DE102017130737A1 - Method for the automated production of creams - Google Patents

Method for the automated production of creams

Info

Publication number
DE102017130737A1
DE102017130737A1 DE102017130737.0A DE102017130737A DE102017130737A1 DE 102017130737 A1 DE102017130737 A1 DE 102017130737A1 DE 102017130737 A DE102017130737 A DE 102017130737A DE 102017130737 A1 DE102017130737 A1 DE 102017130737A1
Authority
DE
Germany
Prior art keywords
individual
container
pharmaceutical
preparation
process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE102017130737.0A
Other languages
German (de)
Inventor
Bernward Starke
Bernhard Mueller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Delphi Salesconsulting AG
Mworks GmbH
Original Assignee
Delphi Salesconsulting AG
Mworks GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delphi Salesconsulting AG, Mworks GmbH filed Critical Delphi Salesconsulting AG
Priority to DE102017130737.0A priority Critical patent/DE102017130737A1/en
Publication of DE102017130737A1 publication Critical patent/DE102017130737A1/en
Application status is Pending legal-status Critical

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F13/00Other mixers; Mixing plant, including combinations of mixers, e.g. of dissimilar mixers
    • B01F13/10Mixing plant, including combinations of mixers, e.g. of dissimilar mixers
    • B01F13/1072Plants with a plurality of mixing receptacles or mixing tools, e.g. the receptacles or tools being able to be indexed into different working positions along a line or along a circle
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F13/00Other mixers; Mixing plant, including combinations of mixers, e.g. of dissimilar mixers
    • B01F13/10Mixing plant, including combinations of mixers, e.g. of dissimilar mixers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F15/00Accessories for mixers ; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F15/04Forming a predetermined ratio of the substances to be mixed
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F15/00Accessories for mixers ; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F15/04Forming a predetermined ratio of the substances to be mixed
    • B01F15/0441Forming a predetermined ratio of the substances to be mixed by feeding the components in predetermined amounts
    • B01F15/0445Forming a predetermined ratio of the substances to be mixed by feeding the components in predetermined amounts by weighing, e.g. with automatic discharge
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003Filling medical containers such as ampoules, vials, syringes or the like
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/26Methods or devices for controlling the quantity of the material fed or filled
    • GPHYSICS
    • G06COMPUTING; CALCULATING; COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F1/00Details not covered by groups G06F3/00 – G06F13/00 and G06F21/00
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F2215/00Auxiliary or complementary information in relation with mixing
    • B01F2215/0001Field of application of the mixing device
    • B01F2215/0031Mixing ingredients for cosmetic, perfume compositions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F2215/00Auxiliary or complementary information in relation with mixing
    • B01F2215/0001Field of application of the mixing device
    • B01F2215/0032Mixing ingredients for pharmaceutical, homeopathical compositions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B2220/00Specific aspects of the packaging operation
    • B65B2220/14Adding more than one type of material or article to the same package

Abstract

The invention relates to a process for the preparation of individualized mixtures for a pharmaceutical and / or cosmetics. It includes the steps of reading an individual recipe for the production of a final product, assignment of the individual recipe or the type and amount of a plurality of individual components to a container, positioning the container and a metering device for a designated in the individual formulation individual component to each other and filling the container with one of Individual components named in the individual recipe. The individual formulation names at least the type and mass or volume of a plurality of individual components.

