DE3325299A1 - BAG WITH INTEGRATED BREATHABLE SEAL FOR ARTIFICIAL BODY OPENINGS - Google Patents

Description

CR. Bard, Inc. Munich, July 15, 1983

Murray Hill, N.J. 07974 (V.St.A.) 14 336

Bag with integrated breathable
Seal for artificial orifices

The invention relates to devices for artificial body orifices, in particular those of patients Devices used with artificial orifices that have an integral or bonded thin barrier gasket formed from a composition having unique and desirable properties, viz Breathability, adhesion, resistance to Leakage, dissolution and destruction by liquids as well as cohesive strength. The invention relates more particularly on the combination of a special sealing material that acts as a composite layer with a hydrophobic Basis, for example a thermoplastic material, can be formed and that for the integral production is adapted to a conventional device for artificial orifices, for example one Colon pouch or a small intestinal pouch.

The present invention has important improvements over existing artificial body orifice devices on, in particular due to a unique combination of properties brought about by the uniform Device for artificial orifices and a skin barrier can be achieved. By using the present In accordance with the invention, a high degree of conformance, strength and both dry and wet adhesion is achieved, and in this way, at the same time and continuously, irregularities in the area surrounding the stoma are avoided and resistance

ability to prevent fluid leakage is provided, which leads to additional comfort for the wearer, since none Flanges or rings are present, as in many previous devices for artificial orifices, which interfere with movements of the body and cause an unpleasant appearance under clothing.

At present, seals are commonly used for artificial orifice devices based on sterkulin gum powder (Karaya powder) and are described, for example, in US Pat. No. 3,302,647. Sterkulin gum points has certain disadvantages, as it is a nutrient substance and the growth of microorganisms not only during use, but can also assist in the event of contamination during storage before use. Sterkul gum compositions have poor cohesion and therefore tend to dissolve and become slippery when wet, which often leads to the fact that a special adhesive must be provided to prevent accidental removal of to prevent the site of the artificial body opening.

In US Pat. No. 4,160,076, hydrophilic foams are described which are composed of a polyoxyalkylene polyol reagent having a defined average reaction functionality greater than 2, one aqueous reagent and one careful balanced combination of a non-ionic surface-active agent and a liquid foam inhibitor Agent exist. The foams produced are distinguished by the fact that they contain a plurality of larger cells and membranes, which in turn are made up of small cells. In addition, large amount of many can be water-soluble or in water dispersible materials can be added to the aqueous reagent, for example cellulose pigments, dyes, enzymes or the like. By homogeneously distributing these materials in the aqueous reagent, they can ultimately be produced throughout

th foam are distributed. Because of the properties The large cell size and the membranes of the hydrophilic polyurethane sponges do not have the necessary properties Properties, namely adhesiveness, elasticity, sealability and flexibility, as found in a seal are required for artificial orifices.

A gasket for artificial openings that has varying degrees of adhesiveness, lubricity and softness is described in U.S. Patent 3,980,084. The polymer seal described there for artificial body orifices is made by polymerizing a hydroxyalkyl acrylate or methacrylate in the presence of a polyalkylene glycol, a reducing agent or chain limiter, and water. In making the Seals it is imperative that the polymerization reaction is carried out in the presence of water will. This causes a significant amount of water to be absorbed into the polymer matrix during the polymerization reaction. In addition, natural or synthetic rubber or cellulosic materials can be incorporated into the polymer matrix built in to increase the absorption capacity. However, the material described has a very little elongation at break and does not return to its original shape after deformation. In addition, these materials are often highly viscous and therefore do not have the sealability that they are used to Use in an artificial orifice device is preferred, and this can result in a Guide the leak around the seal.

The object of the invention is therefore to overcome the limitations to overcome the known operations and provide a new device for artificial orifices.

The invention has the advantage that a new unitary device for body orifices is provided that has a built-in seal formed from a special sealant composition.

Another advantage of the invention is that it provides a unitary pouch and seal which can be made using conventional techniques and are comfortable and convenient for the wearer are easy to use.

Another advantage of the invention is the provision of a polymer composition suitable for use in contact with the skin and from the non-aqueous reaction of a polyisocyanate and a polyoxyalkylene polyol moiety with a hydrophilic filler that was incorporated into the polyol before the reaction will.

