DE3172904D1 - New cephem compounds and processes for preparation thereof - Google Patents

New cephem compounds and processes for preparation thereof

Info

Publication number
DE3172904D1
DE3172904D1 DE8181106108T DE3172904T DE3172904D1 DE 3172904 D1 DE3172904 D1 DE 3172904D1 DE 8181106108 T DE8181106108 T DE 8181106108T DE 3172904 T DE3172904 T DE 3172904T DE 3172904 D1 DE3172904 D1 DE 3172904D1
Authority
DE
Germany
Prior art keywords
processes
preparation
cephem compounds
new cephem
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181106108T
Other languages
German (de)
Inventor
Takao Takaya
Hisashi Takasugi
Masayoshi Murata
Akiteru Yoshioka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3172904D1 publication Critical patent/DE3172904D1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
DE8181106108T 1980-08-11 1981-08-05 New cephem compounds and processes for preparation thereof Expired DE3172904D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8026112 1980-08-11
GB8100848 1981-01-12

Publications (1)

Publication Number Publication Date
DE3172904D1 true DE3172904D1 (en) 1985-12-19

Family

ID=26276517

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181106108T Expired DE3172904D1 (en) 1980-08-11 1981-08-05 New cephem compounds and processes for preparation thereof

Country Status (3)

Country Link
US (1) US4443444A (en)
EP (1) EP0045937B1 (en)
DE (1) DE3172904D1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1213882A (en) * 1982-03-04 1986-11-12 Jun Okumura Cephalosporins
US4563449A (en) * 1982-07-19 1986-01-07 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives
DE3330605A1 (en) * 1983-08-25 1985-03-14 Hoechst Ag, 6230 Frankfurt CEPHALOSPORINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION
GB8329030D0 (en) * 1983-10-31 1983-11-30 Fujisawa Pharmaceutical Co Cephem compounds
EP0210815A3 (en) * 1985-07-25 1988-04-20 Beecham Group Plc 6-beta-(alpha-etherified oxyimino)-acylamino penicillanic-acid derivatives, their preparation and use
DE3787030T2 (en) * 1986-04-14 1994-04-07 Banyu Pharma Co Ltd 1-CARBOXY-1-VINYLOXYIMINOAMINOTHIAZOLE-CEPHALOSPORINE DERIVATIVES AND THE PRODUCTION THEREOF.
JP6151257B2 (en) 2011-09-09 2017-06-21 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． Treatment of pulmonary infections
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
KR102226197B1 (en) 2013-03-15 2021-03-11 머크 샤프 앤드 돔 코포레이션 Ceftolozane antibiotic compositions
US20140274991A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane pharmaceutical compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
ES2800603T3 (en) 2013-09-09 2021-01-04 Merck Sharp & Dohme Treatment of infections with ceftolozane / tazobactam in patients with renal impairment
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
DE2715385A1 (en) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd CEPHALOSPORIN DERIVATIVES, THE PROCESS FOR THEIR MANUFACTURING AND MEDICINAL PRODUCTS CONTAINING THEM
JPS53144594A (en) * 1976-12-27 1978-12-15 Fujisawa Pharmaceut Co Ltd 3,7-di-substitued-3-cephem-4-carboxylic acid derivatives
DE2716677C2 (en) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephem derivatives and processes for their preparation
DE2714880A1 (en) * 1977-04-02 1978-10-26 Hoechst Ag CEPHEMDER DERIVATIVES AND PROCESS FOR THEIR PRODUCTION
AR228726A1 (en) * 1978-05-26 1983-04-15 Glaxo Group Ltd PROCEDURE FOR THE PREPARATION OF ANTIBIOTIC (6R, 7R) -7 - ((Z) -2- (2-AMINOTIAZOL-4-IL) -2- (2-CARBOXIPROP-2-OXIIMINO) ACETAMIDO) -3- (1- PIRIDINIOMETIL) CEF-3-EM-4-CARBOXILATO
US4332798A (en) * 1978-12-29 1982-06-01 Fujisawa Pharmaceutical Co., Ltd. 7-Amino-thia-diazole oxyimino derivatives of cephem and cephem compounds
NZ193212A (en) * 1979-03-22 1982-12-07 Glaxo Group Ltd Cephalosporin antibiotics and pharmaceutical compsitions
US4329453A (en) * 1979-10-02 1982-05-11 Glaxo Group Limited Cephalosporin antibiotic
US4336253A (en) * 1981-03-11 1982-06-22 Eli Lilly And Company Cephalosporin antibiotics

Also Published As

Publication number Publication date
EP0045937A3 (en) 1982-10-13
EP0045937A2 (en) 1982-02-17
EP0045937B1 (en) 1985-11-13
US4443444A (en) 1984-04-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee