DE10337710A1 - Solution for a parenteral intravenous application contains amiodaron, an aldonic acid or uronic acid or its glycosides or a carboxylic acid, and a suitable isotonic agent - Google Patents

Solution for a parenteral intravenous application contains amiodaron, an aldonic acid or uronic acid or its glycosides or a carboxylic acid, and a suitable isotonic agent Download PDF

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Publication number
DE10337710A1
DE10337710A1 DE10337710A DE10337710A DE10337710A1 DE 10337710 A1 DE10337710 A1 DE 10337710A1 DE 10337710 A DE10337710 A DE 10337710A DE 10337710 A DE10337710 A DE 10337710A DE 10337710 A1 DE10337710 A1 DE 10337710A1
Authority
DE
Germany
Prior art keywords
acid
glycosides
solution
amiodaron
isotonic agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE10337710A
Other languages
German (de)
Inventor
Klaus Sommermeyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Supramol Parenteral Colloids GmbH
Original Assignee
Supramol Parenteral Colloids GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Supramol Parenteral Colloids GmbH filed Critical Supramol Parenteral Colloids GmbH
Priority to DE10337710A priority Critical patent/DE10337710A1/en
Publication of DE10337710A1 publication Critical patent/DE10337710A1/en
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Solution contains 50-0.2 mg/ml amiodaron, a physiologically compatible aldonic acid or its glycosides, uronic acid or its glycosides, less than 1 molar polyhydroxydicarboxylic acid, monohydroxydicarboxylic acid, monohydroxytricarboxylic acid or their salts, and a suitable isotonic agent. The solution has a pH of 2.5-4.5.
DE10337710A 2003-08-16 2003-08-16 Solution for a parenteral intravenous application contains amiodaron, an aldonic acid or uronic acid or its glycosides or a carboxylic acid, and a suitable isotonic agent Withdrawn DE10337710A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE10337710A DE10337710A1 (en) 2003-08-16 2003-08-16 Solution for a parenteral intravenous application contains amiodaron, an aldonic acid or uronic acid or its glycosides or a carboxylic acid, and a suitable isotonic agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10337710A DE10337710A1 (en) 2003-08-16 2003-08-16 Solution for a parenteral intravenous application contains amiodaron, an aldonic acid or uronic acid or its glycosides or a carboxylic acid, and a suitable isotonic agent

Publications (1)

Publication Number Publication Date
DE10337710A1 true DE10337710A1 (en) 2005-03-10

Family

ID=34177643

Family Applications (1)

Application Number Title Priority Date Filing Date
DE10337710A Withdrawn DE10337710A1 (en) 2003-08-16 2003-08-16 Solution for a parenteral intravenous application contains amiodaron, an aldonic acid or uronic acid or its glycosides or a carboxylic acid, and a suitable isotonic agent

Country Status (1)

Country Link
DE (1) DE10337710A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2712611A1 (en) * 2012-09-27 2014-04-02 B. Braun Melsungen AG Stabilized aqueous compositions of neuromuscular blocking agents

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2712611A1 (en) * 2012-09-27 2014-04-02 B. Braun Melsungen AG Stabilized aqueous compositions of neuromuscular blocking agents
WO2014048836A1 (en) * 2012-09-27 2014-04-03 B. Braun Melsungen Ag Stabilized aqueous compositions of neuromuscular blocking agents
CN104519872A (en) * 2012-09-27 2015-04-15 B·布郎梅尔松根股份公司 Stabilized aqueous compositions of neuromuscular blocking agents
JP2015531359A (en) * 2012-09-27 2015-11-02 ビー．ブラウン メルズンゲン アーゲーＢ．Ｂｒａｕｎ Ｍｅｌｓｕｎｇｅｎ Ａｇ Stabilized aqueous composition of neuromuscular blocking agents
AU2013322897B2 (en) * 2012-09-27 2017-07-27 B. Braun Melsungen Ag Stabilized aqueous compositions of neuromuscular blocking agents
CN104519872B (en) * 2012-09-27 2017-12-01 B·布郎梅尔松根股份公司 The stable aqueous composition of neuromuscular blocking agents

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Date Code Title Description
8139 Disposal/non-payment of the annual fee