DE102011016191A1 - Verfahren zur Lokalisation von Primärtumoren aus Metastase-Gewebeproben und Applikationskits zu dessen Durchführung - Google Patents

Verfahren zur Lokalisation von Primärtumoren aus Metastase-Gewebeproben und Applikationskits zu dessen Durchführung Download PDF

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DE102011016191A1
DE102011016191A1 DE102011016191A DE102011016191A DE102011016191A1 DE 102011016191 A1 DE102011016191 A1 DE 102011016191A1 DE 102011016191 A DE102011016191 A DE 102011016191A DE 102011016191 A DE102011016191 A DE 102011016191A DE 102011016191 A1 DE102011016191 A1 DE 102011016191A1
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genes
tissue
ppwd1
tumor
abhd14b
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Nicole Posorski
Prof. Dr. Eggeling Ferdinand von
Dr. Hommann Merten
Dr. Kämmerer Daniel
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Universitaetsklinikum Jena
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Universitaetsklinikum Jena
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
DE102011016191A 2011-04-04 2011-04-04 Verfahren zur Lokalisation von Primärtumoren aus Metastase-Gewebeproben und Applikationskits zu dessen Durchführung Withdrawn DE102011016191A1 (de)

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DE102011016191A DE102011016191A1 (de) 2011-04-04 2011-04-04 Verfahren zur Lokalisation von Primärtumoren aus Metastase-Gewebeproben und Applikationskits zu dessen Durchführung

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DE102011016191A DE102011016191A1 (de) 2011-04-04 2011-04-04 Verfahren zur Lokalisation von Primärtumoren aus Metastase-Gewebeproben und Applikationskits zu dessen Durchführung

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009038754A2 (en) * 2007-09-19 2009-03-26 The Research Foundation Of State University Of New York Gene expression signatures in enriched tumor cell samples

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009038754A2 (en) * 2007-09-19 2009-03-26 The Research Foundation Of State University Of New York Gene expression signatures in enriched tumor cell samples

Non-Patent Citations (29)

* Cited by examiner, † Cited by third party
Title
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Capurso, G., Lattimore, S., Crnogorac-Jurcevic, T., Panzuto, F., Milione, M., Bhakta, V., Campanini, N., Swift, S., Bordi, C., Delle Fave, G. and Lemoine, N.: Gene expression profiles of progressive pancreatic endocrine tumours and their liver metastases reveal potential novel markers and therapeutic targets, Endocr Relat Cancer 13, 2006, 541-58
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Dennis, J., Hvidsten, T., Wit, E., Komorowski, J., Bell, A., Downie, I., Mooney, J., Verbeke, C., Bellamy, C., Keith, W. and Oien, K.: Markers of adenocarcinoma characteristic of the site of origin: development of a diagnostic algorithm, Clin Cancer Res 11, 2005, 3766-72
Dennis, J., Vass, J., Wit, E., Keith, W. and Oien, K.: Identification from public data of molecular markers of adenocarcinoma characteristic of the site of origin, Cancer Res 62, 2002, 5999-6005
Duerr, E., Mizukami, Y., Ng, A., Xavier, R., Kikuchi, H., Deshpande, V., Warshaw, A., Glickman, J., Kulke, M. and Chung, D.: Defining molecular classifications and targets in gastroenteropancreatic neuroendocrine tmors through DNA microarray analysis. Endocr Relat Cancer 15, 2008, 243-56
Dumur, C., Lyons-Weiler, M., Sciulli, C., Garrett, C., Schrijver, I., Holley, T., Rodriguez-Paris, J., Pollack, J., Zehnder, J., Price, M., Hagenkord, J., Rigl, C., Buturovic, L., Anderson, G. and Monzon, F.: Interlaboratory performance of a microarray-based gene expression test to determine tissue of origin in poorly differentiated and undifferentiated cancers, J Mol Diagn 10, 2008, 67-77
Giordano, T., Shedden, K., Schwartz, D., Kuick, R., Taylor, J., Lee, N., Misek, D., Greenson, J., Kardia, S., Beer, D., Rennert, G., Cho, K., Gruber, S., Fearon, E. and Hanash, S.: Organ-specific molecular classification of primary lung, colon, and ovarian adenocarcinomas using gene expression profiles, Am J Pathol 159, 2001, 1231-8
Horlings, H., van Laar, R., Kerst, J., Helgason, H., Wesseling, J., van der Hoeven, J., Warmoes, M., Floore, A., Witeveen, A., Lahti-Domenici, J., Glas, A., Van't Veer, L. and de Jong, D.: Gene expression profiling to identify the histogenetic origin of metastatic adenocarcinomas of unknown primary, J Clin Oncol 26, 2008, 4435-41
Horlings, H., van Laar, R., Kerst, J., Helgason, H., Wesseling, J., van der Hoeven, J., Warmoes, M., Floore, A., Witteveen, A., Lahti-Domenici, J., Glas, A., Van't Veer, L. and de Jong, D.: Gene expression profiling to identify the histogenetic origin of metastatic adenocarcinomas of unknown primary, J Clin Oncol 26, 2008, 4435-41
Khan, J., Wei, J., Ringnér, M., Saal, L., Ladanyi, M., Westermann, F., Berthold, F., Schwab, M., Antonescu, C., Peterson, C. and Meltzer, P.: Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks, Nat Med 7, 2001, 673-9
Lubensky, I. and Zhuang, Z.: Molecular genetic events in gastrointestinal and pancreatic neuroendocrine tmors, Endocr Pathol 18, 2007, 156-62
Ma, X., Patel, R., Wang, X., Salunga, R., Murage, J., Desai, R., Tuggle, J., Wang, W., Chu, S., Stecker, K., Raja, R., Robin, H., Moore, M., Baunoch, D., Sgroi, D. and Erlander, M. Molecular classification of human cancers using a 92-gene real-time quantitative polymerase chain reaction assay, Arch Pathol Lab Med 130, 2006, 465-73
Melle, C., Ernst, G., Schimmel, B., Bleul, A. and von Eggeling, F.: Colonderived liver metastasis, colorectal carcinoma, and hepatocellular carcinoma can be discriminated by the Ca(2+)-binding proteins S100A6 and S100A11, 2008, PLoS One 3, e3767
Moll, R.: The initial CUP situation and CUP syndrome: pathological diagnostics, Pathologe 30 Suppl 2, 2009, 161-7
Monzon, F., Lyons-Weiler, M., Buturovic, L., Rigl, C., Henner, W., Sciulli, C., Dumur, C., Medeiros, F. and Anderson, G.: Multicenter validation of a 1,550-gene expression profile for identification of tumor tissue of origin, J Clin Oncol 27, 2009, 2503-8
Park, S., Kim, B., Kim, J., Lee, S. and Kang, G.: Panels of immunohistochemical markers help determine primary sites of metastatic adenocarcinoma, Arch Pathol Lab Med 131, 2007, 1561-7
Ramaswamy, S., Tamayo, P., Rifkin, R., Mukherjee, S., Yeang, C., Angelo, M., Ladd, C., Reich, M., Latulippe, E., Mesirov, J., Poggio, T., Gerald, W., Loda, M., Lander, E. and Golub, T.: Multiclass cancer diagnosis using tumor gene expression signatures, Proc Natl Acad Sci USA 98, 2001, 15149-54
Shedden, K., Taylor, J., Enkemann, S., Tsao, M., Yeatman, T., Gerald, W., Eschrich, S., Jurisica, I., Giordano, T., Misek, D., Chang, A., Zhu, C., Strumpf D., Hanash, S., Shepherd, F., Ding, K., Seymour, L., Naoki, K., Pennell, N., Weir, B., Verhaak, R., Ladd-Acosta, C., Golub, T., Gruidl, M., Sharma, A., Szoke, J., Zakowski, M., Rusch, V., Kris, M., Viale, A., Motoi, N., Travis, W., Conley, B., Seshan, V., Meyerson, M., Kuick, R., Dobbin, K., Lively, T., Jacobson, J., Beer, D. and Adenocarcinoma, D. s. C. C. f. t. M. C. o. L.: Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study, Nat Med 14, 2008, 822-7
Su, A., Welsh, J., Sapinoso, L., Kern, S., Lapp, H., Dimitrov, P., Schultz, P., Powell, S., Moskaluk, C., Frierson, H. J. and Hampton, G.: Molecular classification of human carcinomas by use of gene expression signatures, Cancer Res 61, 2001, 7388-93
Talantov, D., Baden, J., Jatkoe, T., Hahn, K., Yu, J., Rajpurohit, Y., Jiang, Y., Choi, C., Ross, J., Atkins, D., Wang, Y. and Mazumder, A.: A quantitative reverse transcriptasepolymerase chain reaction assay to identify metastatic carcinoma tissue of origin, J Mol Diagn 8, 2006, 320-9
Tothill, R., Kowalczyk, A., Rischin, D., Bousioutas, A., Haviv, I., van Laar, R., Waring, P., Zalcberg, J., Ward, R., Biankin, A., Sutherland, R., Henshall, S., Fong, K., Pollack, J., Bowtell, D. and Holloway, A.: An expression-based site of origin diagnostic method designed for clinical application to cancer of unknown origin, Cancer Res 65, 2005, 4031-40
Varadhachary, G., Talantov, D., Raber, M., Meng, C., Hess, K., Jatkoe, T., Lenzi, R., Spigel, D., Wang, Y., Greco, F., Abbruzzese, J. and Hainsworth, J.: Molecular profiling of carcinoma of unknown primary and correlation with clinical evaluation, J Clin Oncol 26, 2008, 4442-8
Yeang, C., Ramaswamy, S., Tamayo, P., Mukherjee, S., Rifkin, R., Angelo, M., Reich, M., Lander, E., Mesirov, J. and Golub, T.: Molecular classification of multiple tumor types, Bioinformatics 17 Suppl 1, 2001, S. 316-22
Zikusoka, M., Kidd, M., Eick, G., Latich, I. and Modlin, 1.: The molecular genetics of gastroenteropancreatic neuroendocrine tumors, Cancer 104, 2005, 2292-309

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