DE19681115D2 - New 1-phenylalkyl / alkylene-4 - (. Alpha.-hydroxydiphenylmethyl) piperidine derivatives and their use as serotonin antagonists - Google Patents

New 1-phenylalkyl / alkylene-4 - (. Alpha.-hydroxydiphenylmethyl) piperidine derivatives and their use as serotonin antagonists

Info

Publication number
DE19681115D2
DE19681115D2 DE19681115T DE19681115T DE19681115D2 DE 19681115 D2 DE19681115 D2 DE 19681115D2 DE 19681115 T DE19681115 T DE 19681115T DE 19681115 T DE19681115 T DE 19681115T DE 19681115 D2 DE19681115 D2 DE 19681115D2
Authority
DE
Germany
Prior art keywords
hydroxydiphenylmethyl
phenylalkyl
alkylene
alpha
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19681115T
Other languages
German (de)
Inventor
Eckhart Pein
Helmut Ritter
Reinhard Laven
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DE19681115T priority Critical patent/DE19681115D2/en
Application granted granted Critical
Publication of DE19681115D2 publication Critical patent/DE19681115D2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DE19681115T 1995-12-20 1996-12-14 New 1-phenylalkyl / alkylene-4 - (. Alpha.-hydroxydiphenylmethyl) piperidine derivatives and their use as serotonin antagonists Ceased DE19681115D2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19681115T DE19681115D2 (en) 1995-12-20 1996-12-14 New 1-phenylalkyl / alkylene-4 - (. Alpha.-hydroxydiphenylmethyl) piperidine derivatives and their use as serotonin antagonists

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19547622 1995-12-20
PCT/EP1996/005626 WO1997022583A1 (en) 1995-12-20 1996-12-14 Novel 1-phenylalkyl/alkylene-4-(.alpha.-hydroxydiphenylmethyl)-piperidine derivatives and their use as serotonin antagonists
DE19681115T DE19681115D2 (en) 1995-12-20 1996-12-14 New 1-phenylalkyl / alkylene-4 - (. Alpha.-hydroxydiphenylmethyl) piperidine derivatives and their use as serotonin antagonists

Publications (1)

Publication Number Publication Date
DE19681115D2 true DE19681115D2 (en) 1999-11-25

Family

ID=7780683

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19681115T Ceased DE19681115D2 (en) 1995-12-20 1996-12-14 New 1-phenylalkyl / alkylene-4 - (. Alpha.-hydroxydiphenylmethyl) piperidine derivatives and their use as serotonin antagonists

Country Status (3)

Country Link
AU (1) AU1301497A (en)
DE (1) DE19681115D2 (en)
WO (1) WO1997022583A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USH1996H1 (en) * 1997-11-20 2001-10-02 Fmc Corporation Insecticidal photostable acid salt derivatives of N-benzyl-4-benzhydrolpiperidines
DE19939756A1 (en) * 1999-08-21 2001-02-22 Merck Patent Gmbh New 1-(1-ethyl-piperidin-4-yl)-1-(phenyl or heterocyclyl)-alkanol derivatives, are 5-HT(2A) receptor antagonists useful e.g. for treating schizophrenia, depression, memory disorders or eating disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3014037A (en) * 1957-09-12 1961-12-19 Searle & Co N-alkoxyphenalkyl-alpha, alpha-diphenyl-4-piperidinemethanols and processes
GB845822A (en) * 1958-09-15 1960-08-24 Searle & Co Improvements in or relating to piperidine derivatives
US3068237A (en) * 1961-03-17 1962-12-11 Searle & Co N-[(chloro/nitro/amino)phenylalkyl]-alpha, alpha-diphenylpipidinemethanols
GB1542823A (en) * 1977-01-11 1979-03-28 Ucb Sa Piperidine derivatives
CA1280421C (en) * 1985-07-02 1991-02-19 Albert A. Carr 1,4-disubstituted piperidinyl derivatives
DE3917241A1 (en) * 1989-05-26 1990-11-29 Schaper & Bruemmer Gmbh 4- (HYDROXYDIPHENYLMETHYL) -1-PIPERIDYL-PHENYLALKANE DERIVATIVES
US5569664A (en) * 1995-02-16 1996-10-29 Fmc Corporation Insecticidal n-(substituted arylmethyl)-4-[bis(substituted phenyl) methyl]pi

Also Published As

Publication number Publication date
WO1997022583A1 (en) 1997-06-26
AU1301497A (en) 1997-07-14

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Legal Events

Date Code Title Description
8131 Rejection