DE3272283D1 - A process for preparing chromans - Google Patents

A process for preparing chromans

Info

Publication number
DE3272283D1
DE3272283D1 DE8282302189T DE3272283T DE3272283D1 DE 3272283 D1 DE3272283 D1 DE 3272283D1 DE 8282302189 T DE8282302189 T DE 8282302189T DE 3272283 T DE3272283 T DE 3272283T DE 3272283 D1 DE3272283 D1 DE 3272283D1
Authority
DE
Germany
Prior art keywords
chromans
preparing
preparing chromans
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282302189T
Other languages
English (en)
Inventor
Yoji Sakito
Gohfu Suzukamo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Application granted granted Critical
Publication of DE3272283D1 publication Critical patent/DE3272283D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/562—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/28—Quinones containing groups having oxygen atoms singly bound to carbon atoms with monocyclic quinoid structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
DE8282302189T 1981-04-30 1982-04-28 A process for preparing chromans Expired DE3272283D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56066681A JPS57183782A (en) 1981-04-30 1981-04-30 Preparation of coumarone compound

Publications (1)

Publication Number Publication Date
DE3272283D1 true DE3272283D1 (en) 1986-09-04

Family

ID=13322908

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282302189T Expired DE3272283D1 (en) 1981-04-30 1982-04-28 A process for preparing chromans

Country Status (4)

Country Link
US (1) US4424389A (de)
EP (1) EP0065368B1 (de)
JP (1) JPS57183782A (de)
DE (1) DE3272283D1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3309159A1 (de) * 1983-03-15 1984-09-20 Basf Ag, 6700 Ludwigshafen Neue optisch aktive chromanderivate, verfahren zu deren herstellung sowie neue zwischenprodukte
DK170773B1 (da) * 1983-06-21 1996-01-15 Hoffmann La Roche Fremgangsmåde til fremstilling af d-alfa-tocopherol
DK401287A (da) * 1986-08-25 1988-02-26 Hoffmann La Roche Fremgangsmaade til fremstilling af opstisk aktive forbindelser
US5233056A (en) * 1990-01-18 1993-08-03 Asahi Denka Kogyo K.K. Optically active chroman derivatives and intermediates thereof, and process for manufacturing same
US5262552A (en) * 1990-02-20 1993-11-16 Asahi Denka Kogyo K.K. Optically active compounds and intermediates thereof, and process for manufacturing same
US6700001B2 (en) 2001-10-05 2004-03-02 Wyeth Process for stereoselective synthesis of 2-hydroxymethyl chromans
BR0213030A (pt) * 2001-10-05 2004-10-05 Wyeth Corp Processo estereoespecìfico para a sìntese de derivados de 2-il cromano
EP2471530B1 (de) 2005-06-01 2017-01-11 Edison Pharmaceuticals, Inc. Redoxaktive therapeutik zur behandlung von mitochondrialen erkrankungen und anderen zuständen sowie modulation von energie-biomarkern
EP2332534B1 (de) * 2006-02-22 2018-11-14 Bioelectron Technology Corporation Phenol- und Benzoquinonederivate zur Verwendung in der Behandlung von Mitochondriopathien und zur Modulation von Energie-Biomarkern
JP5374162B2 (ja) 2006-02-22 2013-12-25 エジソン ファーマシューティカルズ， インコーポレイテッド ミトコンドリア病および他の症状の処置のためのレドックス活性化治療の側鎖変異体およびエネルギーバイオマーカーの調節
US8952071B2 (en) 2008-01-08 2015-02-10 Edison Pharmaceuticals, Inc. (Het)aryl-p-quinone derivatives for treatment of mitochondrial diseases
CA2736250C (en) 2008-09-10 2016-12-20 Edison Pharmaceuticals, Inc. Treatment of pervasive developmental disorders with redox-active therapeutics
CN113024369A (zh) 2015-12-17 2021-06-25 Ptc医疗公司 用于治疗氧化应急障碍的化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU77344A1 (de) * 1977-05-16 1979-01-19
US4113740A (en) * 1977-05-17 1978-09-12 Hoffmann-La Roche Inc. Synthesis of optically active vitamin E
US4153614A (en) * 1978-05-12 1979-05-08 Hoffmann-La Roche Inc. Synthesis of (S)-(+)-6-hydroxy-2,5,7,8-tetramethylchroman-2-methanol and intermediates therein
US4337346A (en) * 1978-11-02 1982-06-29 Sumitomo Chemical Company, Limited α-Hydroxyaldehyde and a process for preparing the same

Also Published As

Publication number Publication date
JPS57183782A (en) 1982-11-12
US4424389A (en) 1984-01-03
EP0065368B1 (de) 1986-07-30
JPS6154795B2 (de) 1986-11-25
EP0065368A1 (de) 1982-11-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee