DE3173632D1 - Derivatives of iodothyronine compounds and their use in an assay for the free iodothyronine compounds - Google Patents

Derivatives of iodothyronine compounds and their use in an assay for the free iodothyronine compounds

Info

Publication number
DE3173632D1
DE3173632D1 DE8181304175T DE3173632T DE3173632D1 DE 3173632 D1 DE3173632 D1 DE 3173632D1 DE 8181304175 T DE8181304175 T DE 8181304175T DE 3173632 T DE3173632 T DE 3173632T DE 3173632 D1 DE3173632 D1 DE 3173632D1
Authority
DE
Germany
Prior art keywords
compounds
iodothyronine
assay
derivatives
iodothyronine compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181304175T
Other languages
English (en)
Inventor
Gavin Murray Cree
Terence Arthur Wilkins
Reginald Monks
David Peter Nowotnik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Clinical Diagnostics Ltd
Original Assignee
Amersham International PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham International PLC filed Critical Amersham International PLC
Application granted granted Critical
Publication of DE3173632D1 publication Critical patent/DE3173632D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE8181304175T 1981-09-11 1981-09-11 Derivatives of iodothyronine compounds and their use in an assay for the free iodothyronine compounds Expired DE3173632D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP81304175A EP0073865B1 (de) 1981-09-11 1981-09-11 Iodthyronin-Derivate und ihre Anwendung zur Bestimmung freier Iodthyronin-Verbindungen

Publications (1)

Publication Number Publication Date
DE3173632D1 true DE3173632D1 (en) 1986-03-13

Family

ID=8188391

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8181304175T Expired DE3173632D1 (en) 1981-09-11 1981-09-11 Derivatives of iodothyronine compounds and their use in an assay for the free iodothyronine compounds
DE1981304175 Pending DE73865T1 (de) 1981-09-11 1981-09-11 Iodthyronin-derivate und ihre anwendung zur bestimmung freier iodthyronin-verbindungen.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE1981304175 Pending DE73865T1 (de) 1981-09-11 1981-09-11 Iodthyronin-derivate und ihre anwendung zur bestimmung freier iodthyronin-verbindungen.

Country Status (2)

Country Link
EP (1) EP0073865B1 (de)
DE (2) DE3173632D1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA832844B (en) * 1982-05-18 1984-03-28 Smithkline Beckman Corp Oligopeptide prodrugs
GB8317124D0 (en) * 1983-06-23 1983-07-27 Ekins R P Free ligand assay
DE3415818C1 (de) * 1984-04-27 1985-04-18 Henning Berlin Gmbh Chemie- Und Pharmawerk, 1000 Berlin Verfahren zur Bestimmung freier Substanzen in biologischen Fluessigkeiten
US4672028A (en) * 1984-05-23 1987-06-09 Icn Micromedic Systems, Inc. Compositions and method for simultaneous multiple array of analytes using radioisotope chelate labels
DE3727238A1 (de) * 1987-08-14 1989-02-23 Henning Berlin Gmbh Immunologisches bestimmungsverfahren zur bestimmung von hapteneigenschaften aufweisenden freien substanzen
WO1993020442A1 (en) * 1992-03-30 1993-10-14 Abbott Laboratories Reagents and methods for the detection and quantification of thyroxine in fluid samples
US5352803A (en) * 1992-03-30 1994-10-04 Abbott Laboratories 5(6)-methyl substituted fluorescein derivatives
US8083786B2 (en) 2003-05-22 2011-12-27 Medoc Ltd. Thermal stimulation probe and method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4040907A (en) * 1974-06-20 1977-08-09 Syva Company Iodothyronine enzyme conjugates
US4168207A (en) * 1977-08-03 1979-09-18 Syva Company TBG assay
US4352751A (en) * 1979-09-10 1982-10-05 Analytical Radiation Corporation Species-linked diamine triacetic acids and their chelates
US4366143A (en) * 1979-09-24 1982-12-28 Amersham International Public Limited Company Assay for the free portion of substances in biological fluids

Also Published As

Publication number Publication date
EP0073865B1 (de) 1986-01-29
DE73865T1 (de) 1983-07-21
EP0073865A1 (de) 1983-03-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8127 New person/name/address of the applicant

Owner name: AMERLITE DIAGNOSTICS LTD., AMERSHAM, BUCKINGHAMSHI

8128 New person/name/address of the agent

Representative=s name: LEDERER, F., DIPL.-CHEM. DR. KELLER, G., DIPL.-BIO