CZ2015914A3 - Preparation of a dosage form containing amorphous apixaban enclosed in a porous carrier - Google Patents

Preparation of a dosage form containing amorphous apixaban enclosed in a porous carrier Download PDF

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Publication number
CZ2015914A3
CZ2015914A3 CZ2015-914A CZ2015914A CZ2015914A3 CZ 2015914 A3 CZ2015914 A3 CZ 2015914A3 CZ 2015914 A CZ2015914 A CZ 2015914A CZ 2015914 A3 CZ2015914 A3 CZ 2015914A3
Authority
CZ
Czechia
Prior art keywords
porous carrier
enclosed
preparation
apixaban
dosage form
Prior art date
Application number
CZ2015-914A
Other languages
Czech (cs)
Inventor
Pavel Kovačík
Katarína Púchla
Pavel Žvátora
Ondřej Dammer
Lukáš Krejčík
Josef Beránek
Original Assignee
Zentiva, K.S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentiva, K.S. filed Critical Zentiva, K.S.
Priority to CZ2015-914A priority Critical patent/CZ2015914A3/en
Priority to EP16822881.5A priority patent/EP3380083A1/en
Priority to PCT/CZ2016/000124 priority patent/WO2017088841A1/en
Publication of CZ2015914A3 publication Critical patent/CZ2015914A3/en

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  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Řešení popisuje způsob přípravy apixabanu v amorfní formě pomocí metody enkapsulace do porézního nosiče. Takto připravený apixaban lze použít pro léčení nebo prevencí tromboembolických příhod. Součástí řešení je také farmaceutická kompozice obsahující apixaban připravený metodou enkapsulace do porézního nosiče.The present invention relates to a process for preparing apixaban in amorphous form by means of an encapsulating method into a porous support. Apixaban thus prepared can be used to treat or prevent thromboembolic events. Also included is a pharmaceutical composition comprising apixaban prepared by encapsulation into a porous carrier.

CZ2015-914A 2015-11-26 2015-12-18 Preparation of a dosage form containing amorphous apixaban enclosed in a porous carrier CZ2015914A3 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CZ2015-914A CZ2015914A3 (en) 2015-12-18 2015-12-18 Preparation of a dosage form containing amorphous apixaban enclosed in a porous carrier
EP16822881.5A EP3380083A1 (en) 2015-11-26 2016-11-21 Preparation of a drug form containing amorphous apixaban
PCT/CZ2016/000124 WO2017088841A1 (en) 2015-11-26 2016-11-21 Preparation of a drug form containing amorphous apixaban

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CZ2015-914A CZ2015914A3 (en) 2015-12-18 2015-12-18 Preparation of a dosage form containing amorphous apixaban enclosed in a porous carrier

Publications (1)

Publication Number Publication Date
CZ2015914A3 true CZ2015914A3 (en) 2017-06-28

Family

ID=59249217

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ2015-914A CZ2015914A3 (en) 2015-11-26 2015-12-18 Preparation of a dosage form containing amorphous apixaban enclosed in a porous carrier

Country Status (1)

Country Link
CZ (1) CZ2015914A3 (en)

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