DE10157476B4 - Cosmetic and / or dermatological sunscreen preparation - Google Patents

Abstract

Cosmetic and / or dermatological composition for protection against UV radiation with 2,2'-methylenebis (6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) -phenol ) and coated powders consisting of a core of at least one siloxane elastomer selected from the group of siloxane elastomers obtainable either by reaction of vinyl-terminated polymethylsiloxane and methylhydrodimethylsiloxane or by reaction of hydroxy-terminated dimethylpolysiloxane and trimethylsiloxy-terminated methylpolysiloxane, said coating comprising a trimethylsiloxysilicate and / or whose derivative consists of silicon-bonded fluoroalkyl and / or phenyl groups, characterized in that the coated powders used are vinyl dimethicone / methicone silesquioxane crosspolymers and wherein 1 to 4% by weight of 2- (2H-benzotriazol-2-yl ) -4-methyl-6- [2-methyl-3- [1,3,3,3-tetramethyl-1 - [(tri-methylsilyl) oxy] disiloxanyl] -propyl] -phenol, 0.5 to 5, 25% by weight of 2,2'-methylene-bis (6- (2H-b enzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) phenol), the sum concentration of 2- (2H-benzotriazol-2-yl) -4-methyl-6- [2- methyl-3- [1,3,3,3-tetramethyl-1 - [(trimethylsilyl) oxy] disiloxanyl] propyl] phenol and 2,2'-methylenebis (6- (2H-benzotriazole-2-yl) yl) -4- (1,1,3,3-tetramethylbutyl) phenol) is at most 6% by weight and the siloxane elastomer is present in proportions of 0.5 to 12% by weight.

Description

The present invention relates to cosmetic and / or dermatological sunscreen formulations which have a particularly advantageous sensor technology. At the same time, the formulation acts synergistically with respect to the sun protection factors achieved. The formulations are useful for protecting the skin and / or hair from UV radiation and are applied by application to the skin or hair.

The damaging effect of the ultraviolet part of solar radiation on the skin is well known. Depending on their respective wavelength, the rays have different effects on the organ skin: The so-called UV-C radiation with a wavelength smaller than 290 nm is absorbed by the ozone layer in the earth's atmosphere and therefore has no physiological significance. In contrast, rays in the range between 290 nm and 320 nm, the so-called UV-B range, cause erythema, simple sunburn or even more or less severe burns. As a maximum of the erythema efficiency of sunlight, the narrower range around 308 nm is given.

For protection against UV-B radiation, numerous compounds are known, which are, for example, derivatives of 3-Benzylidencamphers, 4-aminobenzoic acid, cinnamic acid, salicylic acid and benzophenone.

It has long been erroneously assumed that the long-wave UV-A radiation having a wavelength between 320 nm and 400 nm has only a negligible biological effect. In the meantime, however, numerous studies have proven that UV-A radiation is far more dangerous than UV-B radiation with regard to triggering photodynamic, especially phototoxic reactions and chronic changes in the skin.

Also, the damaging effect of UV-B radiation can be enhanced by UV-A radiation.

So it is u. a. It has been proven that even under normal everyday conditions even UV-A radiation is sufficient to rapidly damage the collagen and elastin fibers, which are essential for the structure and firmness of the skin. This leads to chronic light-induced skin changes - the skin "ages" prematurely. The clinical appearance of light-aged skin includes, for example, wrinkles and wrinkles, and an irregular, ridged relief. Furthermore, the areas affected by photoaging may have irregular pigmentation. The formation of brown spots, keratoses and even carcinomas or malignant melanomas is possible. In addition, a prematurely aged skin due to the everyday UV exposure is characterized by a lower activity of the Langerhans cells and a slight, chronic inflammation.

About 90% of the ultraviolet radiation reaching the Earth consists of UVA rays. While UV-B radiation varies widely depending on many factors (eg, time of year, day or latitude), UV-A radiation remains relatively constant day and day regardless of year, daytime or geographical factors. At the same time, most of the UV-A radiation penetrates into the living epidermis, while about 70% of the UV-B rays are retained by the horny layer.

It is therefore of fundamental importance that cosmetic and dermatological sunscreen formulations provide adequate protection against both UV-B and UV-A radiation.

Also inorganic micropigments are suitable as light stabilizers. These act by reflecting the UVA and UVB rays on the skin surface. The particle sizes of the pigments are chosen so that the individual particles are no longer perceptible with the eye. For example, pigments based on metal oxides and / or other sparingly soluble or insoluble metal compounds, in particular the oxides of titanium (TiO ₂ ), zinc (ZnO), iron (eg Fe ₂ O ₃ ), zirconium (ZrO ₂ ), Silicon (SiO ₂ ), manganese (eg MnO), aluminum (Al ₂ O ₃ ), cerium (eg Ce ₂ O ₃ ), mixed oxides of the corresponding metals and mixtures of such oxides. In many cases, the inorganic pigments are used in hydrophobic form, ie that they are superficially treated water-repellent. This surface treatment may consist in providing the pigments with a thin hydrophobic layer according to methods known per se.

The use of powders of spherical silicone rubbers and elastomeric polyorganosiloxanes or organopolysiloxanes, hereinafter referred to as siloxane elastomers, and of powders of silicone resins in cosmetic preparations is known per se and has gained in importance in recent years.

oder auch durch Reaktion von Hydroxy-endständigem Dimethylpolysiloxan und Trimethylsiloxy-endständigem Methylpolysiloxan:

Siloxane elastomers are partially or completely crosslinked and usually have a three-dimensional structure. They are obtainable by a reaction of vinyl-terminated polymethylsiloxane and methylhydrodimethylsiloxane

or also by reaction of hydroxy-terminated dimethylpolysiloxane and trimethylsiloxy-terminated methylpolysiloxane:

These siloxane elastomers are used, for example, for adjusting the rheological properties of a preparation. Described are such siloxane elastomers, for example in the European Patent 295,886 as well as the U.S. Patent 5,266,321 which disclose the use of these substances in facial cleansers or oily make-up products. These documents also describe the nature of the siloxane elastomers in more detail.

auszeichnen, haben sich bewährt.Highly branched silicone resins have hitherto been used as silicone resins in cosmetics. In particular trimethylsiloxysilicates, which are defined by the formula

excel, have proven themselves.

However, the powders of siloxane elastomers or silicone resins also have disadvantages: For example, the powders of siloxane elastomers are poorly dispersible in cosmetic preparations, while the powders of silicone resins have unsatisfactory sensory properties. To overcome these disadvantages, silicone resin-coated powders of siloxane elastomers have been developed which have the CTFA designation Vinyl Dimethicone / Methicone Silesquioxane Crosspolymer. Suitable siloxane elastomers are the reaction products described above. The surface coating is carried out with trimethylsiloxysilikaten.

These can be characterized by their average particle size and particle size distribution and by their powder hardness. Average particle size and particle size distribution can be determined with a device for determining particle sizes by the method of static light control, for example, the company Malvern Mastersizer S type in water as a dispersant with a He-Ne laser at a wavelength of 632.8 nm and a laser power of 5 mW. In the following, the average particle size is to be understood as the number average as well as the particle size distribution of the Dv 50 value. The hardness of the powder (Hardness) is measured analogously to the Japanese standard JIS K6301 with a type A durometer.

Commercially available are the products under the trade designation KSP-100, KSP-101, KSP-102, KSP-103, KSP-104, KSP 106 from Shin-Etsu having a particle size distribution of 0.7-30 μm, an average particle size of 2 -30 μm and a Hardness of 30-75.

Derivatized vinyldimethicone / methicone silesquioxane crosspolymers are also obtainable, for example with phenyl groups or with fluoroalkyl groups. These are characterized by a reduced swelling capacity in silicone oils. Commercially available are the fluoroalkyl functionalized hybrid silicone powder products available under the trade designation KSP-200 from Shin-Etsu. The phenyl group-functionalized hybrid silicone powder is available under the trade name KSP-300 from Shin-Etsu. Common commercial products such as KSP-200, 300 have a particle size distribution of 0.7-13 μm, an average particle size of 2-8 μm, preferably 5 μm, and a hardness of 20-50. If these siloxane elastomers are coated with silicone resins, improved dispersibility, good formulation flexibility with light-protection filters and cosmetically sensorike properties are achieved. The object of the present invention was to provide cosmetic and / or dermatological sunscreen preparations which do not have the disadvantages of the prior art and in particular have high sun protection factors, good long-term storage stabilities, pleasant sensory properties and improved water resistance. The object is surprisingly achieved by a cosmetic and / or dermatological preparation according to claim 1. It is particularly preferred if the particles of the coated powders have a particle size distribution of 0.7 to 30 .mu.m and an average particle size of 2 to 30 .mu.m and a powder hardness of 30 to 75.

Although the prior art knows the pamphlets DE 199 39 836 A1 . WO 902/003 951 A2 . WO 98/00 1004 A1 and EP 1 062 944 A1 However, these writings could not point the way to the present invention. Furthermore, it is preferred if the coated powders are used in combination with oils of hydrocarbons of animal and / or vegetable origin, synthetic oils, synthetic esters, synthetic ethers or mixtures thereof. In this case, it is particularly preferred if the coated powders are used in combination with unbranched silicone oils or cyclic silicone oils or mixtures thereof which are liquid or pasty at room temperature. It is very particularly preferred if the content of the coated powders in the preparation is 0.3 to 60% by weight. It is very particularly preferred if the preparation contains at least one further UV filter substance selected from the group consisting of triazines, aminobenzophenones, the UV filter which is liquid at room temperature, sulfonated, water-soluble UV filters, oil-soluble UV rub-through filters and organic and / or inorganic pigments which are preferably surface-treated contains. It is further preferred if the preparation additionally contain inorganic micropigments. It is particularly preferred if metal oxides having an average particle size of 10 to 100 nm are used as the inorganic micropigment. It is very particularly preferred if oxides of titanium, iron, zinc, zirconium or cerium are used as inorganic micropigments. It is exceptionally particularly preferred if metal oxides coated as inorganic micropigments are used. It is exceptionally particularly particularly preferred if the inorganic micropigments are present in a proportion of 0.5 to 30% by weight.

Preference is given to using the preparations according to the invention for protecting the skin or hair from UV light, damage caused by UV light and aging phenomena caused by UV light.

• – ungewöhnliche sensorische Eigenschaften aufweisen, indem sie geschmeidig und dabei reichhaltig wirken, aber dennoch keinen fettigen Rückstand auf der Haut hinterlassen,
• – gegenüber für O/W-Emulsionen charakteristischer Haptik eine vorteilhafte Konsistenzverbesserung aufweisen,
• – eine synergistische Erhöhung der Lichtschutzwirkung zeigen,
• – erhöhte UV-A-Filterwirkung haben,
• – eine höhere Wasserfestigkeit bieten,
• – besser der Hautaustrocknung entgegenwirken,

als die Zubereitungen des Standes der Technik.The preparations according to the invention are extremely satisfactory preparations in every respect. It was not foreseeable for the skilled person that the preparations according to the invention

• - have unusual sensory properties, by being supple and rich, yet leaving no greasy residue on the skin,
• - have a favorable texture improvement compared with the feel characteristic of O / W emulsions,
• Show a synergistic increase in the light protection effect,
• - have increased UV-A filtering effect,
• - offer a higher water resistance,
• - better counteract skin dehydration,

as the preparations of the prior art.

• – von lichtbedingten Hautschäden
• – von entzündlichen Hautzuständen sowie atopischem Ekzem, seborrhoischem Ekzem, polymorpher Lichtdermatose, Psoriasis, Vitiligo

möglich.When applying the preparations according to the invention is surprisingly an effective treatment, but also a prophylaxis

• - of light-induced skin damage
• - of inflammatory skin conditions as well as atopic eczema, seborrheic eczema, polymorphic photodermatosis, psoriasis, vitiligo

possible.

• a) Partialfettsäureester und Fettsäureester mehrwertiger Alkohole und deren ethoxylierte Derivate (z. B. Glycerylmonostearate, Sorbitanstearate, Glycerylstearylcitrate, Sucrosestearate)
• b) ethoxilierte Fettalkohole und Fettsäuren
• c) ethoxilierte Fettamine, Fettsäureamide, Fettsäurealkanolamide
• d) Alkylphenolpolyglycolether (z. B. Triton X)

It is of advantage in the formulations of the invention coated powders of a core of at least one siloxane elastomer selected from the group of siloxane elastomers obtainable either by reaction of vinyl-terminated polymethylsiloxane and methylhydrodimethylsiloxane or by reaction of hydroxy-terminated dimethylpolysiloxane and trimethylsiloxy-terminated methylpolysiloxane, wherein the coating of a trimethylsiloxy silicate and / or its derivative offered by the company Shin-Etsu under the designation KSP-100, KSP-101, KSP-102, KSP-103, KSP-104, KSP-106. Preparations according to the invention present as emulsions contain one or more emulsifiers. These emulsifiers can be advantageously selected from the group of nonionic, anionic, cationic or amphoteric emulsifiers. Among the nonionic emulsifiers are

• a) Partial fatty acid esters and fatty acid esters of polyhydric alcohols and their ethoxylated derivatives (eg glyceryl monostearates, sorbitan stearates, glyceryl stearyl citrates, sucrose stearates)
• b) ethoxylated fatty alcohols and fatty acids
• c) ethoxylated fatty amines, fatty acid amides, fatty acid alkanolamides
• d) alkylphenol polyglycol ethers (eg Triton X)

• a) Seifen (z. B. Natriumstearat)
• b) Fettalkoholsulfate
• c) Mono-, Di- und Trialkylphosphosäureester und deren Ethoxylate

Among the anionic emulsifiers are

• a) soaps (eg sodium stearate)
• b) fatty alcohol sulfates
• c) mono-, di- and Trialkylphosphosäureester and their ethoxylates

• a) quaternäre Ammoniumverbindungen mit einem langkettigen aliphatischen Rest z. B. Distearyldimonium Chloride

Among the cationic emulsifiers are

• a) quaternary ammonium compounds with a long-chain aliphatic radical z. B. distearyldimonium chlorides

• a) Alkylamininoalkancarbonsäuren
• b) Betaine, Sulfobetaine
• c) Imidazolinderivate

Among the amphoteric emulsifiers are

• a) Alkylamininoalkanecarboxylic acids
• b) betaines, sulfobetaines
• c) imidazoline derivatives

Furthermore, there are naturally occurring emulsifiers, which include beeswax, wild boar, lecithin and sterols.

• – der Fettalkoholethoxylate
• – der ethoxylierten Wollwachsalkohole,
• – der Polyethylenglycolether der allgemeinen Formel R-O-(-CH₂-CH₂-O-)_n-R',
• – der Fettsäureethoxylate der allgemeinen Formel R-COO-(-CH₂-CH₂-O-)_n-H,
• – der veretherten Fettsäureethoxylate der allgemeinen Formel R-COO-(-CH₂-CH₂-O-)_n-R',
• – der veresterten Fettsäureethoxylate der allgemeinen Formel R-COO-(-CH₂-CH₂-O-)_n-C(O)-R',
• – der Polyethylenglycolglycerinfettsäureester
• – der ethoxylierten Sorbitanester
• – der Cholesterinethoxylate
• – der ethoxylierten Triglyceride
• – der Alkylethercarbonsäuren der allgemeinen Formel R-O-(-CH₂-CH₂-O-)_n-CH₂-COOH nd n eine Zahl von 5 bis 30 darstellen,
• – der Polyoxyethylensorbitolfettsäureester,
• – der Alkylethersulfate der allgemeinen Formel R-O-(-CH₂-CH₂-O-)_n-SO₃-H
• – der Fettalkoholpropoxylate der allgemeinen Formel R-O-(-CH₂-CH(CH₃)-O-)_n-H,
• – der Polypropylenglycolether der allgemeinen Formel R-O-(-CH₂-CH(CH₃)-O-)_n-R',
• – der propoxylierten Wollwachsalkohole,
• – der veretherten Fettsäurepropoxylate R-COO-(-CH₂-CH(CH₃)-O-)_n-R',
• – der veresterten Fettsäurepropoxylate der allgemeinen Formel R-COO-(-CH₂-CH(CH₃)-O-)n-C(O)-R',
• – der Fettsäurepropoxylate der allgemeinen Formel R-COO-(-CH₂-CH(CH₃)-O-)_n-H,
• – der Polypropylenglycolglycerinfettsäureester
• – der propoxylierten Sorbitanester
• – der Cholesterinpropoxylate
• – der propoxylierten Triglyceride
• – der Alkylethercarbonsäuren der allgemeinen Formal R-O-(-CH₂-CH(CH₃)O-)_n-CH₂-COOH
• – der Alkylethersulfate bzw. die diesen Sulfaten zugrundeliegenden Säuren der allgemeinen Formeql R-O-(-CH₂-CH(CH₃)-O-)_n-SO₃-H
• – der Fettalkoholethoxylate/propoxylate der allgemeinen Formel R-O-X_n-Y_m-H,
• – der Polypropylenglycolether der allgemeinen Formel R-O-X_n-Y_m-R',
• – der veretherten Fettsäurepropoxylate der allgemeinen Formel R-COO-X_n-Y_m-R',
• – der Fettsäureethoxylate/propoxylate der allgemeinen Formel R-COO-X_n-Y_m-H,.

For example, O / W emulsifiers can be advantageously selected from the group of polyethoxylated or polypropoxylated or polyethoxylated and polypropoxylated products, eg. B .:

• - the fatty alcohol ethoxylates
• - the ethoxylated wool wax alcohols,
• The polyethylene glycol ether of the general formula RO - (- CH ₂ -CH ₂ -O-) _n -R ',
• The fatty acid ethoxylates of the general formula R-COO - (- CH ₂ -CH ₂ -O-) _n -H,
• The etherified fatty acid ethoxylates of the general formula R-COO - (- CH ₂ -CH ₂ -O-) _n -R ',
• - the esterified fatty acid ethoxylates of the general formula R-COO - (- CH ₂ -CH ₂ -O-) _n -C (O) -R ',
• - The Polyethylenglycolglycerinfettsäureester
• - the ethoxylated sorbitan ester
• - the cholesterol ethoxylates
• - the ethoxylated triglycerides
• The alkyl ether carboxylic acids of the general formula RO - (- CH ₂ -CH ₂ -O-) _n -CH ₂ -COOH nd n represent a number from 5 to 30,
• The polyoxyethylene sorbitol fatty acid ester,
• The alkyl ether sulfates of the general formula RO - (- CH ₂ -CH ₂ -O-) _n -SO ₃ -H
• The fatty alcohol propoxylates of the general formula RO - (- CH ₂ -CH (CH ₃ ) -O-) _n -H,
• The polypropylene glycol ether of the general formula RO - (- CH ₂ -CH (CH ₃ ) -O-) _n -R ',
• The propoxylated wool wax alcohols,
• - the etherified fatty acid propoxylates R-COO - (- CH ₂ -CH (CH ₃ ) -O-) _n -R ',
• - the esterified fatty acid propoxylates of the general formula R-COO - (- CH ₂ -CH (CH ₃ ) -O-) nC (O) -R ',
• The fatty acid propoxylates of the general formula R-COO - (- CH ₂ -CH (CH ₃ ) -O-) _n -H,
• The polypropylene glycol glycerin fatty acid ester
• - the propoxylated sorbitan ester
• - the cholesterol propoxylates
• - the propoxylated triglycerides
• The alkyl ether carboxylic acids of general formula RO - (- CH ₂ -CH (CH ₃ ) O-) _n -CH ₂ -COOH
• The alkyl ether sulfates or the acids based on these sulfates of the general formula RO - (- CH ₂ -CH (CH ₃ ) -O-) _n -SO ₃ -H
• The fatty alcohol ethoxylates / propoxylates of the general formula ROX _n -Y _m -H,
• The polypropylene glycol ether of the general formula ROX _n -Y _m -R ',
• - etherified fatty acid propoxylates of the general formula R-COO-X _n -Y _m -R ',
• - The fatty acid ethoxylates / propoxylates of the general formula R-COO-X _n -Y _m -H ,.

According to the invention, the polyethoxylated or polypropoxylated or polyethoxylated and polypropoxylated O / W emulsifiers used are particularly advantageously selected from the group of substances having HLB values of 11-18, very particularly advantageously having HLB values of 14.5-15, 5, provided that the O / W emulsifiers have saturated radicals R and R '. If the O / W emulsifiers have unsaturated radicals R and / or R ', or if isoalkyl derivatives are present, the preferred HLB value of such emulsifiers may also be lower or higher.

It is advantageous to choose the fatty alcohol ethoxylates from the group of ethoxylated stearyl alcohols, cetyl alcohols, cetylstearyl alcohols (cetearyl alcohols). Particularly preferred are:
Polyethylene glycol (13) stearyl ether (steareth-13), polyethylene glycol (14) stearyl ether (steareth-14), polyethylene glycol (15) stearyl ether (steareth-15), polyethylene glycol (16) stearyl ether (steareth-16), polyethylene glycol (17) stearyl ether ( Steareth-17), polyethylene glycol (18) stearyl ether (steareth-18), polyethylene glycol (19) stearyl ether (steareth-19), polyethylene glycol (20) stearyl ether (steareth-20),
Polyethylene glycol (12) isostearyl ether (isosteareth-12), polyethylene glycol (13) isostearyl ether (isosteareth-13), polyethylene glycol (14) isostearyl ether (isosteareth-14), polyethylene glycol (15) isostearyl ether (isosteareth-15), polyethylene glycol (16) isostearyl ether ( Isosteareth-16), polyethylene glycol (17) isostearyl ether (isosteareth-17), polyethylene glycol (18) isostearyl ether (isosteareth-18), polyethylene glycol (19) isostearyl ether (isosteareth-19), polyethylene glycol (20) isostearyl ether (isosteareth-20),
Polyethylene glycol (13) Cetyl ether (Ceteth-13), Polyethylene glycol (14) Cetyl ether (Ceteth-14), Polyethylene glycol (15) Cetyl ether (Ceteth-15), Polyethylene glycol (16) Cetyl ether (Ceteth-16), Polyethylene glycol (17) Cetyl ether ( Ceteth-17), polyethylene glycol (18) cetyl ether (ceteth-18), polyethylene glycol (19) cetyl ether (ceteth-19), polyethylene glycol (20) cetyl ether (ceteth-20),
Polyethylene glycol (13) isocetyl ether (isoceteth-13), polyethylene glycol (14) isocetyl ether (isoceteth-14), polyethylene glycol (15) isocetyl ether (isoceteth-15), polyethylene glycol (16) isocetyl ether (isoceteth-16), polyethylene glycol (17) isocetyl ether ( Isoceteth-17), polyethylene glycol (18) isocetyl ether (isoceteth-18), polyethylene glycol (19) isocetyl ether (isoceteth-19), polyethylene glycol (20) isocetyl ether (isoceteth-20),
Polyethylene glycol (12) oleyl ether (Oleth-12), polyethylene glycol (13) oleyl ether (Oleth-13), polyethylene glycol (14) oleyl ether (Oleth-14), polyethylene glycol (15) oleyl ether (Oleth-15),
Polyethylene glycol (12) lauryl ether (Laureth-12), polyethylene glycol (12) isolauryl ether (Isolaureth-12).

Polyethylene glycol (13) cetyl stearyl ether (ceteareth-13), polyethylene glycol (14) cetyl stearyl ether (ceteareth-14), polyethylene glycol (15) cetyl stearyl ether (ceteareth-15), polyethylene glycol (16) cetyl stearyl ether (ceteareth-16), polyethylene glycol (17) cetyl stearyl ether ( Ceteareth-17), polyethylene glycol (18) cetyl stearyl ether (ceteareth-18), polyethylene glycol (19) cetyl stearyl ether (ceteareth-19), polyethylene glycol (20) cetyl stearyl ether (ceteareth-20).

It is also advantageous to choose the fatty acid ethoxylates from the following group:
Polyethylene glycol (20) stearate, polyethylene glycol (21) stearate, polyethylene glycol (22) stearate, polyethylene glycol (23) stearate, polyethylene glycol (24) stearate, polyethylene glycol (25) stearate,
Polyethylene glycol (12) isostearate, polyethylene glycol (13) isostearate, polyethylene glycol (14) isostearate, polyethylene glycol (15) isostearate, polyethylene glycol (16) isostearate, polyethylene glycol (17) isostearate, polyethylene glycol (18) isostearate, polyethylene glycol (19) isostearate, polyethylene glycol (20) isostearate, polyethylene glycol (21) isostearate, polyethylene glycol (22) isostearate, polyethylene glycol (23) isostearate, polyethylene glycol (24) isostearate, polyethylene glycol (25) isostearate,
Polyethylene glycol (12) oleate, polyethylene glycol (13) oleate, polyethylene glycol (14) oleate, polyethylene glycol (15) oleate, polyethylene glycol (16) oleate, polyethylene glycol (17) oleate, polyethylene glycol (18) oleate, polyethylene glycol (19) oleate, polyethylene glycol ( 20) oleate

As the ethoxylated alkyl ether carboxylic acid or its salt, the sodium laureth-11-carboxylate can be advantageously used.

As the alkyl ether sulfate, sodium laureth 1-4 sulfate can be advantageously used.

As the ethoxylated cholesterol derivative, polyethylene glycol (30) cholesteryl ether can be advantageously used. Also polyethylene glycol (25) soybean oil has been proven.

As ethoxylated triglycerides, the polyethylene glycol (60) Evening Primrose Glycerides can advantageously be used (Evening Primrose = evening primrose)

It is furthermore advantageous to use the polyethylene glycol glycerol fatty acid esters from the group consisting of polyethylene glycol (20) glyceryl laurate, polyethylene glycol (21) glyceryl laurate, polyethylene glycol (22) glyceryl laurate, polyethylene glycol (23) glyceryl laurate, polyethylene glycol (6) glyceryl caprate / caprate, polyethylene glycol (20) glyceryl oleate, polyethylene glycol ( 20) glyceryl isostearate, polyethylene glycol (18) glyceryl oleate / cocoate.

It is also convenient to select the sorbitan esters from the group of polyethylene glycol (20) sorbitan monolaurate, polyethylene glycol (20) sorbitan monostearate, polyethylene glycol (20) sorbitan monoisostearate, polyethylene glycol (20) sorbitan monopalmitate, polyethylene glycol (20) sorbitan monooleate.

As advantageous W / O emulsifiers can be used: fatty alcohols having 8 to 30 carbon atoms, monoglycerol esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids having a chain length of 8 to 24, in particular 12-18 carbon atoms, diglycerol esters saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids having a chain length of 8 to 24, in particular 12-18, carbon atoms, monoglycerol ethers of saturated and / or unsaturated, branched and / or unbranched alcohols having a chain length of 8 to 24, in particular 12-18 C Atoms, diglycerol ethers of saturated and / or unsaturated, branched and / or unbranched alcohols of a chain length of 8 to 24, in particular 12-18 C-atoms, propylene glycol esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids of a chain length of 8 to 24, in particular 12-18 C atoms and sorbitan esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids of a chain length of 8 to 24, in particular 12-18 C-atoms.

Particularly advantageous W / O emulsifiers are glyceryl monostearate, glyceryl, glyceryl monomyristate, glyceryl, diglyceryl monostearate, Diglycerylmonoisostearat, propylene glycol, propylene glycol monoisostearate, propylene glycol monocaprylate, propylene glycol, sorbitan, sorbitan, sorbitan, Sorbitanmonoisooleat, sucrose, cetyl alcohol, stearyl, arachidyl, behenyl, Isobehenylalkohol, selachyl, Chimyl alcohol, polyethylene glycol (2) stearyl ether (steareth-2), glyceryl monolaurate, glyceryl monocaprinate, glyceryl monocaprylate.

Also favorable are those cosmetic and dermatological preparations which are in the form of a sunscreen. In addition to the active compound combinations according to the invention, these preferably additionally contain at least one UV-A filter substance and / or at least one UV-B filter substance and / or at least one inorganic pigment.

However, it is also advantageous in the context of the present inventions to prepare such cosmetic and dermatological preparations whose main purpose is not the protection from sunlight, but which nevertheless contain a content of UV protective substances. So z. B. in day creams usually UV-A or UV-B filter substances incorporated.

Also, UV protectants, as well as antioxidants and, if desired, preservatives, provide effective protection of the preparations themselves against spoilage.

Worteilhaft containing formulations of the invention, the substances which absorb UV radiation in the UV-A and / or UV-B range, in a total amount of z. B. 0.1 wt .-% to 30 wt .-%, preferably 0.5 to 20 wt .-%, in particular 1.0 to 15.0 wt .-%, each based on the total weight of the preparations to cosmetic To provide preparations that protect the hair or the skin from the entire range of ultraviolet radiation. They can also serve as a sunscreen for hair or skin.

Accordingly, the preparations according to the present invention preferably contain at least one UV-A and / or UV-B filter substance. The formulations may, although not necessary, optionally also contain one or more organic and / or inorganic pigments as UV filter substances, which may be present in the water and / or the oil phase.

Preferred inorganic pigments are metal oxides and / or other water-insoluble or insoluble metal compounds, in particular oxides of titanium (TiO ₂ ), zinc (ZnO), iron (eg Fe ₂ O ₃ ), zirconium (ZrO ₂ ), silicon ( SiO ₂ ), manganese (for example MnO), aluminum (Al ₂ O ₃ ), cerium (for example Ce ₂ O ₃ ), mixed oxides of the corresponding metals and mixtures of such oxides, and the barium sulfate (BaSO 4) ₄ ).

The titanium dioxide pigments can be present both in the rutile and anatase crystal modifications and can advantageously be surface-treated ("coated") for the purposes of the present invention, with a hydrophilic, amphiphilic or hydrophobic character, for example, being or being retained. This surface treatment may consist in providing the pigments with a thin hydrophilic and / or hydrophobic inorganic and / or organic layer by processes known per se. The various surface coating can also contain water for the purposes of the present invention.

Inorganic surface coatings for the purposes of the present invention may consist of aluminum oxides (Al ₂ O ₃ ), aluminum hydroxides Al (OH) ₃ , sodium hexa metaphosphate (NaPO ₃ ) ₆ , sodium metaphosphate (NaPO ₃ ) _n , silicon dioxides (SiO ₂ ) (also: Silica, CAS No .: 7631-86-9), aluminum oxides (Al ₂ O ₃ ), aluminum hydroxides Al (OH) ₃ or alumina hydrate (also: alumina, CAS No .: 1333-84-2), or iron oxide (Fe ₂ O ₃ ). These inorganic surface coatings may be present alone, in combination and / or in combination with organic coating materials.

Organic surface coatings according to the present invention may consist of vegetable or animal aluminum stearates, vegetable or animal stearic acid, lauric acid, dimethylpolysiloxane (also: dimethicone), methylpolysiloxane (methicone), simethicone (a mixture of dimethylpolysiloxane with a average chain length of from 200 to 350 dimethylsiloxane units and silica gel) or alginic acid (algic acid). These organic surface coatings may be present alone, in combination and / or in combination with inorganic coating materials.

Coated and uncoated titanium dioxides described in the present invention may also be used in the form of commercially available oily or aqueous predispersions. Dispersants and / or solubilizers may advantageously be added to these predispersions.

Suitable titanium dioxide particles and predispersions of titanium dioxide particles are available from the following companies under the following trade names: trade name coating Manufacturer MT-100TV Aluminum hydroxide / stearic acid Tayca Corporation MT-100Z Aluminum hydroxide / stearic acid Tayca Corporation Eusolex T-2000 Alumina / Simethicone Merck KgaA Titanium Dioxide T805 (Uvinul TiO ₂ ) octyltrimethylsilane Degussa

Zinc oxide particles which are suitable according to the invention and predispersions of zinc oxide particles are obtainable from the companies listed below under the following trade name designations: trade name coating Manufacturer Z-Cote HP1 2% Dimethicone BASF Z-Cote / BASF ZnO NDM 5% Dimethicone MR

Advantageously, preparations according to the invention contain substances which absorb UV radiation in the UV-A and / or UV-B range, the total amount of the filter substances being e.g. B. 0.1 wt .-% to 30 wt .-%, preferably 0.5 to 20 wt .-%, in particular 1.0 to 15.0 wt .-%, based on the total weight of the preparations to cosmetic To provide preparations that protect the hair or the skin from the entire range of ultraviolet radiation. They can also serve as a sunscreen for hair or skin.

Advantageous UV-A filter substances for the purposes of the present invention are dibenzoylmethane derivatives, in particular 4- (tert-Buryl) -4'-methoxydibenzoylmethane (CAS-Nr. 70356-09-1), marketed by Givaudan under the trade name Parsol ^® 1789 and is sold by Merck under the trade name Eusolex ^® 9020th

und ihre Salze, besonders die entsprechenden Natrium-, Kalium- oder Triethanolammonium-Salze, insbesondere das Phenylen-1,4-bis-(2-benzimidazyl)-3,3'-5,5'-tetrasulfonsäure-bis-natriumsalz

mit der INCI-Bezeichnung Bisimidazylate, welches beispielsweise unter der Handelsbezeichnung Neo Heliopan AP bei Haarmann & Reimer erhältlich ist.Further advantageous UV-A filter substances are the phenylene-1,4-bis (2-benzimidazyl) -3,3'-5,5'-tetrasulfonic acid

and their salts, especially the corresponding sodium, potassium or triethanolammonium salts, especially the phenylene-1,4-bis (2-benzimidazyl) -3,3'-5,5'-tetrasulfonic acid bis-sodium salt

with the INCI name bisimidazylate, which is available, for example, under the trade name Neo Heliopan AP from Haarmann & Reimer.

gekennzeichnet ist. Dieses trägt die chemische Bezeichnung 2-(4'-(Diethylamino)-2'-hydoxybenzoyl)-benzoesäurehexylester.Also advantageous is the aminobenzophenone, which by the chemical structural formula

is marked. This carries the chemical name 2- (4 '- (diethylamino) -2'-hydroxybenzoyl) -benzoesäurhexylester.

Also advantageous are the 1,4-di (2-oxo-10-sulfo-3-bomylidenemethyl) benzene and its salts (especially the corresponding 10-sulfato compounds, in particular the corresponding sodium, potassium or triethanolammonium salt) which is also referred to as benzene-1,4-di (2-oxo-3-bomylidenemethyl-10-sulfonic acid) and is characterized by the following structure:

Advantageous UV filter substances in the context of the present invention are also so-called broadband filters, d. H. Filter substances that absorb both UV-A and UV-B radiation.

wobei R¹, R², und R³ unabhängig voneinander gewählt werden aus der Gruppe der verzweigten und unverzweigten Alkylgruppen mit 1 bis 10 Kohlenstoffatomen bzw. ein einzelnes Wasserstoffatom darstellen. Insbesondere bevorzugt sind das 2,4-Bis-{[4-(2-Ethyl-hexyloxy)-2-hydroxy)-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazin (INCI: Aniso Triazin), welches unter der Handelsbezeichnung Tinosorb^® S bei der CIBA-Chemikalien GmbH erhältlich ist.Advantageous broadband filters or UV-B filter substances are, for example, bis-resorcinyl triazine derivatives having the following structure:

wherein R ¹ , R ² , and R ^{3 are} independently selected from the group of branched and unbranched alkyl groups having 1 to 10 carbon atoms or represent a single hydrogen atom. Particularly preferred are 2,4-bis - {[4- (2-ethyl-hexyloxy) -2-hydroxy) -phenyl} -6- (4-methoxyphenyl) -1,3,5-triazine (INCI: aniso triazine ), which is available from CIBA-Chemikalien GmbH under the trade name Tinosorb ^® S in.

Particularly advantageous preparations according to the present invention, which are distinguished by a high or very high UV-A protection, preferably contain a plurality of UV-A and / or broadband filters, in particular dibenzoylmethane derivatives [for example the 4- (tert-butyl) 4'-methoxydibenzoylmethane], benzotriazole derivatives [for example, 2,2'-methylenebis (6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) -phenol)] , Phenylene-1,4-bis (2-benzimidazyl) -3,3'-5,5'-tetrasulfonic acid and / or its salts, the 1,4-di (2-oxo-10-sulfo-3-bomylidenemethyl ) Benzene and / or its salts and / or the 2,4-bis - {[4- (2-ethyl-hexyloxy) -2-hydroxy] -phenyl} -6- (4-methoxyphenyl) -1,3, 5-triazine, individually or in any combination with each other.

aufweisen, sind vorteilhafte UV-Filtersubstanzen im Sinne der vorliegenden Erfindung, beispielsweise die in der Europäischen Offenlegungsschrift EP 570 838 A1 beschriebenen s-Triazinderivate, deren chemische Struktur durch die generische Formel

wiedergegeben wird, wobei
R einen verzweigten oder unverzweigten C₁-C₁₅-Alkylrest, einen C₅-C₁₂-Cycloalkylrest, gegebenenfalls substituiert mit einer oder mehreren C₁-C₄-Alkylgruppen, darstellt,
X ein Sauerstoffatom oder eine NH-Gruppe darstellt,
R₁ einen verzweigten oder unverzweigten C₁-C₁₈-Alkylrest, einen C₅-C₁₂-Cycloalkylrest, gegebenenfalls substituiert mit einer oder mehreren C₁-C₄-Alkylgruppen, oder ein Wasserstoffatom, ein Alkalimetallatom, eine Ammoniumgruppe oder eine Gruppe der Formel

bedeutet, in welcher
A einen verzweigten oder unverzweigten C₁-C₁₈-Alkylrest, einen C₅-C₁₂-Cycloalkyl- oder Arylrest darstellt, gegebenenfalls substituiert mit einer oder mehreren C₁-C₄-Alkylgruppen,
R₃ ein Wasserstoffatom oder eine Methylgruppe darstellt,
n eine Zahl von 1 bis 10 darstellt,
R₂ einen verzweigten oder unverzweigten C₁-C₁₈-Alkylrest, einen C₅-C₁₂-Cycloalkylrest, gegebenenfalls substituiert mit einer oder mehreren C₁-C₄-Alkylgruppen, darstellt, wenn X die NH-Gruppe darstellt, und
einen verzweigten oder unverzweigten C₁-C₁₈-Alkylrest, einen C₅-C₁₂-Cycloalkylrest, gegebenenfalls substituiert mit einer oder mehreren C₁-C₄-Alkylgruppen, oder ein Wasserstoffatom, ein Alkalimetallatom, eine Ammoniumgruppe oder eine Gruppe der Formel

bedeutet, in welcher
A einen verzweigten oder unverzweigten C₁-C₁₈-Alkylrest, einen C₅-C₁₂-Cycloalkyl- oder Arylrest darstellt, gegebenenfalls substituiert mit einer oder mehreren C₁-C₄-Alkylgruppen,
R₃ ein Wasserstoffatom oder eine Methylgruppe darstellt,
n eine Zahl von 1 bis 10 darstellt,
wenn X ein Sauerstoffatom darstellt.Other UV filter substances, which are the structural motif

have advantageous UV filter substances in the sense of the present invention, for example, those in the European published patent application EP 570 838 A1 described s-triazine derivatives, their chemical structure by the generic formula

is reproduced, wherein
R is a branched or unbranched C ₁ -C ₁₅ -alkyl radical, a C ₅ -C ₁₂ -cycloalkyl radical, optionally substituted by one or more C ₁ -C ₄ -alkyl groups,
X represents an oxygen atom or an NH group,
R _{1 is} a branched or unbranched C ₁ -C ₁₈ alkyl radical, a C ₅ -C ₁₂ cycloalkyl radical optionally substituted with one or more C ₁ -C ₄ alkyl groups, or a hydrogen atom, an alkali metal atom, an ammonium group or a group of formula

means in which
A is a branched or unbranched C ₁ -C ₁₈ -alkyl radical, a C ₅ -C ₁₂ -cycloalkyl or aryl radical, optionally substituted by one or more C ₁ -C ₄ -alkyl groups,
R _{3 represents} a hydrogen atom or a methyl group,
n represents a number from 1 to 10,
R _{2 is} a branched or unbranched C ₁ -C ₁₈ alkyl radical, a C ₅ -C ₁₂ cycloalkyl radical optionally substituted with one or more C ₁ -C ₄ alkyl groups, when X represents the NH group, and
a branched or unbranched C ₁ -C ₁₈ alkyl radical, a C ₅ -C ₁₂ cycloalkyl radical optionally substituted with one or more C ₁ -C ₄ alkyl groups, or a hydrogen atom, an alkali metal atom, an ammonium group or a group of the formula

means in which
A is a branched or unbranched C ₁ -C ₁₈ -alkyl radical, a C ₅ -C ₁₂ -cycloalkyl or aryl radical, optionally substituted by one or more C ₁ -C ₄ -alkyl groups,
R _{3 represents} a hydrogen atom or a methyl group,
n represents a number from 1 to 10,
when X represents an oxygen atom.

wiedergegeben wird, welches im Folgenden auch als Dioctylbutylamidotriazon (INCI: Dioctylbutamidotriazone) bezeichnet wird und unter der Handelsbezeichnung UVASORB HEB bei Sigma 3 V erhältlich ist.Particularly preferred UV filter substance in the context of the present invention is also an unsymmetrically substituted s-triazine whose chemical structure is represented by the formula

which is also referred to below as Dioctylbutylamidotriazon (INCI: Dioctylbutamidotriazone) and is available under the trade name UVASORB HEB Sigma 3 V.

Also advantageous for the purposes of the present invention is a symmetrically substituted s-triazine, the 4,4 ', 4''- (1,3,5-triazine-2,4,6-triyltriimino) tris-benzoic acid tris (2 ethylhexyl ester), synonym: 2,4,6-tris [anilino- (p-carbo-2'-ethyl-1'-hexyloxy)] - 1,3,5-triazine (INCI: octyl triazone), which was obtained from BASF Aktiengesellschaft is marketed under the trade name Uvinul ^® T 150th

wiedergegeben wird, wobei R₁, R₂ und A₁ verschiedenste organische Reste repräsentieren.Also in the European Patent Application 775,698 are preferably used bis-Resorcinyltriazinderivate described their chemical structure by the generic formula

is reproduced, wherein R ₁ , R ₂ and A _{1 represent a} variety of organic radicals.

Also advantageous for the purposes of the present invention are 2,4-bis - {[4- (3-sulfonato) -2-hydroxy-propyloxy) -2-hydroxy] -phenyl} -6- (4-methoxyphenyl) -1, 3,5-triazine sodium salt containing 2,4-bis - {[4- (3- (2-propyloxy) -2-hydroxy-propyloxy) -2-hydroxy] -phenyl} -6- (4-methoxyphenyl) - 1,3,5-triazine, the 2,4-bis - {[4- (2-ethyl-hexyloxy) -2-hydroxy] -phenyl} -6- [4- (2-methoxyethylcarboxyl) -phenylamino] -1 , 3,5-trazin, which is 2,4-bis - {[4- (3- (2-propyloxy) -2-hydroxy-propyloxy) -2-hydroxy] -phenyl} -6- [4- (2- ethyl-carboxyl) -phenylamino] -1,3,5-triazine which is 2,4-bis - {(4- (2-ethyl-hexyloxy) -2-hydroxy] -phenyl} -6- (1-methyl) pyrrol-2-yl) -1,3,5-triazine, which is 2,4-bis - {[4-tris (trimethylsiloxy-silylpropyloxy) -2-hydroxy] -phenyl} -β- (4-methoxyphenyl) -1 , 3,5-triazine, the 2,4-bis - {[4- (2 '' - methylpropenyloxy) -2-hydroxy] -phenyl} -6- (4-methoxyphenyl) -1,3,5-triazine and the 2,4-bis - {[4- (1 ', 1', 1 ', 3', 5 ', 5', 5'-heptamethylsiloxy-2 "-methyl-propyloxy) -2-hydroxy] -phenyl } -6- (4-methoxyphenyl) -1,3,5-triazine.

gekennzeichnet ist und unter der Handelsbezeichnung Tinosorb^® M bei der CIBA-Chemikalien GmbH erhältlich ist.An advantageous broadband filter for the purposes of the present invention is the 2,2'-methylene-bis (6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) phenol), which through the chemical structural formula

characterized and CIBA-Chemikalien GmbH available under the trade name Tinosorb M ^® in.

gekennzeichnet ist.Advantageous broadband filter according to the present invention is further the 2- (2H-benzotriazol-2-yl) -4-methyl-6- [2-methyl-3- [1,3,3,3-tetramethyl-1 - [( trimethylsilyl) oxy] disiloxanyl] propyl] phenol (CAS No .: 155633-54-8) with the INCI name Drometrizole Trisiloxane, which is represented by the chemical structural formula

is marked.

• – 3-Benzylidencampher-Derivate, vorzugsweise 3-(4-Methylbenzyliden)campher, 3-Benzylidencampher;
• – 4-Aminobenzoesäure-Derivate, vorzugsweise 4-(Dimethylamino)-benzoesäure(2-ethylhexyl)ester, 4-(Dimethylamino)benzoesäureamylester;
• – 2,4,6-Trianilino-(p-carbo-2'-ethyl-1'-hexyloxy)-1,3,5-triazin;
• – Ester der Benzaimalonsäure, vorzugsweise 4-Methoxybenzalmalonsäuredi(2-ethylhexyl)-ester;
• – Ester der Zimtsäure, vorzugsweise 4-Methoxyzimtsäure(2-ethylhexyl)ester, 4-Methoxyzimtsäureisopentylester;
• – Derivate des Benzophenons, vorzugsweise 2-Hydroxy-4-methoxybenzophenon, 2-Hydroxy-4-methoxy-4'-methylbenzophenon, 2,2'-Dihydroxy-4-methoxybenzophenon
• – sowie an Polymere gebundene UV-Filter.

The UV-B and / or broadband filters may be oil-soluble or water-soluble. Advantageous oil-soluble UV-B and / or broadband filter substances are, for. B .:

• 3-benzylidene camphor derivatives, preferably 3- (4-methylbenzylidene) camphor, 3-benzylidene camphor;
• 4-aminobenzoic acid derivatives, preferably 2-ethylhexyl 4- (dimethylamino) benzoate, 4- (dimethylamino) benzoic acid amyl ester;
• 2,4,6-trianilino (p-carbo-2'-ethyl-1'-hexyloxy) -1,3,5-triazine;
• Esters of benzaldehyde, preferably 4-methoxybenzalmalonate di (2-ethylhexyl) ester;
• Esters of cinnamic acid, preferably 4-methoxycinnamic acid (2-ethylhexyl) ester, 4-methoxycinnamic acid isopentyl ester;
• Derivatives of benzophenone, preferably 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone
• - As well as bound to polymers UV filters.

• – Salze der 2-Phenylbenzimidazol-5-sulfonsäure, wie ihr Natrium-, Kalium- oder ihr Triethanolammonium-Salz, sowie die Sulfonsäure selbst;
• – Sulfonsäure-Derivate des 3-Benzylidencamphers, wie z. B. 4-(2-Oxo-3-bornylidenmethyl)benzolsulfonsäure, 2-Methyl-5-(2-oxo-3-bornylidenmethyl)sulfonsäure und deren Salze.

Advantageous water-soluble UV-B and / or broadband filter substances are z. B .:

• Salts of 2-phenylbenzimidazole-5-sulfonic acid, such as its sodium, potassium or triethanolammonium salt, and the sulfonic acid itself;
• - Sulfonic acid derivatives of 3-Benzylidencamphers, such as. B. 4- (2-oxo-3-bomylidenemethyl) benzenesulfonic acid, 2-methyl-5- (2-oxo-3-bomylidenemethyl) sulfonic acid and salts thereof.

A further light protection filter substance according to the invention to be used advantageously is ethylhexyl-2-cyano-3,3-diphenylacrylate (octocrylene), which is under the name Uvinul ^® N 539 available from BASF and is characterized by the following structure:

It may also be of considerable advantage to use polymer-bound or polymeric UV filter substances in preparations according to the present invention, in particular those as described in US Pat WO-A-92120690 to be discribed.

Furthermore, it may be advantageous, according to the invention, to incorporate further UV-A and / or UV-B filters into cosmetic or dermatological preparations, for example certain salicylic acid derivatives such as 4-isopropylbenzyl salicylate, 2-ethylhexyl salicylate (= octylsalicylate), homomenthylsalicylate.

The list of said UV filters which can be used in the context of the present invention is of course not intended to be limiting.

The oil phase of the formulations of the invention is advantageously selected from the group of polar oils, for example from the group of lecithins and fatty acid triglycerides, namely the triglycerol esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids having a chain length of 8 to 24, in particular 12 to 18 C atoms. The fatty acid triglycerides can be selected, for example, advantageously from the group of synthetic, semi-synthetic and natural oils, such as. Cocoglyceride, olive oil, sunflower oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, castor oil, wheat germ oil, grapeseed oil, thistle oil, evening primrose oil, macadamia nut oil and the like. In the context of the present invention, further advantageous polar oil components can furthermore be selected from the group of esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids having a chain length of 3 to 30 carbon atoms and saturated and / or unsaturated, branched and / or or unbranched alcohols having a chain length of 3 to 30 carbon atoms and from the group of esters of aromatic carboxylic acids and saturated and / or unsaturated, branched and / or unbranched alcohols having a chain length of 3 to 30 carbon atoms. Such ester oils can then advantageously be selected from the group octyl palmitate, octyl cocoate, octyl isostearate, octyl dodecyl myristate, cetearyl isononanoate, isopropyl myristate, isopropyl palmitate, isopropyl stearate, isopropyl oleate, n-butyl stearate, n-hexyl laurate, n-decyl oleate, isooctyl stearate, isononyl stearate, isononyl isononanoate, 2-ethylhexyl palmitate, 2-ethylhexyl laurate, 2-hexyldecyl stearate, 2-octyl dodecyl palmitate, stearyl heptanoate, oleyl oleate, oleyl erucate, erucyl oleate, erucyl erucate, tridecyl stearate, tridecyl trimellitate, as well as synthetic, semi-synthetic and natural mixtures of such esters, e.g. B. jojoba oil.

Furthermore, the oil phase can be advantageously selected from the group of dialkyl ethers and dialkyl carbonates, advantageous z. B. dicaprylyl ether (Cetiol OE) and / or dicaprylyl, for example, that available under the trade name Cetiol CC in the company. Cognis.

It is further preferred that the oil component or components from the group Isoeikosan, Neopentylglykoldiheptanoat, propylene glycol dicaprylate / dicaprate, caprylic / capric / diglycerylsuccinate, butylene glycol dicaprylate / dicaprate, C _12-13 alkyl lactate, di-C _12-13 alkyl tartrate, triisostearin, dipentaerythrityl Hexacaprylate / hexacaprate, propylene glycol monoisostearate, tricaprylin, dimethylisosorbide. It is particularly advantageous if the oil phase of the formulations according to the invention has a content of C _12-15 -alkyl benzoate or consists entirely of this.

Advantageous oil components are also z. Butyloctyl salicylate (for example that available under the trade name Hellbrite BHB from the company CP Hall), hexadecyl benzoate and butyl octyl benzoate and mixtures thereof (Hallstar AB) and / or diethylhexylnaphthalate (Hallbrite TQ).

Any mixtures of such oil and wax components are also advantageous to use in the context of the present invention.

Furthermore, the oil phase may also advantageously contain nonpolar oils, for example those which are selected from the group of branched and unbranched hydrocarbons and waxes, in particular mineral oil, Vaseline (petrolatum), paraffin oil, squalane and squalene, polyolefins, hydrogenated polyisobutenes and isohexadecane. Among the polyolefins, polydecenes are the preferred substances.

Particularly advantageous preparations are also obtained when antioxidants are used as additives or active ingredients. According to the invention, the preparations advantageously contain one or more antioxidants. As favorable, but nevertheless optional to be used antioxidants all suitable or customary for cosmetic and / or dermatological applications or conventional antioxidants can be used.

It is also advantageous to add antioxidants to the preparations according to the invention. Advantageously, the antioxidants are selected from the group consisting of amino acids (eg glycine, histidine, tyrosine, tryptophan) and derivatives thereof, imidazoles (eg urocaninic acid) and derivatives thereof, peptides such as D, L-camosine, D- Camosin, L-carnosine and their derivatives (eg anserine), carotenoids, carotenes (eg α-carotene, β-carotene, lycopene) and their derivatives, chlorogenic acid and its derivatives, lipoic acid and derivatives thereof (eg. Dihydrolipoic acid), aurothioglucose, propylthiouracil and other thiols (e.g., thioredoxin, glutathione, cysteine, cystine, cystamine and their glycosyl, N-acetyl, methyl, ethyl, propyl, amyl, butyl and Lauryl, palmitoyl, oleyl, γ-linoleyl, cholesteryl and glyceryl esters) and their salts, dilauryl thiodipropionate, distearyl thiodipropionate, thiodipropionic acid and its derivatives (esters, ethers, peptides, lipids, nucleotides, nucleosides and salts) and sulfoximine compounds (e.g. B. buthionine sulfoximines, homocysteine sulfoximine, buthione sulfone e, penta, hexa, heptathionine sulfoximine) in very low tolerated dosages (e.g. Pmol to μmol / kg), furthermore (metal) chelators (eg α-hydroxyfatty acids, palmitic acid, phytic acid, lactoferrin), α-hydroxy acids (eg citric acid, lactic acid, malic acid), humic acid, bile acid, Bile extracts, bilirubin, biliverdin, EDTA, EGTA and their derivatives, unsaturated fatty acids and their derivatives (eg γ-linolenic acid, linoleic acid, oleic acid), folic acid and its derivatives; Ubiquinone and ubiquinol and their derivatives, vitamin C and derivatives (eg ascorbyl palmitate, Mg ascorbyl phosphate, ascorbyl acetate), tocopherols and derivatives (eg vitamin E acetate), vitamin A and derivatives (vitamin A palmitate ) and coniferyl benzoate of benzoin, rutinic acid and derivatives thereof, α-glycosylrutin, ferulic acid, furfurylidene glucitol, carnosine, butylhydroxytoluene, butylated hydroxyanisole, nordihydroguaiacetic acid, nordihydroguiaretic acid, trihydroxybutyrophenone, uric acid and its derivatives, mannose and its derivatives, zinc and its derivatives (e.g. ZnO, ZnSO ₄ ) and its derivatives (eg selenomethionine), stilbenes and their derivatives (eg stilbene oxide, trans-stilbene oxide) and the derivatives suitable for this purpose (salts, esters, ethers, sugars, nucleotides, nucleosides, Peptides and lipids) of these drugs.

Particularly advantageous for the purposes of the present invention, oil-soluble antioxidants can be used.

An amazing feature of the present invention is that formulations of the present invention are very good vehicles for cosmetic or dermatological agents into the skin, with preferred agents being antioxidants which can protect the skin from oxidative stress. Preferred antioxidants are vitamin E and its derivatives as well as vitamin A and its derivatives.

The amount of the antioxidants (one or more compounds) in the preparations is preferably from 0.001 to 30% by weight, particularly preferably from 0.05 to 20% by weight, in particular from 1 to 10% by weight, based on the total weight of the preparation ,

If vitamin E and / or its derivatives represent the antioxidant (s), it is advantageous to choose their respective concentrations from the range of 0.001-10% by weight, based on the total weight of the formulation.

If vitamin A or vitamin A derivatives, or carotenes or derivatives thereof, are the antioxidant (s), it is advantageous if their respective concentrations are in the range from 0.001-10% by weight, based on the total weight of the formulation, of to choose.

Powders are composed of one or more powder bases, more or less finely divided, powdery preparations, which, according to their intended use, one or more active ingredients, preservatives, perfume oils, dyes, etc. may be added. The FDA's OTC Miscellaneous External Panel has defined the following for powders: A homogeneous dispersion of finely divided, relatively dry, finely divided material consisting of one or more substances "(FDC Reports [Pink Sheet] 41, No. 33, T & G-4 [Aug. 13, 1979]).

The composition of a powder largely depends on the tasks it has to fulfill. But powders can also be diluents for medicines, eg. As antibiotics, sulfonamides, etc., be. Liquid powders are usually from talc, zinc oxide and / or titanium dioxide, glycerol and water thick preparations (shaking mixtures). Compact powders are briquetted by high pressure or sintered together by the addition of calcium sulfate (gypsum) powder bases. In addition, powders are also provided and used in aerosol form after it has been possible to develop valves that largely eliminate the possibility of obstruction of the valve ports. The always to be feared sedimentation of the incorporated powder particles can also be prevented by incorporating into the formulation suitable suspending or suspending aids, for example, alkali metal, ammonium or amine salts of a dialkylsulfosuccinate with alkyl groups of 4-12 carbon atoms, eg. Sodium dioctylsulfosuccinate (typically about 0.002-0.015 weight percent), or an alkylbenzenesulfonic acid having alkyl groups of 8-14 C-atoms, e.g. For example, sodium dodecylbenzenesulfonate.

The following examples are intended to illustrate the present invention without limiting it. The numerical values in the examples are percentages by weight, based on the total weight of the respective preparations. By "aminobenzophenone" is meant in the examples of 2- (4 '- (diethylamino) -2'-hydroxybenzoyl) -benzoesäurhexylester to understand.

Examples

1. O / W emulsions 1 2 Glycerol monostearate SE 1.00 Glyceryl stearate citrate 2.00 stearic acid 3.00 PEG-40 Stearates 2.00 Cetyl phosphates 1.00 Stearyl alcohol Cetyl alcohol 1.00 Vinyldimethicone / Methicon Silesquioxane Crosspolymer (KSP-100, Shin-Etsu) 7.50 2.50 aminobenzophenone 2.00 3.00 Methylene bis-benzotriazolyl tetramethylbutylphenol 0.50 3.00 Bis-ethylhexyloxyphenol Methoxypheny triazine 1.50 Butyl methoxydibenzoylmethane Diethylhexyl butamidotriazone 2.00 Ethylhexyl triazone 4.00 Parsol SLX ^® 4-methylbenzylidene camphor 2.00 Benzophenone-3 Mexoryl ^® SX Mexoryl ^® XL 4.00 1.00 Ethylhexyl methoxycinnamate 6.00 octocrylene 4.00 Phenyl dibenzimidazole tetrasulfonic acid 3.00 Phenylbenzimidazole sulfonic acid Titanium dioxide MT-100 TV 1.50 Z- ^Cote® HP1 5.00 C12-15 alkyl benzoates 2.50 4.00 Dicaprylyl ether 2.00 Butylene glycol dicaprylate / dicaprate Dicaprylyl carbonate dimethicone 0.50 2.00 cyclomethicone Shea butter 2.00 PVP hexadecene copolymer glycerin 7.50 5.00 Xanthan gum Sodium carbomer 0.20 Vitamin E acetate 0.75 ascorbyl 0.15 Alpha-glucosyl 0.15 2,6 diethylhexylnaphthalate Hexadecyl / butyloctylbenzoate Trisodium EDTA 0.50 methylparaben 0.50 phenoxyethanol 0.40 0.50 ethanol 2.00 3.00 Perfume 0.20 water ad. 100 ad. 100 2. Hydrodispersions 1 Ceteareth-20 1.00 Cetyl alcohol Sodium carbomer Acrylates / C10-30 Alkyl Acrylate Crosspolymer Xanthan gum 0.50 Vinyldimethicone / Methicon Silesquioxane Crosspolymer (KSP-104, Shin-Etsu) 2.50 aminobenzophenone 3.00 Ethylhexyl methoxycinnamate Bis-ethylhexyloxyphenol Methoxypheny triazine Butyl methoxydibenzoylmethane 1.00 Diethylhexyl butamidotriazone Methylene bis-benzotriazolyl tetramethylbutylphenol 3.00 Ethylhexyl triazone 4.00 octocrylene Phenyl dibenzimidazole tetra-sulfonic acid 1.00 Mexoryl ^® SX Mexoryl ^® XL 3.00 Phenylbenzimidazole sulfonic acid 0.50 Titanium dioxide T805 ^® 0.50 Z- ^Cote® 2.00 C12-15 alkyl benzoates 2.00 Butylene glycol dicaprylate / dicaprate 4.00 Dicaprylyl carbonate dimethicone cyclomethicone 10.00 Shea butter PVP hexadecene copolymer 0.50 Ethylhexyloxyglycerin glycerin 3.00 Butylene glycol Glycine soy Vitamin E acetate 0.50 α-glycosyl rutin butyloctylsalicylate 2,6 diethylhexylnaphthalate Trisodium EDTA Concubes LMB ^® 0.20 methylparaben 0.50 phenoxyethanol 0.50 ethanol 3.00 Perfume 0.20 Dyes, water-soluble water ad 100

Claims (12)

Cosmetic and / or dermatological composition for protection against UV radiation with 2,2'-methylenebis (6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) -phenol ) and coated powders consisting of a core of at least one siloxane elastomer selected from the group of siloxane elastomers either by reaction of vinyl-terminated polymethylsiloxane and methylhydrodimethylsiloxane or by reaction of hydroxy-terminated dimethylpolysiloxane and trimethylsiloxy-terminated methylpolysiloxane, the coating consisting of a trimethylsiloxysilicate and / or its derivative containing silicon-bonded fluoroalkyl and / or phenyl groups, characterized in that the coated powders used are vinyl dimethicone / methicone silesquioxane crosspolymers, and from 1 to 4% by weight of 2- (2H-benzotriazol-2-yl) -4-methyl-6- [2-methyl-3- [1,3 , 3,3-tetramethyl-1 - [(tri-methylsilyl) oxy] disiloxanyl] -propyl] -phenol, 0.5 to 5.25% by weight of 2,2'-methylene-bis (6- (2H -benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) -phenol), the sum concentration of 2- (2H-benzotriazol-2-yl) -4-methyl-6- [2 -methyl-3- [1,3,3,3-tetramethyl-1 - [(trimethylsilyl) oxy] disiloxanyl] propyl] phenol and 2,2'-methylene-bis (6- (2H-benzotriazole-2 -yl) -4- (1,1,3,3-tetramethylbutyl) phenol) 6% by weight and the siloxane elastomer is present in proportions of 0.5 to 12% by weight. Preparation according to at least one of the preceding claims, characterized in that the particles of the coated powders have a particle size distribution of 0.7 to 30 microns and an average particle size of 2 to 30 microns and a powder hardness of 30 to 75. Preparation according to at least one of the preceding claims, characterized in that the coated powders are used in combination with oils of hydrocarbons of animal and / or vegetable origin, synthetic oils, synthetic esters, synthetic ethers or mixtures thereof. A preparation as claimed in at least one of the preceding claims, characterized in that the coated powders are used in combination with unbranched silicone oils or cyclic silicone oils or mixtures thereof which are liquid or pasty at room temperature. Preparation according to at least one of the preceding claims, characterized in that the content of one or more benzotriazoles from the range 0.1 to 20 wt .-%, advantageously 0.1 to 15 wt .-%, most preferably 0.1 to 10 % By weight is selected. A preparation as claimed in at least one of the preceding claims, characterized in that it contains at least one further UV filter substance selected from the group consisting of triazines, aminobenzophenones, the UV filter which is liquid at room temperature, sulfonated, water-soluble UV filters, oil-soluble UV rub-through filters and organic and organic UV filters or inorganic pigments, which are preferably treated on the surface. Preparation according to at least one of the preceding claims, characterized in that additional inorganic micropigments are included. Preparation according to at least one of the preceding claims, characterized in that metal oxides having an average particle size of 10 to 100 nm are used as the inorganic micropigment. A preparation according to at least one of the preceding claims, characterized in that oxides of titanium, iron, zinc, zirconium or cerium are used as inorganic micropigments. Preparation according to at least one of the preceding claims, characterized in that metal oxides coated as inorganic micropigments are used. Preparation according to at least one of the preceding claims, characterized in that the inorganic micropigments are present in a proportion of 0.5 to 30 wt .-%. Use of a preparation according to at least one of the preceding claims for protecting the skin or the hair from UV light, damage caused by UV light and aging phenomena caused by UV light.