DE2965917D1 - A process for the preparation of a solid sodium amoxycillin and aqueous solutions thereof - Google Patents

A process for the preparation of a solid sodium amoxycillin and aqueous solutions thereof

Info

Publication number
DE2965917D1
DE2965917D1 DE7979301705T DE2965917T DE2965917D1 DE 2965917 D1 DE2965917 D1 DE 2965917D1 DE 7979301705 T DE7979301705 T DE 7979301705T DE 2965917 T DE2965917 T DE 2965917T DE 2965917 D1 DE2965917 D1 DE 2965917D1
Authority
DE
Germany
Prior art keywords
preparation
aqueous solutions
solid sodium
sodium amoxycillin
amoxycillin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979301705T
Other languages
English (en)
Inventor
Charles Bernard Taskis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of DE2965917D1 publication Critical patent/DE2965917D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE7979301705T 1978-12-08 1979-08-21 A process for the preparation of a solid sodium amoxycillin and aqueous solutions thereof Expired DE2965917D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7847744 1978-12-08

Publications (1)

Publication Number Publication Date
DE2965917D1 true DE2965917D1 (en) 1983-08-25

Family

ID=10501603

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7979301705T Expired DE2965917D1 (en) 1978-12-08 1979-08-21 A process for the preparation of a solid sodium amoxycillin and aqueous solutions thereof

Country Status (6)

Country Link
US (1) US4316886A (de)
EP (1) EP0012496B1 (de)
JP (1) JPS5579387A (de)
AU (1) AU531634B2 (de)
DE (1) DE2965917D1 (de)
NZ (1) NZ191982A (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2503710B1 (fr) * 1981-04-10 1985-07-05 Bristol Myers Co Procede de production du sel de sodium de l'amoxicilline
US4898728A (en) * 1988-04-07 1990-02-06 Beecham Group P.L.C. Process for production of composition containing lecithin and polyvinylpyrrolidone
WO2000040220A1 (en) * 1999-01-06 2000-07-13 Korea Research Institute Of Chemical Technology Method of preparing pharmaceutical active ingredient comprising water-insoluble drug and pharmaceutical composition for oral administration comprising the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3634586A (en) * 1968-12-04 1972-01-11 Bristol Myers Co Stable aqueous suspensions of ampicillin
US3928566A (en) * 1970-08-14 1975-12-23 Du Pont Lyophilized biological products
JPS5418330B2 (de) * 1973-03-16 1979-07-06
GB1463563A (en) * 1974-10-10 1977-02-02 Beecham Group Ltd Pharmaceutical compositions
US4024240A (en) * 1975-07-18 1977-05-17 Eli Lilly And Company Antibiotic A-32390 compositions
US4018889A (en) * 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
GB1543317A (en) * 1976-08-04 1979-04-04 Beecham Group Ltd Process for the preparation of sodium amoxycillin

Also Published As

Publication number Publication date
US4316886A (en) 1982-02-23
AU531634B2 (en) 1983-09-01
EP0012496B1 (de) 1983-07-20
AU5228479A (en) 1980-06-12
JPS5579387A (en) 1980-06-14
NZ191982A (en) 1982-11-23
EP0012496A1 (de) 1980-06-25

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee