DE20111022U1 - Sample holder for the detection of biological or chemical species - Google Patents

Sample holder for the detection of biological or chemical species

Info

Publication number
DE20111022U1
DE20111022U1 DE20111022U DE20111022U DE20111022U1 DE 20111022 U1 DE20111022 U1 DE 20111022U1 DE 20111022 U DE20111022 U DE 20111022U DE 20111022 U DE20111022 U DE 20111022U DE 20111022 U1 DE20111022 U1 DE 20111022U1
Authority
DE
Germany
Prior art keywords
light
carrier
binding surfaces
standard data
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE20111022U
Other languages
German (de)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut fuer Physikalische Hochtechnologie eV
Original Assignee
Institut fuer Physikalische Hochtechnologie eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut fuer Physikalische Hochtechnologie eV filed Critical Institut fuer Physikalische Hochtechnologie eV
Priority to DE20111022U priority Critical patent/DE20111022U1/en
Publication of DE20111022U1 publication Critical patent/DE20111022U1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B01J2219/00536—Sheets in the shape of disks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/0061—The surface being organic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00646—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports
    • B01J2219/00648—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports by the use of solid beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00702—Processes involving means for analysing and characterising the products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof

Description

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßtThe description text was not recorded electronically

Claims (7)

1. Probenträger zum Nachweis biologischer oder chemischer Spezies bestehend aus einem planaren Träger (1), der mit einem in optisch auslesbaren Signalspuren (2) eingeschrieben Standarddatensatz derart versehen ist, daß eine wahlweise vorgebbare Anzahl von fixierten, optisch auslesbaren r-ϕ-Koordinaten (21) gebildet ist und die Trägeroberfläche weiterhin mit einer vorgebbaren Anzahl einzelner und voneinander zumindest im Raster des eingeschriebenen Standarddatensatzes beabstandeter und den r-ϕ-Koordinaten (21), oder eines Teils davon, mit definiert zugeordneten Bindungsflächen (3) versehen ist, deren jeweilige Bindungsselektivität in Abhängigkeit von den an sie zu bindenden Spezies (4), die mit einem reflektierenden oder lichtabsorbierenden oder lichtstreuenden Marker (5) versehen sind, vorgebbar ist, wodurch auf ausgewählten Bindungsflächen (31) reflektierende oder lichtabsorbierende oder Streulicht verursachende Spots gebildet sind.1.Sample carrier for the detection of biological or chemical species consisting of a planar carrier ( 1 ) which is provided with a standard data record inscribed in optically readable signal tracks ( 2 ) in such a way that an optionally definable number of fixed, optically readable r-ϕ coordinates ( 21 ) is formed and the carrier surface is further provided with a predeterminable number of individual and at least spaced from one another in the grid of the inscribed standard data set and the r-Koordinaten coordinates ( 21 ), or a part thereof, with defined assigned binding surfaces ( 3 ), the respective respective ones Binding selectivity as a function of the species ( 4 ) to be bound to them, which are provided with a reflective or light-absorbing or light-scattering marker ( 5 ), can be predetermined, whereby reflective or light-absorbing or scattering light-causing spots are formed on selected binding surfaces ( 31 ). 2. Probenträger nach Anspruch 1, dadurch gekennzeichnet, daß für den planaren Träger (1) mit dem eingeschriebenen Standarddatensatz eine an sich übliche CD oder ähnlicher Träger eingesetzt ist.2. Sample carrier according to claim 1, characterized in that a conventional CD or similar carrier is used for the planar carrier ( 1 ) with the inscribed standard data set. 3. Probenträger nach Anspruch 1, dadurch gekennzeichnet, daß für den planaren Träger (1) eine transparente Scheibe eingesetzt ist, die mit einer nichttransparenten Belegung versehen ist, wobei die Belegung im Bereich der vorgegebenen r-ϕ-Koordinaten des Standarddatensatzes entfernt ist.3. Sample carrier according to claim 1, characterized in that a transparent disc is used for the planar carrier ( 1 ), which is provided with a non-transparent assignment, the assignment being removed in the range of the predetermined r-Koordinaten coordinates of the standard data set. 4. Probenträger nach Anspruch 1, 2 oder 3, dadurch gekennzeichnet, daß auf den beabstandeten Bindungsflächen (3) unterschiedliche Oligonukleotide immobilisiert sind. 4. Sample carrier according to claim 1, 2 or 3, characterized in that different oligonucleotides are immobilized on the spaced binding surfaces ( 3 ). 5. Probenträger nach Anspruch 1, dadurch gekennzeichnet, daß für die Marker (5) lichtreflektierende metallische Partikel, insbesondere Goldpartikel, mit Durchmessern in der Größenordnung von 2 . . . 600 nm, vorzugsweise 15 . . . 60 nm, eingesetzt sind.5. Sample holder according to claim 1, characterized in that for the markers ( 5 ) light-reflecting metallic particles, in particular gold particles, with diameters in the order of 2. , , 600 nm, preferably 15. , , 60 nm, are used. 6. Probenträger nach Anspruch 1, dadurch gekennzeichnet, daß die Bindungsflächen (3) mit Durchmessern oder Längserstreckungen in der Größenordnung von 0,5 µm bis 500 µm festgelegt sind.6. sample carrier according to claim 1, characterized in that the binding surfaces ( 3 ) with diameters or longitudinal dimensions are in the order of 0.5 microns to 500 microns. 7. Probenträger nach Anspruch 6, dadurch gekennzeichnet, daß metallische Marker eingesetzt werden, welche an den jeweiligen Bindungsflächen selektiv ankoppeln, wobei die gebundenen Marker vor der optischen Auswertung einer stromlosen Metallbeschichtung unterworfen werden, um die Reflektivität der jeweiligen Bindungsflächen zu erhöhen.7. sample holder according to claim 6, characterized in that metallic markers are used, which on the respective Selectively couple binding surfaces, whereby the bound markers before the optical evaluation of an electroless metal coating be subjected to the reflectivity of each Increase bond areas.
DE20111022U 2000-07-01 2001-06-29 Sample holder for the detection of biological or chemical species Expired - Lifetime DE20111022U1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE20111022U DE20111022U1 (en) 2000-07-01 2001-06-29 Sample holder for the detection of biological or chemical species