Description

  • The invention relates to a device for automated change of the composition of a batch, and a corresponding method.
  • Every skin type has its own individual characteristics. For optimal care, care products that are adapted to the individual skin type are therefore necessary. However, the production of individualized care products has so far only been possible in a very cost-intensive manner, since automated production has hitherto not been possible and every product has to be mixed by hand. As a result, individualized care products are only available at very high prices and are therefore not accessible to the masses. The same applies to the production of individualized medicines, so-called extemporaneous preparations.
  • It is therefore an object of the present invention to provide a method which enables an individualized production of medicaments or care products tailored to an individual requirement of the patient or customer in a fully automatic production.
  • The object of the invention is achieved by a method according to independent claim 1.
  • The process according to the invention for the production of individualized mixtures for a pharmaceutical and / or cosmetics has four process steps. First, an individual recipe for the production of a final product is read. The individual formulation names at least the type and quantity of a plurality of individual components, the unit of the quantity is usually given in mass or volume. Thereafter, the individual formulation or type and amount of a plurality of individual components is associated with a container that receives the final product. In the third method step, the container and a dosing device are positioned relative to one another such that an individual component named in the individual formulation can be filled into the container by means of the dosing device. In the fourth method step, an individual component named in the individual formulation is filled into the container by means of the metering device. Advantageously, method steps three and four are repeated for the subsequent individualized mixture.
  • Due to this method, it is possible to manufacture in particular individualized formulations. The individual recipes are combined in the container and stored. Sequence, proportion and number of different components can be adjusted within wide limits depending on the type of product. Different products can be realized by the method according to the invention, e.g. Mixture of a liquid, paste or powder of different active ingredients, e.g. Creams or oils. Also possible is the packaging of a set of different items, e.g. Tablets for a big pharmacy in the hospital.
  • Further embodiments of the invention for the method are set forth in the subclaims 2 to 14.
  • In a further embodiment of the invention, the type and quantity of basic components are read in as the individual formulation is read. For example, a cream typically contains a plurality of basic components that are the same for each cream, e.g. Glycerol. The active ingredients of the cream vary depending on the purpose.
  • In a further embodiment of the invention, the type and amount of the base components of the cream are selected such that the cream prepared according to the individual formulation has a viscosity in a predetermined range of 10 to 250,000 mPas, preferably 100 to 100,000 mPas and particularly preferably 1,000 to 25,000 mPas. Due to this viscosity of the cream, thorough mixing of the individual components and the base components during a standardized mixing process after filling the container is ensured.
  • In a further embodiment according to the invention, the order of addition of the individual components is determined from the individual formulation. To avoid the formation of inhomogeneities or reactions of the individual components with each other, in some cases a certain order of addition of the individual components must be taken into account. If this is not the case, reduced stability of the mixtures, reactions of individual components and consequently undesired reaction products and / or precipitation of individual components may occur. Furthermore, the temperatures at which certain individual components must be added may be different and thus make a certain order production-wise or make economic sense.
  • Stability is an important quality feature for medicines and creams. This applies to the same extent for medicines individually prepared in the formulation for internal or external purposes or creams. A drug is considered to be stable if its important properties do not change for a reasonable amount of time or only to an acceptable extent. The Stability should therefore be fulfilled for at least 1 week, preferably 1 month and more preferably 6 months. In creams, the time requirements are much longer and are developed, tested and determined during product development. In terms of stability or instability, a distinction is made between chemical, physical, microbiological and photo instability.
  • In a further embodiment of the invention, the container is filled with basic components. Depending on the embodiment of the method according to the invention, the container can be filled with individual components with the basic components before, during or after filling of the container.
  • In a further embodiment of the invention, the filling of the containers with base components takes place in a different production area than the filling of the containers with individual components. Because the type and amount of the base components are substantially the same for each cream prepared according to the individual formulation, the containers can be filled with basic components by known filling methods, e.g. also by external suppliers. The filling of the containers with individual components takes place by means of the method according to the invention. By this design of the method according to the invention, the production of an individualized mixture is simplified and thus more cost-effective.
  • In a further embodiment of the invention, a control command is generated in a control unit. The control command is formed from the quantity of an individual component read in the individual recipe. The control command thus also contains the type and quantity of the individual components of a read-in individual recipe of a mixture that has been read into the control unit.
  • In a further aspect of the invention, the control command is suitable for controlling a dosing device. About the metering a named in the individual recipe Individual component is filled in the container.
  • In a further embodiment of the invention, the control command includes a command for positioning the metering device. The control command positions the metering device on the container, which is to be filled with the corresponding individual component.
  • In a further embodiment of the invention, the control command contains a command for dispensing the previously read into the control unit amount of the individual component of the metering device. The container is filled via the metering device with the amount of the individual component of the mixture.
  • In a further embodiment of the invention, the control command generated in a control unit includes a command for positioning the container into which the mixture is filled. The container is positioned to exactly the metering device with which the container is to be filled with the individual component of the mixture.
  • In a further embodiment of the invention, the metering device is controlled so that the metering device emits the read amount of the individual component in the container. This design ensures that exactly the container is filled with the correct type and amount of the individual component of the mixture, which was previously read into the control unit.
  • In a further embodiment of the invention, the components which have been filled into the container via the metering device are mixed together. The mixture contains basic components which have been filled into the container in another production area and individual components which have been filled into the container by the method according to the invention. All components are filled after filling with all components or after filling with an individual component via e.g. mixed a mixer into a homogeneous mixture.
  • In an advantageous embodiment of the invention, the production area for filling the containers with individual components has a plurality of product lines, which are arranged parallel to one another. On these product lines, a plurality of containers are positioned to the metering devices. Due to this advantageous embodiment, the filling of the containers per unit time is significantly increased, the production costs are low for each individualized mixture produced. The substantially equal product lines allow a high degree of serviceability of the production area, the risk of a total failure in a defective product line is low. Due to the modular design of the production area can be easily extended according to the number of containers to be filled.
  • In a further embodiment of the invention, a plurality of metering devices for filling the containers with individual components is positioned parallel to a plurality of the product lines. Along each product section, due to this arrangement of the metering devices, each container can be filled with a plurality of individual components via the metering devices. This embodiment of the invention increases the production of individualized mixtures per unit time and thus reduces the production costs. Number and type of metering devices can also be easily and inexpensively changed depending on the purpose of the mixture.
  • In a further embodiment of the invention, a plurality of containers along a plurality of parallel product lines to a plurality of metering devices is positioned. Due to this advantageous embodiment, the filling of the containers per unit time is significantly increased, the production costs are low for each individualized mixture produced. The ease of maintenance, redundancy of the components of the production area and thus its resilience is high. Due to the modular design of the production area can be easily extended according to the number of containers to be filled.
  • In a further embodiment of the invention, the method according to the invention comprises the creation of a first data packet. This first data packet contains data for the notification of the end product and serves to identify a mixture to be filled into a container. The first data packet is used to compare the quantity and composition of a ordered mixture with an already prepared mixture. This ensures accurate monitoring of the production process at all times.
  • In a further embodiment of the invention, the first data packet is output. The output of the first data packet serves the control unit to identify a mixture to be filled into a container and already filled. This ensures constant monitoring and quality assurance of production.
  • In a further embodiment of the invention, the output of the first data packet takes place electronically. The first data packet is e.g. stored on an RFID chip, which is connected to the container by means of suitable devices for orientation and support in the transport systems of the production area. The output of the first data packet can also be done on a screen to allow an operator to monitor and document the production process at any time.
  • In a further embodiment of the invention, a second data packet is created. This second data packet contains data for the labeling of the final product and data on the composition of the mixture, product name and other data that are important for the end user.
  • In a further embodiment of the invention, the second data packet is output. By issuing the data of the second data packet to the end user e.g. made accessible via an app and / or in print.
  • In a further embodiment of the invention, the output of the second data packet takes place on a printer. The printed form of the second data packet is affixed to the container, usually glued, e.g. as a QR code. The customer has the option to order the identical formula at a later date via a smartphone app by scanning the QR code on the bottom of a container.
  • In a further inventive embodiment of the invention, the process steps for the production of a second mixture are repeated. This includes at least the method steps reading an individual recipe for the production of the second mixture, assignment of the individual formulation or the type and quantity of a plurality of individual components to a container, positioning the container and a dosing device for an individual component named in the individual formulation each other and filling the container with one of the individual components named in the individual recipe. In a development according to the invention, the individual formulation of the first mixture is different from the individual formulation of the second mixture. In a further advantageous embodiment of the invention, the change from the production of the first mixture for the production of the second mixture is fully automated. The change in production from a first individual recipe to another second individual recipe is carried out without further intervention in the production process from the outside, for example by entering a command.
  • Embodiments of the sensor device according to the invention and the method according to the invention are shown schematically simplified in the drawings and are explained in more detail in the following description.
  • Show it:
    • 1 Flowchart of the method according to the invention for the production of individualized mixtures
    • 2 Flowchart of the method according to the invention for the production of individualized mixtures with control commands and mixing of the components
    • 3 Flowchart of the method according to the invention for the production of individualized mixtures
    • 4 Communication paths and directions of the invention
    • Process for the preparation of individualized mixtures 5 View of a production area for the preparation of creams
    • 6 View of a container for receiving a pharmaceutical or a cosmetic
  • The inventive method 1 for the production of individualized mixtures 2 for a pharmaceutical and / or cosmetics has four process steps ( 1 ). First, the recipe for the production of the final product is read in 100. The individual formulation specifies at least the type and amount of a plurality of individual components, the unit of the amount is usually given in mass or volume. Thereafter, the individual recipe or type and amount of a plurality of individual components a container 4 associated 200 that absorbs the final product. In the third process step 300 become container 4 and a metering device 6 positioned to each other so that by means of the metering device 6 an individual component named in the individual formula the container 4 can be filled. In the fourth process step 400 is by means of the metering device 6 an individual component named in the individual formula in the container 4 filled. The method steps three 300 and four 400 are for the individualized mixture 2 repeated until all individual components of the recipe in the container 4 are filled, the procedure 1 so finished.
  • Because of this procedure 1 It is possible to manufacture in particular individualized recipes. The individual recipes are in the container 4 merged and stored. Sequence, proportion and number of different components can be adjusted within wide limits depending on the type of product. Different products can by the method according to the invention 1 be realized, for example, mixture of a liquid, paste or powder of different active ingredients such as creams or oils. Also possible is the packaging of a set of different items such as tablets for a large pharmacy in the hospital.
  • For example, a cream typically contains a plurality of basic components that are the same for each cream, eg, glycerine. These basic components account for the largest amount of a cream in terms of quantity and essentially determine their viscosity. The basic components are in the process according to the invention 1 chosen so that the viscosity of the cream as the end product is in the range of 1000 to 25000 mPas. However, the active ingredients of a cream vary depending on the purpose. Therefore, during the first process step, the type and quantity of the basic components are read in as well. The basic components themselves are usually before the individual components in the container 4 filled, as well as the basic components can be filled after filling with the individual components in the container.
  • 2 shows the schematic sequence of the method according to the invention 1 using control commands. In the first process step 100 the individual recipe for the production of the final product is read. In the second process step 200 the individual recipe becomes a container 4 assigned. In the third process step is in the control unit 8th a control command for positioning the container 250 generated. In the fourth process step 300 becomes the container 4 positioned so that by means of a metering device 6 the individual components in the container 4 can be filled. In the fifth process step 350 is in the control unit 8th generates a control command for dispensing a specific amount specified in the individual recipe. In the sixth process step 360 becomes the metering device 6 driven. In the seventh process step 400 is by means of the metering device 6 the individual component in the container 4 filled. To several different individual components in the same container 4 to fill, the steps three to seven are repeated until all specified in the individual formulation individual components in the container 4 are filled. In the eighth process step 500 be in the filled container 4 the components are mixed eg a mixer.
  • In 3 is the sequence of the method according to the invention 1 presented using data packets. In the first process step 100 the recipe for the production of the final product is read in. In the second process step 200 the individual recipe becomes a container 4 assigned. In the third process step 300 becomes the container 4 positioned so that by means of a metering device 6 the individual component in the container 4 can be filled. In the fourth process step 400 is by means of the metering device 6 an individual component named in the individual formula in the container 4 filled.
  • The method steps three 300 and four 400 are for the individualized mixture 2 repeated until all individual components of the recipe in the container 4 are filled. In the fifth process step 600 a first data packet is generated containing data for the notification of the final product. The first data package contains the recipe, container type identification and customer data and is stored permanently in a database together with the production data and the recipe. In the sixth process step 700 becomes the first Data packet output and stored eg on an RFID chip with the container 4 is connected by suitable devices for orientation and support in the transport systems of the production area. The first data packet is queried by an RFID scanner. In the seventh process step 800 a second data packet is generated, the data for the labeling of the final product and data about the composition of the mixture 2 , Product name and customer information. In the eighth process step 900 the second data packet is output and, for example, as a QR code on the container 4 appropriate. The customer has the option of using eg a smartphone app by scanning the QR code on the bottom of the container 4 to order the identical formula at a later date.
  • 4 shows the communication paths and directions of the method according to the invention 1 , In the for the procedure 1 central control unit 8th becomes the recipe for the individualized mixture 2 read in 100. The control unit 8th generates a control command 250 to the product line 3 to the container 4 along the product line 3 to the metering device 6 to be positioned so that by means of the metering device 6 the individual component in the container 4 can be filled. Is the positioning of the container 4 takes place, sends the product line 3 a corresponding signal to the control unit 8th , The control unit 8th generates a control command 350 to the metering device 6 attached to the container 4 is positioned and by a second control command of the control unit 8th the container 4 filled with the individual component. When this is done send the dosing device 6 a corresponding signal to the control unit 8th ,
  • The process of positioning the container 4 , Positioning of the dosing device 6 and filling the container 4 is repeated until all the individual components of the control unit 8th read recipe in the container 4 are filled. The control unit 8th sends control commands 250 . 350 on product lines 3 and dosing devices 6 and receives feedback on the execution. The control unit 8th also sends data packets 600 . 800 to the output unit 9 , The output unit 9 stores and outputs data on recipe, container identification and customer data. The output takes place, for example, on an RFID chip that is connected to the container 4 connected as well as a QR code on the container 4 ,
  • 5 shows a production area for the preparation of creams. The inventive method 1 starts by removing the containers 4 in the adapter loading station 19 in each case an adapter 18 be put. Depending on the container type, the appropriate adapter type is selected. The adapter 18 has a unique adapter ID that can be read by the RFID chip attached to it. The recipe ID, container type ID and adapter ID are linked to the data for the duration of production. The containers 4 be through the feed line 15 the production area and over buffer lines 16 fed in front of the product axes. The buffer line 16 stores some adapters 18 to waiting times of product axes or jams in the feed line 15 to avoid. A plurality of component lines 5 is essentially perpendicular to the product lines 3 arranged. Each dosing device 6 is in a node 7 a component section 5 with a product line 3 arranged or positionable. The nodes 7 are arranged in the form of an nxm matrix. About smugglers 17 become the containers 4 from the feed line 15 introduced into the product axes. The product axes position the containers 4 according to the recipe under the dosing axes. The dosing axes position the dosing devices 6 over the containers 4 and dose the programmed amount of the individual components into the containers 4 until all components are filled according to the recipe. After that, the containers are 4 from the product axes to the discharge line 22 introduced. At the end of the procedure 1 become the containers 4 in the adapter unloading station 20 from the adapters 18 taken. The empty adapters 18 become the adapter loading station 19 fed again.
  • A container 4 to accommodate the basic and individual components is in 6 shown. In the container 4 the cream is mixed and delivered to the end customer. Size and shape of the containers 4 can essentially be chosen freely. Are conceivable, for example, bottle, bottle and pump dispenser, etc. The container 4 has an anti-rotation 24 , eg a groove on, in the adapter 18 to stand against rotation. Every container 4 gets a unique label on the bottom. In this embodiment, it is a QR code 23 imprinted and is so clearly identifiable. The QR code 23 Contains the recipe ID, container type ID and / or set ID. This QR code 23 is stored in a database along with the manufacturing data and the composition of the batch 2 permanently saved. This ensures a clear manufacturing control and consistent quality assurance. Repeat orders can be conveniently triggered by the customer through, for example, a smartphone app.
  • LIST OF REFERENCE NUMBERS
  • 1
    method
    2
    mixture
    3
    product range
    4
    Container for transporting mixtures
    5
    components route
    6
    metering
    7
    junction
    8th
    control unit
    9
    output unit
    15
    feed section
    16
    buffer zone
    17
    Einschleuser
    18
    adapter
    19
    Adapterbeladestation
    20
    Adapterentladestation
    21
    Adapter feedback system
    22
    feed track
    50
    100
    Reading the recipe
    200
    Assignment of the recipe to a container
    250
    Generating a control command for positioning the container
    300
    Position the container
    350
    Generating a control command for dispensing a certain amount of an individual component
    360
    Controlling the metering device
    400
    Filling the container with an individual component
    500
    Mix the mixture
    600
    Create a first data packet
    700
    Output of the first data packet
    800
    Create a second data packet
    900
    Output of the second data packet

