 Mutation assays involving blood cells that metabolize toxic substances

Publications (1)

Publication Number Publication Date
DE3379206D1 true DE3379206D1 (en) 1989-03-23

Family

ID=23581227

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383902509T Expired DE3379206D1 (en) 1982-07-19 1983-07-15 Mutation assays involving blood cells that metabolize toxic substances

Country Status (8)

Country Link
US (1) US4532204A (de)
EP (1) EP0113769B1 (de)
JP (1) JPH074236B2 (de)
CA (1) CA1212643A (de)
DE (1) DE3379206D1 (de)
IL (1) IL69268A (de)
IT (1) IT1163816B (de)
WO (1) WO1984000379A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5935829A (en) * 1982-07-19 1999-08-10 Massachusetts Institute Of Technology Mutation assays involving blood cells that metabolize toxic substances
US5169755A (en) * 1986-12-30 1992-12-08 E. I. Du Pont De Nemours And Company Process for inducing cytochrome P-450 enzymes in streptomyces bacteria and determining the mutagenicity of chemicals
US4980281A (en) * 1988-02-10 1990-12-25 Housey Gerard M Method of screening for protein inhibitors and activators
US5688655A (en) * 1988-02-10 1997-11-18 Ict Pharmaceuticals, Inc. Method of screening for protein inhibitors and activators
US5266464A (en) * 1988-02-10 1993-11-30 Ict Pharmaceuticals, Inc. Method of screening for protein inhibitors and activators
FR2658300B1 (fr) * 1990-02-13 1992-05-29 Abx Sa Reactif et methode d'utilisation de celui-ci pour la numeration automatique des leucocytes basophiles du sang en appareils de mesure par variation de resistivite.
DE10056802B4 (de) * 2000-11-14 2005-06-16 Epigenomics Ag Verfahren zur Detektion von Methylierungszuständen zur toxikologischen Diagnostik
WO2004034013A2 (en) * 2002-05-06 2004-04-22 Colorado State University Research Foundation Genotoxicity analysis
CA2567813C (en) 2004-05-23 2015-11-24 Gerard M. Housey Theramutein modulators
US8431110B2 (en) 2005-05-23 2013-04-30 Hmi Medical Innovations, Llc. Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators
JP2009523408A (ja) * 2005-11-23 2009-06-25 ジェラルド・エム・ハウシー タンパク質モジュレーターを同定、合成、最適化および解析する化合物群および方法群

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4036693A (en) * 1976-02-02 1977-07-19 Massachusetts Institute Of Technology Treatment of cell culture microcarries
US4066510A (en) * 1976-05-24 1978-01-03 Massachusetts Institute Of Technology Assay for mutagenesis in diploid human lymphoblasts
US4299915A (en) * 1977-10-17 1981-11-10 Massachusetts Institute Of Technology Assay for mutagenesis in bacterial cells
US4352880A (en) * 1979-09-17 1982-10-05 Massachusetts Institute Of Technology Diffusion bioassay for the quantitative determination of mutagenicity
US4302535A (en) * 1979-09-27 1981-11-24 Massachusetts Institute Of Technology Assay for mutagenesis in heterozygous diploid human lymphoblasts
US4393133A (en) * 1980-06-12 1983-07-12 The Wistar Institute Of Anatomy And Biology Human hepatoma derived cell line, process for preparation thereof, and uses therefor

Also Published As

Publication number Publication date
CA1212643A (en) 1986-10-14
IT8322139A0 (it) 1983-07-19
US4532204A (en) 1985-07-30
EP0113769A1 (de) 1984-07-25
IL69268A0 (en) 1983-11-30
JPS59501442A (ja) 1984-08-16
WO1984000379A1 (en) 1984-02-02
IT1163816B (it) 1987-04-08
JPH074236B2 (ja) 1995-01-25
IL69268A (en) 1987-11-30
EP0113769B1 (de) 1989-02-15

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