DE10344169A1 - Konfokales Endomikroskop - Google Patents

Konfokales Endomikroskop Download PDF

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Publication number
DE10344169A1
DE10344169A1 DE10344169A DE10344169A DE10344169A1 DE 10344169 A1 DE10344169 A1 DE 10344169A1 DE 10344169 A DE10344169 A DE 10344169A DE 10344169 A DE10344169 A DE 10344169A DE 10344169 A1 DE10344169 A1 DE 10344169A1
Authority
DE
Germany
Prior art keywords
endomicroscope
optical
furthermore
microlens
proximal end
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE10344169A
Other languages
English (en)
Inventor
Ingo Krohne
Andre Erhardt
Klaus M Irion
Herbert Stepp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung eV
Karl Storz SE and Co KG
Original Assignee
Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung eV
Karl Storz SE and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung eV, Karl Storz SE and Co KG filed Critical Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung eV
Priority to DE10344169A priority Critical patent/DE10344169A1/de
Priority to PCT/DE2004/002035 priority patent/WO2005031435A1/de
Priority to US10/573,141 priority patent/US20070053204A1/en
Priority to EP04786756A priority patent/EP1664892A1/de
Publication of DE10344169A1 publication Critical patent/DE10344169A1/de
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0068—Confocal scanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0028—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders specially adapted for specific applications, e.g. for endoscopes, ophthalmoscopes, attachments to conventional microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
    • G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
    • G02B23/2407—Optical details
    • G02B23/2461—Illumination

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Astronomy & Astrophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microscoopes, Condenser (AREA)
  • Instruments For Viewing The Inside Of Hollow Bodies (AREA)
  • Endoscopes (AREA)

Abstract

Es wird ein konfokales Endomikroskop vorgestellt, bei dem der Durchmesser von Lichtleitfasern am proximalen Ende (8) eines Lichtleiterbündels (9) größer ist als am distalen Ende (15). Hierdurch wird die Effizienz der Einkopplung von Licht einer Lichtquelle erhöht, ohne hierdurch die Auflösung des Endomikroskops zu verringern. Des Weiteren wird vorgeschlagen, die Lichtleiter (10) an ihrem proximalen Ende (8) in einem Raster, zum Beispiel mittels einer die einzelnen Lichtleiter (10) aufnehmenden Faseraufnahme-Einheit (11) anzuordnen. Des Weiteren kann eine Mikrolinsen-Einheit (13) vorgesehen sein, durch die jedem Lichtleiterende eine Mikrolinse (14) zugeordnet ist.
DE10344169A 2003-09-22 2003-09-22 Konfokales Endomikroskop Ceased DE10344169A1 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DE10344169A DE10344169A1 (de) 2003-09-22 2003-09-22 Konfokales Endomikroskop
PCT/DE2004/002035 WO2005031435A1 (de) 2003-09-22 2004-09-10 Konfokales endomikroskop mit sich im durchmesser verjüngenden lichtleitfasern
US10/573,141 US20070053204A1 (en) 2003-09-22 2004-09-10 Confocal microendoscope comprising optical fibres with a tapering diameter
EP04786756A EP1664892A1 (de) 2003-09-22 2004-09-10 Konfokales endomikroskop mit sich im durchmesser verjüngenden lichtleitfasern

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10344169A DE10344169A1 (de) 2003-09-22 2003-09-22 Konfokales Endomikroskop

Publications (1)

Publication Number Publication Date
DE10344169A1 true DE10344169A1 (de) 2005-05-04

Family

ID=34384237

Family Applications (1)

Application Number Title Priority Date Filing Date
DE10344169A Ceased DE10344169A1 (de) 2003-09-22 2003-09-22 Konfokales Endomikroskop

Country Status (4)

Country Link
US (1) US20070053204A1 (de)
EP (1) EP1664892A1 (de)
DE (1) DE10344169A1 (de)
WO (1) WO2005031435A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011007878A1 (de) * 2011-04-21 2012-10-25 Karl Storz Gmbh & Co. Kg Lichtleitereinrichtung für ein Endoskop

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9068917B1 (en) * 2006-03-14 2015-06-30 Kla-Tencor Technologies Corp. Systems and methods for inspection of a specimen
CN100470295C (zh) * 2006-09-26 2009-03-18 河北工业大学 一种光学显微镜透射照明系统及使用它的光学显微镜
WO2008144831A1 (en) * 2007-05-30 2008-12-04 Invision Medical Technologies Pty Ltd Method and apparatus for inspecting tissue
DE102009025815A1 (de) * 2009-05-15 2010-11-25 Degudent Gmbh Messanordnung sowie Verfahren zum dreidimensionalen Messen eines Objektes
US9885859B2 (en) * 2012-07-05 2018-02-06 Martin Russell Harris Structured illumination microscopy apparatus and method
DE102013015932A1 (de) * 2013-09-19 2015-03-19 Carl Zeiss Microscopy Gmbh Hochauflösende Scanning-Mikroskopie
CN111624735B (zh) * 2020-05-13 2021-10-26 熊艳辉 浸液式高分辨率小口径光纤显微物镜

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4938205A (en) * 1988-05-27 1990-07-03 The University Of Connecticut Endoscope with traced raster and elemental photodetectors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3853658A (en) * 1971-07-12 1974-12-10 R Ney Fiber optical image magnifier panel and method of manufacture
US6464633B1 (en) * 1999-08-23 2002-10-15 Olympus Optical Co., Ltd. Light source device for endoscope using DMD
US7031579B2 (en) * 2002-06-26 2006-04-18 L-3 Communications Corporation High resolution display component, system and method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4938205A (en) * 1988-05-27 1990-07-03 The University Of Connecticut Endoscope with traced raster and elemental photodetectors

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
"Parallele optische Verbindungsnetzwerke mit zwei-dimensionalen Koppelelementen", 30.3.1999, Disser-tation Uwe Danzer, Lehrstuhl für Optik, Universi- tät Erlangen-Nürnberg *
Ergänzungsband 1, Teil 1, S. 206-208 *
Krohne, I.(u.a.): News Concept for the Develope- ment of a Confocal Endomicroscope. In: Biomedi- zinische Technik, 2002, Bd. 47 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011007878A1 (de) * 2011-04-21 2012-10-25 Karl Storz Gmbh & Co. Kg Lichtleitereinrichtung für ein Endoskop
US9964752B2 (en) 2011-04-21 2018-05-08 Karl Storz Se & Co. Kg Light-conducting device for an endoscope

Also Published As

Publication number Publication date
WO2005031435A1 (de) 2005-04-07
EP1664892A1 (de) 2006-06-07
US20070053204A1 (en) 2007-03-08

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8131 Rejection