Claims (14)

  1. Method (1) for the production of individualized mixtures (2) for a pharmaceutical and / or cosmetics comprising the following method steps: a) reading in (100) an individual recipe for the preparation of a first mixture (2) wherein the individual formulation names at least the type and quantity of a plurality of individual components, where the quantity is given as mass or volume, b) Assignment (200) of the individual formula or the type and quantity of a plurality of individual components to a container (4) c) positioning (300) of the container (4) and a metering device (6) for an individual component named in the individual formulation to one another d) filling (400) of the container (4) with one of the individual components specified in the individual formulation wherein the method steps c) and d) are repeated for the further individual components mentioned in the individual formulation.
  2. Process (1) for the preparation of individualized mixtures (2) for a pharmaceutical and / or cosmetics according to Claim 1 characterized in that the type and amount of the individual components are chosen so that the cream prepared according to the individual formulation has a viscosity which is within a predetermined range, and / or has a stability longer than 1 week, preferably longer than 1 month and especially preferably lasts longer than 6 months.
  3. Process (1) for the preparation of individualized mixtures (2) for a pharmaceutical and / or cosmetics according to Claim 1 or 2 characterized in that the order of addition of the individual components is determined from the individual formulation.
  4. Process (1) for the preparation of individualized mixtures (2) for a pharmaceutical and / or cosmetics according to one or more of Claims 1 to 3 characterized in that the container (4) is filled with base components, wherein the filling (50) of the containers (4) with the base components in a different production area than the filling (400) of the containers (4) with the individual components.
  5. Process (1) for the preparation of individualized mixtures (2) for a pharmaceutical and / or cosmetics according to one or more of Claims 1 to 4 characterized in that the method (1) comprises generating (350, 360) a control command in a control unit (8), wherein the control command is generated from the read from the individual recipe amount of an individual component.
  6. Process (1) for the preparation of individualized mixtures (2) for a pharmaceutical and / or cosmetics according to Claim 5 characterized in that the control command includes a command for positioning the metering device (6).
  7. Process (1) for the preparation of individualized mixtures (2) for a pharmaceutical and / or cosmetics according to Claim 5 or 6 characterized in that the control command is a command for dispensing the read amount of the metering device (6).
  8. Process (1) for the preparation of individualized mixtures (2) for a pharmaceutical and / or cosmetics according to one or more of Claims 5 to 7 characterized in that the method (1) comprises the control (350, 360) of the metering device (6), wherein the control takes place such that from the metering device (6) the read amount is delivered.
  9. Process (1) for the preparation of individualized mixtures (2) for a pharmaceutical and / or cosmetics according to one or more of Claims 1 to 8th characterized in that a plurality of containers (4) along parallel product lines (3) to a plurality of metering devices (6) are positioned.
  10. Process (1) for the preparation of individualized mixtures (2) for a pharmaceutical and / or cosmetics according to one or more of Claims 1 to 9 characterized in that the method comprises creating (600) a first data packet, the data packet including data for the notification of the final product, the method comprising outputting (700) the first data packet, the output being electronic.
  11. Process for the preparation of individualized mixtures for a pharmaceutical and / or cosmetics according to one or more of Claims 1 to 10 characterized in that the method comprises creating (800) a second data packet, the data packet including data for labeling the end product, the method comprising outputting (900) the second data packet, wherein the output (900) of the second data packet is a printer.
  12. Process (1) for the preparation of individualized mixtures (2) for a pharmaceutical and / or cosmetics according to one or more of Claims 1 to 11 characterized in that the steps a) to d) for the production of a second mixture (2) repeat.
  13. Process (1) for the preparation of individualized mixtures (2) for a pharmaceutical and / or cosmetics according to Claim 12 characterized in that the individual formulation of the first mixture (2) are different from the individual formulation of the second mixture (2).
  14. Process (1) for the preparation of individualized mixtures (2) for a pharmaceutical and / or cosmetics according to Claim 12 or 13 characterized in that the change from the production of the first mixture (2) for the production of the second mixture (2) takes place fully automatically.
DE102017130737.0A 2017-12-20 2017-12-20 Method for the automated production of creams Pending DE102017130737A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE102017130737.0A DE102017130737A1 (en) 2017-12-20 2017-12-20 Method for the automated production of creams

Applications Claiming Priority (2)

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DE102017130737.0A DE102017130737A1 (en) 2017-12-20 2017-12-20 Method for the automated production of creams
PCT/EP2018/085911 WO2019121962A1 (en) 2017-12-20 2018-12-19 Method for the automated production of creams

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WO2001075586A1 (en) * 2000-03-31 2001-10-11 Imx Labs, Inc. Nail polish color selection system and method
US20020056724A1 (en) * 2000-08-25 2002-05-16 Manzari Kenneth Paul Apparatus suitable for preparing a custom personal care composition
DE102004020510A1 (en) * 2004-04-26 2005-11-10 Klingel, Hans, Dr.-Ing. e.h. Plant for the assembly of packing units with the proper prescription week needs of patients corresponding medicaments

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EP3085437B1 (en) * 2015-04-20 2018-09-19 INKMAKER S.r.l. System and method for delivery of fluids, in particular coloured fluids

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US5903465A (en) * 1993-08-23 1999-05-11 Elizabeth Arden Company Method and apparatus for customizing cosmetic products
WO2001075586A1 (en) * 2000-03-31 2001-10-11 Imx Labs, Inc. Nail polish color selection system and method
US20020056724A1 (en) * 2000-08-25 2002-05-16 Manzari Kenneth Paul Apparatus suitable for preparing a custom personal care composition
DE102004020510A1 (en) * 2004-04-26 2005-11-10 Klingel, Hans, Dr.-Ing. e.h. Plant for the assembly of packing units with the proper prescription week needs of patients corresponding medicaments

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