CZ137499A3 - Mixture for preparing detergents - Google Patents

Abstract

Compositions for making detergents in the form of cubes in which polyalkylene glycols with quite specific molecular moieties are used weight. These means are pleasant, well foamed and provide Sensory profiles required by customers. To achieve these a significant amount must be added to the washing bar of these specific polyethylene glycols. For processing these the composition in the form of cubes is a preferred melt casting method.

Description

Mixture for the production of detergents

Technical field

The present invention relates to skin cleansing bars which are preferably produced by the melt casting method. These cubes are extremely fine, well foaming and provide the sensory qualities demanded by customers.

BACKGROUND OF THE INVENTION

Body wash cubes are increasingly directed to finer compositions that provide improved skin care, for example by minimizing skin irritation and enhancing the moisturizing effect. It is advantageous to manufacture soap bar formulations that provide a significant amount of emollient oil which provides a large number of customers with positive sensory sensations. For the proper processing of such cube formulations, the melt casting method is preferably used.

Therefore, an economically advantageous chemical that can act as a filler / binder of a cube, which enhances the softness of the skin or moisturizes it, enhances the bar's soap and allows cube processing, is still being sought. Effective bar structurants are, for example, solid polyalkylene glycols (e.g. polyethylene glycols (PEG) with a molecular weight of more than 2000), which also do not have antifoam properties. However, compared to lower molecular weight PEG, they provide a much lower oily skin feel, which indicates wetting for many customers, and less easily mixed with long chain fatty acid soaps used as gelling agents in the present invention. Solid fatty acids, on the other hand, can function as effective cube structurants, but tend to foam.

• · · · · · · · · · · · · · · · ·

- 2 When paraffin waxes are added to the bar in relatively high amounts (ie more than 25% by weight of the total composition), they have antifoaming effects, especially in the presence of hydrophobic emollient oils.

In the present invention, Applicants have used a relatively high content of low molecular weight polyalkylene glycols (e.g., polyethylene glycol having a molecular weight of 300 to 1500) in a synthetic melt-casting detergent bar. In vivo and in vitro data have shown that these low molecular weight PEGs can significantly lessen the irritability of commonly used anionic surfactants only at their very high content (by weight ratio of polyethylene glycol to anionic surfactant of 1: 1 and higher). Unlike solid PEGs with a molecular weight of more than 2000, low molecular weight PEGs are more readily miscible with long-chain fatty acid soaps, which are gelling agents within the scope of the present invention, and are therefore an important component of the immobilized liquid fraction of these bars. It is this liquid fraction that dissolves readily in use, with the beneficial effects of improved skin feel, softness and soap. In addition, low molecular weight PEGs further improve the desirable soap properties of the skin cleansing composition.

Using high contents of these relatively low molecular weight materials, Applicants were able to obtain cubes which at the same time (1) provided the desired user and processing properties, (2) foamed well, and (3) were less irritating.

The use of polyalkylene glycols (e.g. polyethylene glycol) in body wash compositions is not in itself new.

U.S. Pat. No. 3,312,627 (D. Hooker) discloses, for example, a bar formulation comprising 30 to 70% by weight polyethylene glycol (PEG) as a bar structurant for a nonionic formulation that is substantially free of anionic detergents. PEG φφ · φφ · Φ ·· ··

The 3 used in the present invention has a molecular weight of more than 4000 Daltons, which is substantially more than the molecular weight claimed for the PEG used in the present invention (<1500). In contrast to the present invention, the aforementioned patent used a substantially higher amount of high molecular weight PEG per total bar composition. In addition, the PEG / anionic surfactant ratio is not important in this patent as it primarily relates to nonionic formulations.

International patent application no. 93/07245 (F. Moran, B. O'Briain and D. Moran, NEPHIN) discloses dice shampoo compositions containing 12 to 20% by weight of synthetic detergents and 70 to 80% by weight of PEG with molecular weights between 5000 and 10 One embodiment of the present invention comprises a softening PEG having a molecular weight of between 100 and 800 (preferably 1-8% by weight of the total composition). In contrast to the present invention, said patent application used a significant amount (70-80% by weight) of high molecular weight PEG in the mixture for the bars as a whole. The patent used substantially smaller amounts of low molecular weight PEG than used in the present invention.