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10033360 2000-07-01
DE20111022U DE20111022U1 (en) 2000-07-01 2001-06-29 Sample holder for the detection of biological or chemical species

Publications (1)

Publication Number Publication Date
DE20111022U1 true DE20111022U1 (en) 2001-10-04

Family

ID=7648329

Family Applications (1)

Application Number Title Priority Date Filing Date
DE20111022U Expired - Lifetime DE20111022U1 (en) 2000-07-01 2001-06-29 Sample holder for the detection of biological or chemical species

Country Status (1)

Country Link
DE (1) DE20111022U1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002048678A2 (en) * 2000-12-15 2002-06-20 The Rockefeller University High capacity and scanning speed system for sample handling and analysis
WO2002053777A2 (en) * 2000-12-29 2002-07-11 Picoliter Inc. Device and method for tracking conditions in an assay
WO2020125859A2 (en) 2018-12-20 2020-06-25 Leibniz-Institut Für Photonische Technologien E.V. Arrangement and method for identifying optical properties of a sample, in particular for selective detection of biological molecules and for selecting molecular occupancy

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002048678A2 (en) * 2000-12-15 2002-06-20 The Rockefeller University High capacity and scanning speed system for sample handling and analysis
WO2002048678A3 (en) * 2000-12-15 2003-02-06 Univ Rockefeller High capacity and scanning speed system for sample handling and analysis
WO2002053777A2 (en) * 2000-12-29 2002-07-11 Picoliter Inc. Device and method for tracking conditions in an assay
WO2002053777A3 (en) * 2000-12-29 2003-02-27 Picoliter Inc Device and method for tracking conditions in an assay
WO2020125859A2 (en) 2018-12-20 2020-06-25 Leibniz-Institut Für Photonische Technologien E.V. Arrangement and method for identifying optical properties of a sample, in particular for selective detection of biological molecules and for selecting molecular occupancy
DE102018133037A1 (en) 2018-12-20 2020-06-25 Leibniz-Institut für Photonische Technologien e. V. Arrangement and method for the detection of optical properties of a sample, in particular for the selective detection of biological molecules and for reading out a molecular assignment
DE102018133037B4 (en) * 2018-12-20 2021-02-25 Leibniz-Institut für Photonische Technologien e. V. Arrangement and method for detecting optical properties of a sample, in particular for the selective detection of biological molecules and for reading out a molecule occupancy

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Legal Events

Date Code Title Description
R207 Utility model specification

Effective date: 20011108

R150 Term of protection extended to 6 years

Effective date: 20040210

R151 Term of protection extended to 8 years

Effective date: 20070713

R158 Lapse of ip right after 8 years

Effective date: 20100101