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Publication date
Application filed by Zentiva, K.S.filedCriticalZentiva, K.S.
Priority to CZ2015-914ApriorityCriticalpatent/CZ2015914A3/en
Priority to EP16822881.5Aprioritypatent/EP3380083A1/en
Priority to PCT/CZ2016/000124prioritypatent/WO2017088841A1/en
Publication of CZ2015914A3publicationCriticalpatent/CZ2015914A3/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Řešení popisuje způsob přípravy apixabanu v amorfní formě pomocí metody enkapsulace do porézního nosiče. Takto připravený apixaban lze použít pro léčení nebo prevencí tromboembolických příhod. Součástí řešení je také farmaceutická kompozice obsahující apixaban připravený metodou enkapsulace do porézního nosiče.The present invention relates to a process for preparing apixaban in amorphous form by means of an encapsulating method into a porous support. Apixaban thus prepared can be used to treat or prevent thromboembolic events. Also included is a pharmaceutical composition comprising apixaban prepared by encapsulation into a porous carrier.
CZ2015-914A2015-11-262015-12-18Preparation of a dosage form containing amorphous apixaban enclosed in a porous carrier
CZ2015914A3
(en)