Another advantage of the invention can be seen in the properties of the polymer composition according to the present invention, which is a seal between the device for the body orifice and the skin
(Epidermis) of the human body and has a high degree of adhesiveness, elasticity, flexibility and resistance to body fluids. This prevents movement of the seal around the body opening, which would otherwise lead to leakage of body substances and thereby cause irritation and chafing if they come into repeated or continuous contact with the skin.

Another advantage of the invention is the adaptability with respect to the cohesion of the new. Composition. This property enables it to be molded into preferred shapes, both on the patient's skin and on the skin

Containment containers adhere without the use of additional adhesives. The new composition is soft and pliable and reduces discomfort to the wearer of an artificial orifice device.

Another advantage of the invention can be seen in that the shelf life and resistance to contamination with the new composition Sterkulin gum products that have a limited shelf life and during storage get hard.

A sealing pad or a seal formed from the new composition is between a liquid-resistant one Material v / ie a woven fabric, film, non-woven fabric or the like which is attached to the front of the device is welded for artificial orifices, and the user's skin that the Surrounding the body opening, attached. The sealing cushion is used to hold the released liquids, which in high Measures irritate the skin and can contain microorganisms from the digestive tract and also nauseating Release fragrances. In addition, the sealing cushion helps to hold the device in place and works In addition, it is more comfortable to carry.

The sealing pad of the invention is specifically designed to achieve the functions described in the event. Due to its composition, the pillow can Manufactured in any shape desired, will retain that shape and will not fall apart in use.

The composition used to form the pillow or the Seal is made through the reaction of an organic polyisocyanate with one od = r more di- or polyfunctional Hydroxy! Compounds produced, for example poly-

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oxyalkylene polyols such as those of propylene or ethylene oxide derived, preferably with equivalent weights v; n at least 500. A hydrophilic filler, for example a cellulose or natural rubber, is put into the polyol half of the urethane system prior to the reaction of the polyol with the Polyisocyanate half incorporated.

The soft polymer matrix or adhesive composition formed by the reaction encapsulates the evenly dispersed hydrophilic filler within the self-sustaining adhesive composition. Therefore, the product is resistant to swelling or dissolution by body fluids or their passage, but breathable, which makes it easy to transport and forward gases such as water vapor is made possible.

The ■ new pouch for body orifices according to the invention, which can be made, for example, as a small intestinal bag, ureteral or colon bag, uses the highly elastic, adhesive, rubber-like material as sealing material, and this is with a soft, liquid-resistant Material deposited and cast sufficiently thin that the Hx7; backing material is welded in place or otherwise attached to the plastic film of the artificial device in an integral manner Body openings, and zv / ar directly through the seal.

The invention is explained in more detail below with reference to exemplary embodiments shown in the drawing, from which further features and advantages result.

Show it:

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-A

Fig. 1 is a view of a typical colon pouch in accordance with the present invention;

Figure 2 is an enlarged cross-section through the pouch of Figure 1 taken along lines 2-2; and

Fig. 3 is a view of a typical small intestinal pouch under * Use of the present invention.

In the following, the same parts are denoted by the same reference numerals.

The disclosed invention consists of a unitary arrangement of a bag for artificial body openings, indicated generally at 10, which can be formed in one of several well-known configurations can. The pouch shown in Figure 1 represents a typical colon pouch of the type that they normally use to be used after operations. A surgical procedure such as making a colon, small intestine or ureter opening consists in the formation of an opening (stoma) in the wall of the intestine or the Large intestine, which opening extends through the wall of the patient's skin. When there is an opening of the ureter either the ureters are brought to the skin in the abdomen or the ureters are attached to a Connected section of the small intestine, which in turn is led to the outside of the skin (. Ileum conductor). With the stoma a connection is created between the inside of the organ and the outside, whereby different.? Body fluids can pass through. Therefore, the patient must have a collection container for these secretions after the operation of the body, for example a pouch attached to the stoma. It is also important that a seal between the patient's skin and the

Collecting container is available. In particular because of the Because of the deleterious nature of the materials passing through the stoma, it is desirable that none of these materials penetrates through the seal as the materials attack the skin if they come into repeated contact with it come. The bag or collecting container shown in Fig. 1 is made of flexible, water-impermeable Material, such as polyethylene or polypropylene film material made with spaced apart walls 11 and 12, which are preferably heat-sealed at their edges, as shown at 13. An opening 14 is made at a suitable location on the front wall 11. Addicted The size of the opening varies from the particular stoma and can, for example, from 12 to 65 mm in diameter be.

