DE3370335D1 - Peptide derivatives, process for their preparation and their pharmaceutical use - Google Patents

Peptide derivatives, process for their preparation and their pharmaceutical use

Info

Publication number
DE3370335D1
DE3370335D1 DE8383402404T DE3370335T DE3370335D1 DE 3370335 D1 DE3370335 D1 DE 3370335D1 DE 8383402404 T DE8383402404 T DE 8383402404T DE 3370335 T DE3370335 T DE 3370335T DE 3370335 D1 DE3370335 D1 DE 3370335D1
Authority
DE
Germany
Prior art keywords
preparation
pharmaceutical use
peptide derivatives
peptide
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383402404T
Other languages
English (en)
Inventor
Marie-Helene Charon
Pierre Fromageot
Van Chuong Paul Pham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA filed Critical Commissariat a lEnergie Atomique CEA
Application granted granted Critical
Publication of DE3370335D1 publication Critical patent/DE3370335D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/595—Gastrins; Cholecystokinins [CCK]
    • C07K14/5955—Gastrins; Cholecystokinins [CCK] at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE8383402404T 1982-12-16 1983-12-13 Peptide derivatives, process for their preparation and their pharmaceutical use Expired DE3370335D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8221127A FR2537971A1 (fr) 1982-12-16 1982-12-16 Nouveaux derives peptidiques, leur procede de fabrication et leur utilisation pharmaceutique

Publications (1)

Publication Number Publication Date
DE3370335D1 true DE3370335D1 (en) 1987-04-23

Family

ID=9280185

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383402404T Expired DE3370335D1 (en) 1982-12-16 1983-12-13 Peptide derivatives, process for their preparation and their pharmaceutical use

Country Status (5)

Country Link
US (1) US4530837A (de)
EP (1) EP0115227B1 (de)
JP (1) JPS59130259A (de)
DE (1) DE3370335D1 (de)
FR (1) FR2537971A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2575164B1 (fr) * 1984-12-20 1987-03-20 Sanofi Sa Esters de tri- et tetrapeptides inhibiteurs de la secretion gastrique, procede d'obtention et compositions pharmaceutiques les contenant

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1063728A (en) * 1965-04-12 1967-03-30 Ici Ltd Amide derivatives
US4012367A (en) * 1976-02-05 1977-03-15 G. D. Searle & Co. Anti-ulcer polypeptides containing L-aspartic acid and intermediates thereto
FR2364659A1 (fr) * 1976-09-21 1978-04-14 Commissariat Energie Atomique Medicament antagoniste de l'action de la gastrine et des polypeptides apparentes

Also Published As

Publication number Publication date
JPS59130259A (ja) 1984-07-26
JPH0420000B2 (de) 1992-03-31
EP0115227B1 (de) 1987-03-18
FR2537971A1 (fr) 1984-06-22
EP0115227A1 (de) 1984-08-08
US4530837A (en) 1985-07-23
FR2537971B1 (de) 1985-05-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee