DE102004023635A1 - Heteroarylsubstituierte Cyclohexyl-1,4-diamin-Derivate - Google Patents

Heteroarylsubstituierte Cyclohexyl-1,4-diamin-Derivate Download PDF

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Publication number
DE102004023635A1
DE102004023635A1 DE102004023635A DE102004023635A DE102004023635A1 DE 102004023635 A1 DE102004023635 A1 DE 102004023635A1 DE 102004023635 A DE102004023635 A DE 102004023635A DE 102004023635 A DE102004023635 A DE 102004023635A DE 102004023635 A1 DE102004023635 A1 DE 102004023635A1
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Germany
Prior art keywords
cyclohexyl
dimethylamino
phenyl
benzyl
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE102004023635A
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German (de)
English (en)
Inventor
Bernd Dr. Sundermann
Corinna Dr. Sundermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
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Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH
Priority to DE102004023635A priority Critical patent/DE102004023635A1/de
Priority to ES05759144T priority patent/ES2395430T3/es
Priority to EP05759144A priority patent/EP1745009B1/de
Priority to PT57591448T priority patent/PT1745009E/pt
Priority to SI200531621T priority patent/SI1745009T1/sl
Priority to PCT/EP2005/004911 priority patent/WO2005110971A1/de
Priority to CA2566212A priority patent/CA2566212C/en
Priority to PL05759144T priority patent/PL1745009T3/pl
Priority to DK05759144.8T priority patent/DK1745009T3/da
Priority to JP2007512031A priority patent/JP4982357B2/ja
Publication of DE102004023635A1 publication Critical patent/DE102004023635A1/de
Priority to US11/595,003 priority patent/US8093272B2/en
Priority to CY20121101271T priority patent/CY1113533T1/el
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
    • C—CHEMISTRY; METALLURGY
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    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
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    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
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DE102004023635A 2004-05-10 2004-05-10 Heteroarylsubstituierte Cyclohexyl-1,4-diamin-Derivate Withdrawn DE102004023635A1 (de)

Priority Applications (12)

Application Number Priority Date Filing Date Title
DE102004023635A DE102004023635A1 (de) 2004-05-10 2004-05-10 Heteroarylsubstituierte Cyclohexyl-1,4-diamin-Derivate
PCT/EP2005/004911 WO2005110971A1 (de) 2004-05-10 2005-05-06 Heteroarylsubstituierte cyclohexyl-1,4-diamin-derivate
EP05759144A EP1745009B1 (de) 2004-05-10 2005-05-06 Heteroarylsubstituierte cyclohexyl-1,4-diamin-derivate
PT57591448T PT1745009E (pt) 2004-05-10 2005-05-06 Derivados de ciclo-hexil-1,4-diamina substituídos com heteroarilo
SI200531621T SI1745009T1 (sl) 2004-05-10 2005-05-06 Heteroarilno substituirani derivati cikloheksil-1,4-diamina
ES05759144T ES2395430T3 (es) 2004-05-10 2005-05-06 Derivados de ciclohexil-1,4-diamina sustituidos con heteroarilo
CA2566212A CA2566212C (en) 2004-05-10 2005-05-06 Heteroaryl-substituted cyclohexyl-1,4-diamine derivatives
PL05759144T PL1745009T3 (pl) 2004-05-10 2005-05-06 Heteroarylopodstawione pochodne cykloheksylo-1,4-diamin
DK05759144.8T DK1745009T3 (da) 2004-05-10 2005-05-06 Heteroarylsubstituerede cyklohexyl-1,4-diamin-derivater
JP2007512031A JP4982357B2 (ja) 2004-05-10 2005-05-06 ヘテロアリール−置換されたシクロヘキシル−１，４−ジアミン誘導体
US11/595,003 US8093272B2 (en) 2004-05-10 2006-11-09 Heteroaryl substituted cyclohexyl-1,4-diamine compounds
CY20121101271T CY1113533T1 (el) 2004-05-10 2012-12-28 Ετεροαρυλο-υποκατεστημενα παραγωγα κυκλοεξυλο-1,4-διαμινης

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004023635A DE102004023635A1 (de) 2004-05-10 2004-05-10 Heteroarylsubstituierte Cyclohexyl-1,4-diamin-Derivate

Publications (1)

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DE102004023635A1 true DE102004023635A1 (de) 2006-04-13

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DE102004023635A Withdrawn DE102004023635A1 (de) 2004-05-10 2004-05-10 Heteroarylsubstituierte Cyclohexyl-1,4-diamin-Derivate

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US (1) US8093272B2 (https=)
EP (1) EP1745009B1 (https=)
JP (1) JP4982357B2 (https=)
CA (1) CA2566212C (https=)
CY (1) CY1113533T1 (https=)
DE (1) DE102004023635A1 (https=)
DK (1) DK1745009T3 (https=)
ES (1) ES2395430T3 (https=)
PL (1) PL1745009T3 (https=)
PT (1) PT1745009E (https=)
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EP1745009B1 (de) 2012-11-14
WO2005110971A1 (de) 2005-11-24
US8093272B2 (en) 2012-01-10
CY1113533T1 (el) 2016-06-22
CA2566212C (en) 2013-06-18
PL1745009T3 (pl) 2013-02-28
US20070129369A1 (en) 2007-06-07
JP2007536321A (ja) 2007-12-13
PT1745009E (pt) 2013-01-04
JP4982357B2 (ja) 2012-07-25
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