DE3264461D1 - 1-dodecylazacycloheptan-2-one used in anti-inflammatory compositions - Google Patents

1-dodecylazacycloheptan-2-one used in anti-inflammatory compositions

Info

Publication number
DE3264461D1
DE3264461D1 DE8282100275T DE3264461T DE3264461D1 DE 3264461 D1 DE3264461 D1 DE 3264461D1 DE 8282100275 T DE8282100275 T DE 8282100275T DE 3264461 T DE3264461 T DE 3264461T DE 3264461 D1 DE3264461 D1 DE 3264461D1
Authority
DE
Germany
Prior art keywords
dodecylazacycloheptan
inflammatory compositions
inflammatory
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282100275T
Other languages
German (de)
English (en)
Inventor
Eric L Nelson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NELSON, ERIC L., DR., NEWPORT BEACH, CALIF., US
Original Assignee
Nelson Research and Development Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nelson Research and Development Co filed Critical Nelson Research and Development Co
Application granted granted Critical
Publication of DE3264461D1 publication Critical patent/DE3264461D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08—Oxygen atoms
    • C07D223/10—Oxygen atoms attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
DE8282100275T 1981-01-23 1982-01-15 1-dodecylazacycloheptan-2-one used in anti-inflammatory compositions Expired DE3264461D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/227,628 US4310525A (en) 1981-01-23 1981-01-23 Method of treatment of inflammation

Publications (1)

Publication Number Publication Date
DE3264461D1 true DE3264461D1 (en) 1985-08-08

Family

ID=22853839

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282100275T Expired DE3264461D1 (en) 1981-01-23 1982-01-15 1-dodecylazacycloheptan-2-one used in anti-inflammatory compositions

Country Status (5)

Country Link
US (1) US4310525A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0060970B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS57142918A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU550564B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3264461D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4525199A (en) * 1981-05-04 1985-06-25 Nelson Research & Development Co. Method of improved pest control
US4422970A (en) * 1982-05-20 1983-12-27 Nelson Research & Development Company Method of synthesis of 1-dodecylazacycloheptan-2-one
US4762549A (en) * 1982-09-30 1988-08-09 Nelson Research & Development Co. Delivery of plant growth regulators
AU599964B2 (en) * 1986-01-31 1990-08-02 Nelson Research & Development Company Topical pharmaceuticals dye compositions, and plant nutrient compositions comprising 1-substituted azacycloalkanes as penetration enhancers
US5204339A (en) * 1986-01-31 1993-04-20 Whitby Research, Inc. Penetration enhancers for transdermal delivery of systemic agents
US4992422A (en) * 1986-01-31 1991-02-12 Whitby Research, Inc. Compositions comprising 1-substituted azacycloalkanes
US5256647A (en) * 1986-01-31 1993-10-26 Whitby Research, Inc. Compositions comprising 1-substituted azacycloalkanes
US5142044A (en) * 1986-04-23 1992-08-25 Whitby Research, Inc. Penetration enhancers for transdermal delivery of systemic agents
CA1319613C (en) * 1986-10-07 1993-06-29 Gevork Minaskanian Penetration enhancers for transdermal delivery of systemic agents
US4879275A (en) * 1987-09-30 1989-11-07 Nelson Research & Development Co. Penetration enhancers for transdermal delivery of systemic agent
US4920101A (en) * 1987-09-30 1990-04-24 Nelson Research & Development Co. Compositions comprising 1-oxo- or thiohydrocarbyl substituted azacycloaklkanes
ATE165597T1 (de) * 1992-01-20 1998-05-15 Sanol Arznei Schwarz Gmbh 1-oleoylazacycloheptanon(2) enthaltende arzneimittel zur verstärkung des transports durch biologische membranen
US6284754B1 (en) 1992-01-20 2001-09-04 Schwarz Pharma Ag Pharmaceutical compositions containing 1-oleylazacycloheptan-2-one as enhancing agent of transport across biological membranes
ATE555656T1 (de) * 2005-08-19 2012-05-15 Univ California Verwendung von seh-hemmern als analgetika
CN102516173B (zh) * 2011-12-16 2013-08-21 湖北南星化工总厂 一种月桂氮卓酮的合成方法
US10813894B2 (en) 2015-02-20 2020-10-27 The Regents Of The University Of California Methods of inhibiting pain

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1553310A (en) * 1975-06-19 1979-09-26 Nelson Res & Dev Vehicle composition containing 1-substituted azacycloalkan-2-ones
US3989816A (en) * 1975-06-19 1976-11-02 Nelson Research & Development Company Vehicle composition containing 1-substituted azacycloheptan-2-ones
US4323558A (en) * 1979-09-10 1982-04-06 Nelson Research & Development Co. Topical trien containing pharmaceutical compositions and methods of use

Also Published As

Publication number Publication date
JPS57142918A (en) 1982-09-03
EP0060970B1 (en) 1985-07-03
AU7976882A (en) 1982-07-29
AU550564B2 (en) 1986-03-27
JPH042571B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1992-01-20
EP0060970A1 (en) 1982-09-29
US4310525A (en) 1982-01-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NELSON, ERIC L., DR., NEWPORT BEACH, CALIF., US

8339 Ceased/non-payment of the annual fee