DE1943441A1 - Denture cleaner - Google Patents

Abstract

The prepn. contains alkaline reacting salts of alkali metal, enzymes and, optinally, peroxide cpds. A tenside (0.1-5%) and a soluble calcium and/or magnesium salt (0.1-2%) is also added. Preferably, the prepn. has pH 7-10.5.

Description

Denture Cleaners The present invention relates to a denture cleaning agent containing alkaline salts the alkali metals, enzymes and optionally peroxo compounds, which is characterized istg that there is an additional 0.1 to 5% surfactants and 0.1 to 2% soluble calcium and / or Contains magnesium salts.

The previous denture cleaners mainly exist from alkaline-reacting salts of alkali metals and can be an additive Peroxo compounds such as sodium perborate contain. However, you have the disadvantage that when inserting the dentures in the immobile liquor of the cleaning agent the plaque of the teeth is insufficiently removed. If the detergent is peroxo compounds contains, these cause a bleaching of the plaque; the toppings themselves however, they are not removed sufficiently and continue to form foci.

Pure dentifrices, especially toothpastes, were also used already several additions of enzymes, e.g. pepsin, papain or pancreatin, suggested. -Pepsin is only effective in a strongly acidic environment and therefore could not prove. Papain is also effective in a weakly alkaline environment; only the exposure time a 7ahnpasti is far too short to achieve an effect. Pancreatin was Suggested for toothpaste together with soap, but the soap inhibits noticeably the enzyme activity. In addition, enzymes in the presence of water are limited are durable. In addition, the noticeable odor of many enzyme preparations becomes more animal Origin, including pancreatin, found in toothpastes very unpleasant.

The German patent 734 765 describes a powder cleaning agent ftl for dentures, which is a tryptic, protein-dissolving enzyme and a dry Peroxide or peroxide derivative in addition to alkaline salts such as sodium carbonate, contains. However, the enzymatic effectiveness of such detergents could in practice only be very limited, since the large amounts of peroxo compounds used in the intended composition had to at least partially inactivate the enzymes.

The laid-open specification t 467 951 describes the use of proteolytic Enzymes such as preoteases, pancreatic trypsin, trypsin, paparin or mold protesis, Lipases and amy salts in tooth cleaning agents made from cleaning agents, binders, foaming agents, Humectants, aromatics, sweeteners and spices as well as active ingredients, their pH value should preferably be set to 6.7 to 6.8. So much for such dentifrices should also include denture cleansers, their enzymatic effectiveness can - especially at the specified pR value - but only to a very limited extent and by no means sufficient to remove the plaque from the dentures.

The cleaning agent according to the invention for dentures has for the first time a surprising enzymatic activity requiring complete removal the plaque is guaranteed by the dentures. This surprising enzymatic Effectiveness is based on the simultaneous presence of soluble Ca and / or Mg salts, which stabilize the enzymes, and the surfactants which are not effective increase in a predictable manner.

One has already been based in denture cleaners of alkaline salts and peroxo compounds surfactants are used. Man however, could not expect the surfactants to increase the activity of the enzymes were because previously surfactants had often adversely affected enzymes.

The surfactants used for the present invention are non-toxic and have a taste suitable, non-hydroscopic, synthetic surface-active substances, e.g. Salts of alkyl sulphates, salts of alkyl sulphoaoetates, salts of sulphated monoglycerides, Polypropylene glycol-ethylene oxide condensates, sucrose fatty acid residues and quaternaries Understood ammonium compounds. The proportion of surfactants in the cleaning agent is 0.1 to 5%, preferably 0.1 to 1%, of the soluble ones used according to the invention Ca and / or Mg salts surf not be hygroscopic. Your share in the detergent is 0.1 to 2%, preferably 0.3 to 2%.

Mixtures are used as enzymes in the cleaning agents according to the invention from proteases, amylase (or esterase) and lipases used in the basic Area-effective ..

Usable enzymes come from animal organs or from bacterial cultures. Enzymes from animal organs must be particularly pure so that they are often used adherent, unpleasant odor turned off wind. Enzyme mixtures from bacterial cultures, which contain proteases, amylases and lipases are under different names im trades examples of such. Mixtures of enzymes are detergentase and maxatase. The proportion of enzyme mixtures in the cleaning agent is approximately 0.1 to 5%, preferably 0.5 to 2%. The proteolytic activity should be at least 1000 D.E. / g detergent lie.

The pH of the cleaning agent according to the invention is 7 to 10.5. On this pH-fle-rich, -which-corresponds to the range of action of the enzymes, be the basic ingredients of the denture cleaner are discontinued. Basic ingredients are the alkaline reacting salts of the alkali metals such as trisodium phosphate, Sodium carbonate, sodium hydrogen carbonate and sodium tripolyphosphate. By adding Alkali phosphates in particular have their known cleaning effect at the same time exploited The addition of peroxo compounds can be advantageous, but is not necessary. Examples of useful peroxo compounds are sodium perborate and Sodium perpyrophosphate.

The proportion of peroxo compounds should not be too large to avoid any To cause inactivation of the enzymes.

The following examples illustrate the invention: Example 1 It was a powder mixed from the following ingredients: 24.5 T. sodium perborate 35, Q T. Sodium sesquicarbonate (Na2CO3 # NaHCO3) 20.0 T. Trisodium phosphate 19.0 T. Sodium pyrophosphate 0.5 T. Calcium gluconate 0.7 T. Detergenase (400,000 D.U./g) 0.2 T. Sodium Lauryl Sulphoacetate 0.1 T. Flavors and Aromas A common proportion the powder was dissolved in warm water. A denture was placed in this aqueous solution inserted. The denture was completely cleaned in about 30 minutes and the rinsed prosthesis was odorless.

Example 2 A powder was mixed from the following ingredients: 30.0 T. sodium perpyrophosphate 30.0 T. sodium sesquicarbonate 34.0 T. trisodium phosphate 0.5 T. calcium disodium ethylenediamine tetraacetate 2 0 T. detergentase 0.3 T. sodium lauryl sulfate 90% 3t1 T. sodium sulphate 0.1 T. Flavors and aromas.

First the detergentase was premixed with the sodium sulfate and the premix is then mixed with the remaining ingredients. The powder was compressed into tablets in the usual way. In an aqueous solution of a tablet a dental prosthesis was inserted, which was completely cleaned after 1.5 hours. The rinsed prosthesis was odorless Similar results were obtained obtained when instead of 30 parts of sodium sesquicarbonate, 30 parts of sodium carbonate were used.

Example 3 With a premix of sodium sulfate and detergentase, mixed with powder from the following ingredients: 5.0 T. sodium pyrophosphate 85.0 T. sodium sesquicarbonate 5.0 T. sodium sulfate 2.0 T. trisodium phosphate 2.0 T. detergentase 0.5 T. Magnesium gluconate 0.2 T. Surfactants (e.g. monolaurine sulfate) 0.1 T. Flavor and flavorings 0.2 T. antiseptics.

So this powder did not contain any peroxo compound.

In an aqueous solution of a common portion of the powder was a Dental prosthesis inserted which was constantly cleaned after 3 hours - the rinsed The prosthesis was odorless.

Similar results were obtained if instead of the 5 parts sodium pyrophosphate 5 parts of sodium perpyrophosphate were used

Claims (2)

Claims: 1. Denture cleaning agent with a content on alkaline salts of alkali metals, enzymes and possibly peroxo compounds, characterized in that it also contains 0.1 to 5% surfactants and 0.1 to 2.% soluble Contains calcium and / or magnesium salts. 2. Denture cleaning agent according to claim 1, characterized in that that it has a pH of 7 to 10.5.