DE202022101545U1 - A medical device used to treat neurological disorders - Google Patents

Abstract

A system (100) for treating neurological disorders, comprising; A medical device (102) implanted subscalp or intracranial in a patient with a variety of neurological disorders, wherein an external programmer is placed at various neurological sites to treat multiple neurological disorders, characterized in that:
- a sensor (104) used by a medical device and capable of detecting a sensed event from the patient associated with at least one of the plurality of neurological disorders by sensing a condition on a sensor lead (112). ,
- a controller (106) responsive to a sensor and controlling a first therapy module (108) providing a first therapy output (114) and a second therapy module (110) providing a second therapy output (116), wherein it causes either the first therapy module or the second therapy module or both to operate in closed loop;
- the first therapy module (108) provides a first therapy output (114) and also provides a therapeutic output for a first neurological disorder;
the second therapy module (110) provides a second therapy output (116) and also provides a therapeutic output for a second neurological disorder;
wherein at least one of the first therapy module (108) and the second therapy module (110) is operatively coupled to the sensor (104) and is responsive to a sensed event from the patient;
wherein the second therapy module (110) via the sensor (104) either in the controller (106) by connecting the first (108) and the second therapy module (110) in one direction or by receiving direct feedback from either the first (108) or the second (110) therapy module or both.

Description

TECHNICAL AREA

The present disclosure relates to a medical device for treating neurological disorders.

BACKGROUND OF THE INVENTION

The background description contains information that may be useful in understanding the present invention. It does not constitute an admission that the information contained herein is prior art or relevant to the present invention, or that any publication expressly or implicitly referred to is prior art.

Nervous system problems, including neurological disorders, affect millions of people, leading to mortality and reduced quality of life. Central nervous system disorders, peripheral nervous system disorders, and mental and psychiatric problems are all examples of nervous system disorders. Epilepsy, Parkinson's disease, essential tremor, dystonia and multiple sclerosis are just a few examples of such diseases (MS). Anxiety disorders (such as generalized anxiety, panic disorder, phobias, post-traumatic stress disorder (PTSD), and obsessive-compulsive disorder), mood disorders (such as major depression, bipolar depression, and dysthymic disorder), sleep disorders (narcolepsy), obesity, and anorexia) are examples of nervous system disorders, some of which Millions of people are affected.

Change Information

For example, epilepsy is the most common serious neurological disorder worldwide. Various solutions for early risk assessment have been developed in the relevant prior art and NPL sources. Reference patent literature on the prior art for neurological diseases and brain disorders is given below.

US20190054262A1 , 2008 Systems for facilitating intranasal treatment of a patient's sphenopalatine/pterygopalatine cavity are disclosed. The system is also suitable for the treatment of acute pain conditions and is so sophisticated that it can be carried out by medical assistants, nurses and other well-trained practitioners. The device, in some embodiments, includes a sheath hub, a catheter hub, a locking member, and an engagement member. The engagement between the locking element and the engagement element prevents rotation of the sheath hub with respect to the catheter hub.

US9233258B2 , 2005, Apparatus and systems for the non-invasive treatment of medical conditions by delivering energy to target tissue are disclosed, comprising an electrical power source, a magnetically permeable toroidal core, and a coil wound around the core. The coil and core are embedded in a continuous, electrically conductive medium that is shaped to conform to the contour of an arbitrarily oriented target body surface of a patient. The conductive medium is applied to this surface by any of the various methods disclosed, and the power source delivers a pulse of electrical charge to the coil such that the coil induces an electrical current and/or an electrical field in the patient, causing tissue and/or one or several nerve fibers in the patient are stimulated. The invention forms an elongate electric field of action that can be aligned parallel to a long nerve. In one embodiment, the device comprises two toroidal cores lying side by side.

US20210275815A1 , 2005, Method and apparatus for improving a human's cognitive function. The invention utilizes an implanted device, such as an implantable signal generator or pump, to affect tissue elements within a human brain's Papez circuit, as well as tissues upstream or downstream of the Papez circuit. The implanted device performs treatment therapy so as to improve human cognitive function. A sensor can be used to detect various symptoms of cognitive disorder. A microprocessor algorithm can then analyze the sensor's output to control the delivery of stimulation and/or drug therapy.