With respect to the small intestine container according to FIG. 3 is the Pouch is generally shaped in the same way, although its shape can change, and usually is at its A device attached to the underside in order to carry out an emptying of the dispensed material. In this way the bag can be left on for several days. In the embodiment according to FIG. 3, the bag a narrow lower portion 20, the end 21 of which is open, but by the flexible clip 23 attached to it is attached, locked and can be grounded. In use, the lower portion 20 is rolled up and the flexible clip 23 is bent over in a known manner in order to close the exit opening 21. Here is the same an opening 14 is provided.

To attach the device to the body, an adhesive seal must be provided ^^ ferden. Here is a thin strip of material 25 is provided, which consists of a liquid-resistant, hydrophobic material, as described above, exists. The material is quite thin, generally less than 1.27mm, preferably by 0.25mm, however it can

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down to 0.025 strength. The highly elastic, adhesive rubber material, which is described in more detail below is attached to the fabric backing 25 and is designated by 26 in FIG. 2. Here the material is about 0.25 to 1.27 mm thick appropriate. A heat seal of the seal 26 and the backing 25 can be carried out directly through the sealing material and a firm, secure weld is obtained, as shown at 27.

To protect the seal 26 from use is a thin layer of peelable material such as paper or film 28 is placed over the seal and adhered this. This protects the seal during storage and prevents access to dust or other foreign matter prevented. The film is grasped by a free edge and easily peeled off and prior to application of the device thrown away.

The polyisocyanates used to make the sealing composition according to the present invention are described by the formula R (NCO) n, where η at least equals 2 and R is the connecting group of aliphatic, alicyclic, aliphatic-alicyclic, aromatic or aliphatic-aromatic hydrocarbons represents.

Examples of commercially available polyisocyanates that can be used are liquid isocyanates or polymers Isocyanates based on 4,4'-methyldiphenyl diisocyanates such as Up-John Company Isonate 143L, JpJohn Company PAPI 901, Mofcay Chemical Corporation Mondur CD un-i Mcbay Chemical Corporation Mondur MRS-IO.

The commercially available polyoxyalkylene polyols that are used in can be used to carry out the invention,

include Niax Polyol-PPG-3025 (Union Carbide Corporation ', Poly-G 55-37 (Olin Chemicals), Poly-G 85-28 i'Olir. Chemicals), and Multranol 3901 (Mobay Chemical Corporation) .

Preferred polycycles are Union Carbide Niax Polyol-PPG-3025 and Mobay Multranol 3901. As preferred polyisocyanate UpJohn Company! senate 143L is used.

The proportions and molecular weights of the polyoxyalkylene polyols used, likewise the amounts of hydrophilic fillers depend on the desired properties of the end product certainly. Therefore, as desired, end products can be made covering a wide range of Have properties such as adhesiveness, breathability, cohesiveness and the like.

For example ergiot an elastomer matrix composition from a glycol portion with nominal equivalent weights 1500 and triolein portions with nominal equivalent weights of 2000, in a ratio of about 4: 1 (in equivalents) of glykoi to triolein, is a particularly desirable one A product for an artificial orifice seal comprising a filler incorporated therein such as hydroxyethyl cellulose, hydropropyl cellulose or mixtures thereof, in the range from about 20 to 50 Has weight percent of the final plastic composition.

It has been found that the use of hydroxyethyl cellulose and products is much more breathable Hydroypropyl cellulose are obtained as, for example, when using iiatrium carboxymethyl cellulose, Sterkulin gum or polyelectrolytes based on Polyacrylamide.

In the manufacture of the breathable elastomeric materials according to the invention, the polyol components are with the hydrophilic filler or fillers mixed to form a homogeneous mixture, the consistency of which can range from a thin cream to that of a paste. The mixture will then react with subject to the polyisocyanate content. Methods such as a "one-shot" or a prepolymer reaction can be used will.

In the prepolymer reaction process, the polyol portion is subjected to a reaction with the isocyanate for a longer period of time To obtain chains that have NCO groups at the end, which can later react with other polyol components. This in part determines the physical properties of the resulting plastic composition.

For example, the elastomeric matrix product tends to to become harder and less conformable with increasing cross-link density of the structure, for example with higher functional polyol and / or NCO components. This physical Properties are also shown when the molecular weight the proportion of polyol is reduced. Conversely, the composition becomes lighter and weaker with enlargement the molecular weight of the polyol portion.

In addition, stoichiometric ratios influence this End product as described below. If the NCO / OH ratio is increased, there is a reduction in Conformability and adherence, while decreasing the Ratio of iiCO / OH a product with increased Adhesion but reduced strength.

The reaction is catalyzed with catalysts known for such reactions. Suitable catalysts include organic tin esters such as dibutyltin laurate, tertiary amines, and other catalysts well known to those skilled in the art.

In addition, a suitable foam generator such as Dew Corning Antifoam B uses v / ground to ensure uniformity To influence the flow and the formation of the resulting plastic compositions.

Many suitable adhesive compositions can pass through small changes in the amounts of substances used can be obtained. The following examples explain the invention closer.

Example 1:

35.0 g (0.0233 equivalents) Union Carbide Niax Polyol-PPG-3025 (1500 equivalent weights (EW) polyether glycol) and 11.0 g (0.0055 equivalents) Mobay Multranol 3901 (2000 EW polyether triolein) were mixed with 2 drops of M. & T Chemical Catalyst T-12; .dibutyltin laurate) and 1 drop of Dc--. ' Corning Antifoam B (silicone foam generator) mixed. 24.0 g of Hercules Natrosol 250 HHR ^{Hydroxyäthylz rt} llulose were added to this mixture to form a smooth, homogeneous, creamy liquid.

Then 4.2 g (0.0292 equivalents) of UpJchn Isonate 143L (liquid isocyanate based on 4,4 'methyldiphenyl diisocyanate) added and the mixture mixed thoroughly for 60 to 90 seconds, after which it was poured into a open, 3.18 mm deep layer mold made of silicone release paper was given. The mix was cured for 1 hour at room temperature until it settled and then cured further at 45 ° C.

The resulting product was a soft, flexible, adhesive elastomer of light yellow color and high elasticity and adaptability. It's breathable and very resistant to body fluids. This combination of properties is ideal for Use as a barrier for artificial orifices.

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Example 2:

The procedure described in Example 1 was repeated with the omission of the silicone foaming agent became. The resulting product was identical to that of Example 1.

Example 3:

The procedure of Example 1 was repeated using 28.8 g (0.0192 equivalents) of PPG-3025 and 19.2 g (0.0096 equivalents) Multranol 3901.

The resulting product was similar to that of Example 1, but somewhat lower in adhesion and in the Elasticity.

Example 4:

The procedure of Example 1 was repeated using 21.6 g (0.0144 equivalents) of FPG-3025 and 28.8 g (0.0144 equivalents) of Multranol 3901.

The produced product had lower adhesiveness and elasticity than that of Example 3.

Example 5:

The procedure of Example i was repeated using 43.2 g (0.0288 equivalents) of PPG-3025 and without Multranol 3901, but with 40 drops of catalyst T-12.

The final product produced was extremely adhesive and soft, had crystallization and was not for a seal suitable for artificial body orifices.

Example 6:

The procedure of Example 1 was repeated without PPG-3025 using 57.6 g, 0288 equivalents) Multranol 3901.

The resulting end product cracks easily and has minor Conformability and adherence to what makes it not; as Seal is suitable for body orifices.

Example 7:

The procedure of Example 1 was carried out using 36.4 g (0.0243 equivalents) of PPG-3025 and 9.0 g (0.0045 equivalents) of Multranol 3901 repeated.

The resulting product was very soft and adhesive a slight tendency to crystallize.

Example 8:

The procedure of Example 1 was repeated using 11.7 grams (0.0233 equivalents) of Quaker Oats Polymeg 1000 (500 EW polytetramethylene ether glycol) and 11.0 g (0.0055 equivalents) Multranol 3901.

The resulting product had less adaptability,

lower adhesion and lower elasticity as well as lower tear strength than that according to example 1 manufactured.

Example 9:

The procedure according to Example 1 was repeated under Use of 13.0 g Hercules Klucel HF hydroxypropyl cellulose instead of Natrosol.

The resulting end product was better than that prepared according to Example 1, but otherwise similar.

Example 10:

The procedure of Example 1 was repeated using 16.0 g of Natrosol 250 HHR and 8.0 Klucel HF.

The resulting final product was lighter in color as in Example 1, but otherwise of similar properties.

Example 11:

The procedure of Example 1 was repeated using an initial curing at 45 ° C for 15 Minutes to allow the material to set, followed by an "overnight curing" at room temperature.

The resulting product is similar to that of Example 1.

Example 12:

A prepolymer was prepared by mixing 35.0 g (0.0233 equivalents) of PPG-3025 with 11.0 g (0.0055 equivalents) of Multranol 3901 and drying the mixture at 100 to HO ⁰ C under a vacuum of 762 Torr ( abs.) (30 in. Hgabs.).

8.4 g (0.0584 equivalent) of Isonate 143L was slowly added with thorough mixing and heating the mixture to a temperature of 95 ⁰ C kept under nitrogen with occasional mixing for four hours. The mixture was then set aside under a nitrogen blanket at room temperature until the following day, whereupon a homogeneous mixture of:
35.0 g (0.0233 equivalents) PPG-3025,
11.0 g OK, 0055 equivalents) Multranol 3901,
4 drops of T-12 (dibutyltin dilaurate),
2 Trcpfen Antifoam B, and
43.0 grams of Natrosol 250 HHR

was admitted. The mixture was thoroughly 60 to 90 Seconds mixed uni in a sheet form ", as in Example 1, at room temperature for 1 hour and then at Cured 45 "C overnight.

The resulting end product was identical to me accordingly Example 1 obtained.

Example 13:

It has a quasi-prepolymer prepared by mixing 10 g (0.0694 equivalent) of Isonate 143L in 10 g (0.0066 equivalents) of PPG-3025 (previously abs at 100 to LiG ^c 'C under vacuum at 762 torr (.) (30 in. Hgabs.) Dried). The mixture was kept for 4 hours under stick portion at 95 ^W C with regular mixing, after which it was set aside under a nitrogen cover at room temperature until the following day.

Then 8.4 g of the quasi-prepolymer were added to a homogeneous mixture of the following substances:
30.8 grams (0.0205 equivalents) of PPG-3025
11.0 g (0.0055 equivalents) Multranol 3901,
4 drops of T-12,
2 drops of Antifoam B,
24.0 grams of Natrosol 250 HHR.

The mixture was mixed thoroughly for 60 to 90 seconds and then placed in a sheet mold as in FIG Example 1, cured at room temperature for 1 hour and further cured at 45 ° C overnight.

The resulting product was the same as that made in Example 1.

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Claims (16)

• Ο · O »" · ♦ = β "STRASSE & STOFFREGEN 3 3 25299 Patent Attorneys · European Patent Attorneys Dipl.-Ing. Joachim Stresse, some. Dlpl.-Phye. Dc. Hans-Herbert Stoffregen, Hanau Zvceibrückenetralie IS · D-8OOO Munich 8 (across from the patent office). Telephone (Οββ) 22 2β Ββ ■ Telex 0 22 0B4 CR. Bard, Inc. Munich, July 15, 1983 Murray Hill, N.J. 07974 (V.St.A.) 14 336 Bag with integrated breathable seal for artificial body openings claims 1. Bags for artificial orifices,
marked by
a front (11) with a stoma opening (14), a pad (25) of hydrophobic material welded to the front wall (11) and surrounding the opening (14), a skin barrier seal (26) on the exposed side of the pad ( 25), the skin barrier seal (26) being a polymeric composition of a non-aqueous reaction product of an organic polyisocyanate and a polyoxyalkylene polyol component, in which a hydrophilic filler is incorporated before the reaction of the polyisocyanate and the polyol, and in the resulting polymeric matrix the hydrophilic filler is physically encapsulated. 2. Bag for artificial orifices according to claim 1, ■ characterized , that the hydrophobic base (25) is a liquid-resistant Material is. 3. Bag for artificial orifices according to claim 1, characterized in that that the polymeric composition is a reaction product of an organic polyisocyanate of the general formula R (NCO) n where R denotes a polyoxyalkylene and η is at least 2, the polyol being a composition of polyols, and by incorporating a hydrophilic filler into the polyol portion the reaction of the polyisocyanate and the polyol to form a polymeric matrix with physical encapsulation of the hydrophilic filler is provided in the polymeric matrix. 4. bag for artificial orifices according to claim 3, characterized in that that the polyol is composed of glycols of nominal equivalent weights of 1500 and triolines of nominal equivalent weights of 2000 consists of about a 4: 1 ratio of glycol to triolein. 5. bag for artificial body orifices according to claim 1, characterized in that that the Pclyisocyanat is a liquid isocyanate based on 4,4 'methyldiphenyldiisocyanate and that Polyol a mixture of 1500 equivalent weight polyether glycol and 2000 equivalent weight polyether triolein is. 6. polymeric composition for use in contact with the skin, marked by a reaction product of an organic polyisocyanate and a polyoxyalkylene polyol portion, prior to reaction of the polyisocyanate and the polyol, a hydrophilic filler is incorporated into the polyol portion and a polymeric matrix is provided in which the hydrophilic filler is physically in the polymeric Matrix is encapsulated. 7. Polymeric composition adapted for use in contact, marked by
a reaction product of an organic polyisocyanate of the general formula R (NCO) η where R is independently from the class of aliphatic, alicyclic, aliphatic-alicyclic, aromatic or aliphatic-aromatic hydrocarbon compounds and η is at least 2, and a polyoxyalkylene polyol portion of the general formula R (0H) n where R is a polyoxyalkylene and η is at least 2, the polyol also being a combination of Can be polyols, and before reaction of the polyisocyanate and the polyol in the polyol portion hydrophilic filler is incorporated and a polymeric matrix is provided in which the hydrophilic filler is physically encapsulated in the polymeric matrix. 8. Polymeric composition according to claim 6,
characterized, that the polyol is comprised of glycol of nominal equivalent weights of 1500 and triolines of nominal equivalent weights of 2000 consists of about a 4: 1 ratio of glycol to triolein. 9. Polymeric composition according to claim 6,
characterized, that the polyisocyanate is a 4,4 'methyldiphenyl diisocyanate based liquid isocyanate and the polyol is a mixture of polyether glycol Equivalent weight 1500) and polyether triolein (equivalent weight 2000). 10. Polymeric composition for use as a sealant for devices for artificial body orifices in contact with the skin,
marked by a reaction product of an organic polyisocyanate and a polyoxyalkylene polyol moiety, wherein before the polyisocyanate of the polyol reacts, a hydrophilic filler is incorporated into the polyol component and a polymeric matrix is provided in which the hydrophilic filler is in the polymeric Matrix is physically encapsulated. 11. A process for the preparation of a polymeric composition for use in contact with the skin,
marked by Reaction of an organic polyisocyanate and one Polyoxyalkylene polyol, with a hydrophilic filler in before reaction of the polyisocyanate and polyol the polyol portion is incorporated and a polymeric matrix is formed in which the hydrophilic filler is physically encapsulated in the polymeric matrix. 12. A process for the preparation of a polymeric composition adapted for use in contact with the skin,
marked by Reaction of an organic polyisocyanate of the general formula R (NCO) n where R is independently selected from the group of aliphatic, alicyclic, aliphatic-alicyclic, aromatic or aliphatic-aromatic hydrocarbon compounds is selected and η is at least 2, with a polyoxyalkylene polyol portion of the general formula R (OH) n where R is a polyoxyalkylene and η is at least 2, the polyol being a combination of May be polyols, and incorporating a hydrophilic filler into the polyol portion prior to the reaction of the Polyisocyanate and the polyol, a polymeric matrix being formed in which the hydrophilic filler is physically encapsulated in the polymeric matrix. 13. A method of making a polymeric composition for the use of a sealant for devices for artificial body orifices in contact with the skin, marked by Reaction of an organic polyisocyanate and a polyoxyalkylene polyol, in which prior to reaction of the Polyisocyanate and the polyol, a hydrophilic filler is incorporated and a polymeric matrix is generated in which the hydrophilic filler is physically encapsulated in the polymeric matrix. 14. A method of making a polymeric composition for use as a sealant in devices for artificial body openings in contact with the skin, marked by
Reaction of an organic polyisocyanate of the general formula R (NCOJn where R is independently selected from the group of aliphatic, alicyclic, aliphatic-alicyclic, aromatic or aliphatic-aromatic hydrocarbon compounds and η is at least 2, with a polyoxyalkylene polyol portion of the general formula R (0H) n where R is a polyoxyalkylene and η is at least 2, the polyol being a combination of Polyclen can be, and incorporation of a hydrophilic filler in the polyol portion before the reaction Polyisocyanate and the polyol, and generating a polymeric matrix in which the hydrophilic filler is in physically encapsulated in the polymer matrix. 15. The method according to claim 11, characterized,
that the polyol consists of glycol of nominal equivalent weight of 1500 and triolein of nominal equivalent weight of 2000 in a ratio of about 4: 1 of glycol to triolein. 16. Polymeric composition according to claim 11, characterized,
that the polyisocyanate is a 4,4'-methyldiphenyl diisocyanate based liquid isocyanate and the polyol is a mixture of polyether glycol of equivalent weight 1500 and polyether triolein of equivalent weight 2000.