Treatment of nervous system problems can come in a variety of forms. Treatment methods may involve a variety of modalities, either alone or in combination, such as electrical stimulation, magnetic stimulation, drug infusion, and/or brain temperature regulation. A number of devices for the therapy of neurological diseases have already been described.

The above devices and methods are unique in that they all apply to the hand treatment of a single disease, even though multiple therapies can be used to treat that single disease. As a result, these devices and methods are ill-equipped and inadequately structured to treat or respond to multiple diseases in a single patient.

Therefore, the present disclosure overcomes the above-mentioned problem associated with the traditionally available methods or systems, and each of the above-mentioned inventions can be used with the presented technique with or without modification. Comorbidities include a wide range of neurological disorders. For example, people who suffer from migraine headaches are often also diagnosed with major depression. Epilepsy patients also suffer more frequently from clinical depression and severe headaches. Implantable medical devices have long been recognized as useful in the treatment of neurological disorders. However, many implanted medical devices are designed to treat a specific disease, leaving the concomitant disorder untreated or even forcing the patient to resort to unrelated medications. Embodiments of the present invention provide a medical device that can treat two or more neurological disorders simultaneously.

All research publications contained herein are incorporated by reference to the same extent as if each individual publication or patent application were expressly and individually identified as incorporated by reference. If any definition or use of a term in an incorporated reference is inconsistent or inconsistent with the definition of that term given herein, the definition of that term given herein shall control. Accordingly, in some embodiments, the numerical parameters set forth in the written description and appended claims are approximate and may vary depending on the desired properties to be achieved by a particular embodiment. The reciting of ranges of values herein is intended solely as a shorthand method to refer individually to each and every value that falls within the range. Unless otherwise noted herein, each individual value is included in the specification as if individually cited herein. All methods described herein can be performed in any suitable order, unless otherwise noted herein or otherwise clearly contradicted by context. The use of any examples or exemplary phrases (e.g., "like") provided with respect to particular embodiments herein is for the purpose of better elucidating the invention and does not constitute a limitation on the scope of the invention otherwise claimed. No language the specification should be construed as indicating a non-claimed element that is essential to the practice of the invention

OBJECTS OF THE INVENTION

The aim of the present disclosure is to provide a system for the treatment of neurological disorders.

SUMMARY OF THE INVENTION

The present concept of the invention is directed to the system for the treatment of neurological disorders. A medical device implanted under the scalp or in the skull in a patient with a variety of neurological disorders, with external programmers placed in different neurological locations for the treatment of multiple neurological disorders.

In one embodiment, at least one of the first therapy module and the second therapy module is operatively coupled to the sensor and is responsive to a sensed event from the patient.

In one embodiment, the second therapy module can be controlled via a sensor either by connecting the first and second therapy modules in one direction or by receiving direct feedback from either the first or second therapy module or both.

Although the present disclosure has been explained in relation to a particular group of functional modules, any other module or group of modules may be added/deleted/changed/combined and all such changes in the architecture/construction of the proposed system fall fully within the scope of the Scope of the present disclosure. Each module can also be broken down into one or more functional sub-modules, all of which also fall fully within the scope of the present disclosure.

Various objects, features, aspects and advantages of the subject invention will become more apparent from the following detailed description of preferred embodiments taken in conjunction with the accompanying drawings in which like numerals represent like components.

character list

• 1 zeigt ein beispielhaftes Blockdiagramm eines medizinischen Geräts zur Behandlung neurologischer Erkrankungen,

The accompanying drawing is included to provide a further understanding of the present disclosure and is incorporated into and constitutes a part of this specification. The drawings illustrate example embodiments of the present disclosure and, together with the description, serve to explain the principles of the present disclosure.

• 1 shows an exemplary block diagram of a medical device for the treatment of neurological diseases,

The accompanying drawing is provided for further understanding of the present disclosure and is a part of this specification. The drawings illustrate example embodiments of the present disclosure and together with the description serve to explain the principles of the present disclosure.

Other objects, advantages and novel features of the invention will be apparent from the following detailed description of the present embodiment when taken in connection with the accompanying drawing.

DETAILED DESCRIPTION OF THE INVENTION

In the following description, numerous specific details are set forth in order to provide a thorough understanding of the embodiments of the present invention. One skilled in the art will appreciate that embodiments of the present invention may be practiced without some of these specific details.

The embodiments of the present invention include various steps, which are described below. The steps may be performed by hardware components or may be contained in machine-executable instructions that can be used to cause a general purpose or special purpose processor programmed with the instructions to perform the steps. Alternatively, the steps may be performed by a combination of hardware, software, and firmware and/or by human personnel.

When the specification states that a component or feature "may", "may", "might" or "might be" included, it is not necessary for that component or feature to be included or to have the feature.

Although the present invention has been described in terms of control and surveillance for defense purposes, it should be understood that this has been done by way of example to illustrate the invention and any other purpose or function for which the structure or configuration described is suitable can be used falls within the scope of the present disclosure.

Exemplary embodiments are described in more detail below with reference to the accompanying drawings, in which exemplary embodiments are illustrated. However, this invention may be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. These embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those of ordinary skill in the art. Furthermore, all statements contained herein that describe embodiments of the invention, as well as specific examples thereof, are intended to include both structural and functional equivalents thereof. In addition, such equivalents are intended to include both currently known equivalents and equivalents developed in the future (i.e., any elements developed that perform the same function, regardless of structure).

The following is a detailed description of the embodiments of the disclosure illustrated in the accompanying drawings. The embodiments are detailed in order to clearly convey the disclosure. However, the length of detail is not intended to limit the foreseeable variations of embodiments; on the contrary, it is intended to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the present disclosure as defined by the appended claims.

Each of the appended claims defines a separate invention that is recognized for infringement purposes as equivalent to the various elements or limitations recited in the claims. Depending on the context, all references below to the “invention” may in some cases only refer to particular embodiments. In other instances, references to "invention" are to subject matter recited in one or more, but not necessarily all, claims.

Various terms used herein are listed below. To the extent that a term used in a claim is not defined below, it should be given the broadest definition available to persons on the relevant have given that term to the art as reflected in printed publications and issued patents at the time of filing.

In one embodiment of the present disclosure 1 an exemplary block diagram of a medical device (102) for treating neurological disorders. A system (100) for treating neurological disorders, comprising: a medical device (102) implanted in a patient having a variety of neurological disorders subscalp or intracranial, with an external programmer at various neurological sites for treatment multiple neurological disorders, characterized in that a sensor (104) used by the medical device is capable of detecting a sensed event from the patient associated with at least one of the plurality of neurological disorders, by detecting a condition on a sensor line (112); a controller (106) responsive to the sensor and driving a first therapy module (108) providing a first therapy output (114) and a second therapy module (110) providing a second therapy output (116), either causing the first therapy module or the second therapy module or both to operate in closed loop; the first therapy module (108) provides a first therapy output (114) and further provides a therapeutic output for a first neurological disorder; the second therapy module (110) provides a second therapy output (116) and further provides a therapeutic output for a second neurological disorder.

In one aspect of the present invention, wherein at least one of the first therapy module (108) and the second therapy module (110) is operatively coupled to the sensor (104) and is responsive to a sensed event from the patient.

In another aspect of the present invention, the second therapy module (110) can be controlled by the sensor (104) either in the controller (106), by connecting the first (108) and second therapy module (110) in one direction, or by receiving direct feedback performed by either the first (108) or second (110) therapy module or at the.

In one embodiment, the first and second therapy outputs can be electrical stimulation, drug infusion, heat transducers, or other therapeutic outputs.

In one embodiment, both the first therapy module (108) and the second therapy module (110) operate in open loop, i. H. without feedback control.

In one embodiment, either the first therapy module (108) and the second therapy module (110) can operate in closed-loop control to respond to a neurological event, i.e., with feedback control.

In one embodiment, the sensor (104) includes electrical signals, e.g. EEG or EKG, electrochemical feedback and motion sensors, e.g. B. Accelerometer.

In one embodiment, the first and second therapy outputs may be electrical stimulation, drug infusion, heat transducers, or other therapeutic outputs.

In one embodiment, a drug delivery module is included in the first therapy module (108) and the first output is delivery of a drug.

In one embodiment, the second therapy module (110) includes an electrical stimulator module, the second output having an electrical stimulation signal.

While the foregoing describes various embodiments of the present invention, other and further embodiments of the invention may be devised without departing from the basic scope of the invention. The scope of the invention is determined by the following claims. The invention is not limited to the described embodiments, variants or examples, which are included to enable a person of ordinary skill in the art to make and use the invention when combined with information and knowledge that the available to a person with ordinary expertise in the field of technology.

The present invention is not limited to the specific embodiments described above, and various modifications and variations are possible. All changes, equivalents, improvements and the like made to the above embodiments in accordance with the technical spirit of the present invention should be included in the scope of the present invention.

Thus, the scope of the present disclosure is to be defined by the appended claims and includes both combinations and sub-combinations of the various features described herein, as well as variations and modifications thereof that would occur to those skilled in the art upon reading the foregoing description. business data.

Reference List

100

A system for treating neurological disorders

102

Medical device

104

sensor

106

control

108

First therapy module

110

Second therapy module

112

sensor line

114

First therapy edition

116

Second therapy exit

QUOTES INCLUDED IN DESCRIPTION

This list of documents cited by the applicant was generated automatically and is included solely for the better information of the reader. The list is not part of the German patent or utility model application. The DPMA assumes no liability for any errors or omissions.

Patent Literature Cited

• US20190054262A1 [0005]
• US 9233258 B2 [0006]
• US20210275815A1 [0007]

Claims (8)

A system (100) for treating neurological disorders, comprising; A medical device (102) implanted subscalp or intracranial in a patient with a variety of neurological disorders with an external programmer placed at various neurological sites to treat multiple neurological disorders, characterized in that : - a sensor (104 ) used by a medical device and capable of detecting a sensed event from the patient associated with at least one of the plurality of neurological disorders by sensing a condition on a sensor line (112), - a controller ( 106) responsive to a sensor and controlling a first therapy module (108) providing a first therapy output (114) and a second therapy module (110) providing a second therapy output (116), either the first therapy module or causing the second therapy module or both to operate in closed loop; - the first therapy module (108) provides a first therapy output (114) and also provides a therapeutic output for a first neurological disorder; the second therapy module (110) provides a second therapy output (116) and also provides a therapeutic output for a second neurological disorder; wherein at least one of the first therapy module (108) and the second therapy module (110) is operatively coupled to the sensor (104) and is responsive to a sensed event from the patient; wherein the second therapy module (110) via the sensor (104) either in the controller (106) by connecting the first (108) and the second therapy module (110) in one direction or by receiving direct feedback from either the first (108) or the second (110) therapy module or both. System (100) for the treatment of neurological disorders claim 1 wherein the first and second therapy outputs may be electrical stimulation, drug infusion, heat transducers, or other therapeutic outputs. System (100) for the treatment of neurological disorders claim 1 wherein both the first therapy module (108) and the second therapy module (110) operate periodically, ie without feedback control, in open loop. System (100) for the treatment of neurological disorders claim 1 wherein either the first therapy module (108) or the second therapy module (110) can operate in a closed loop to respond to a neurological event, ie, with feedback control. System (100) for treating neurological disorders claim 1 wherein the sensor (104) comprises electrical signals, eg, EEG or EKG, electrochemical feedback, and motion sensors, eg, accelerometers. System (100) for the treatment of neurological disorders claim 1 wherein the first and second therapy outputs may be electrical stimulation, drug infusion, heat transducers, or other therapeutic output. System (100) for treating neurological disorders claim 1 wherein a drug delivery module is included in the first therapy module (108) and the first output is delivery of a drug. System (100) for the treatment of neurological disorders claim 1 wherein an electrical stimulator module is included in the second therapy module (110) and the second output comprises an electrical stimulation signal.

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