Simultaneous application WO 94/21778, corresponding to U.S. Pat. No. 08 / 594,363, which is a continuation of U.S. Pat. No. 08 / 213,283, entitled "Synthetic Detergent Bar and Manufacture Thereof," by J. Chambers et al., Discloses a bar comprising 10 to 60% by weight of synthetic surfactants and 10 to 60% by weight of PEG as a structuring agent. The PEG used has a melting range between 40 ° C and 100 ° C and a molecular weight range between 1500 and 10,000. This molecular weight makes the PEG solid at room temperature. The PEG molecular weight used is higher than claimed in the present invention (&lt; 1500). Also, the present patent application does not disclose a PEG / anionic ratio of at least φ φ φ

1: 1, which corresponds to an increase in fineness which is critical to the present invention.

U.S. Pat. No. 5,520,840 (M. Massaro et al.) Discloses skin cleansing bars containing 10 to 60% by weight of a synthetic surfactant, 10 to 60% by weight of a water-soluble structurant (e.g. PEG) with a melting range between 40 ° C and 100 ° C and 1 to 25% by weight of a water-soluble starch such as maltodextrin. The molecular weight of the PEGs used (> 1500) is higher than claimed in the present invention. The patent application also does not disclose a PEG / anionic ratio of at least 1: 1 which corresponds to an increase in fineness which is critical to the present invention.

U.S. Pat. No. 2,287,484 to Lundberg discloses a closed-die die comprising 35 to 70% by weight of an anionic synthetic surfactant and 22 to 50% by weight of a fatty acid. The bar may also contain up to 10% by weight of ethylene and diethylene glycols as additives. As found with the present invention, ethylene and diethylene glycols are not as effective as low molecular weight PEG (molecular weight greater than 300) in reducing skin irritation by anionic surfactants. Also, the disclosed patent does not disclose by weight a PEG / anionic surfactant ratio of at least 1: 1, which corresponds to an increase in fineness which is critical to the present invention.

Co-pending Applicants WO 97/47722, corresponding to U.S. Pat. No. 08 / 662,394, filed June 12, 1996, discloses a fine bar formulation comprising 10 to 60% by weight of synthetic surfactants, 10 to 50% by weight of high molecular weight PEG having a melting point greater than 40 ° C and 0.1 to 10% by weight. low molecular weight PEG (melting point less than 40 ° C) as a processing aid. The application claims the use of low-molecular-weight PEG in relatively small-sized PEGs. · ··· · · ··· ·· ♦ · * · · · ·

- 5 amounts as lubricant to facilitate the extrusion process. This differs substantially from the present invention, which uses relatively high contents of low molecular weight PEG (e.g., > 10% by weight of the total composition) in the bar as a wetting agent. Also, the present patent application did not specify a PEG / anionic surfactant weight ratio that is critical to the present invention to achieve excellent skin softness.

U.S. Pat. Nos. 5,262,079 and 5,227,086 (M. Kacher, J. Taner, D. Quiriam, D. Schmidt and M. Evans) disclose molded bar form cleaners containing 5 to 50% by weight of a mixture of free and neutralized monocarboxylic acid, 15 to 65% by weight of a synthetic anionic nonionic bar refinement composition and 15 to 55% by weight of water. The bar refinement aid consists of 5 to 50% by weight of synthetic surfactants and 0 to 40% by weight of polyethylene glycol or polypropylene glycol having a molecular weight of from about 44 to 10,000 Daltons. Said patents do not disclose or suggest the use of polyethylene glycols having a molecular weight between 400 and 1500 with specific PEG / anionic surfactant weight ratios to achieve both improved melt castability and fineness. In addition, in order to achieve the desired user properties of the bar (e.g., slurry and hardness), the present inventors use the addition of only 2-10% by weight of water to the claimed cube formulations, which is substantially less than 15-55% by weight of water claimed in said patents.

Finally, the applicants have filed WO 98/16619, which corresponds to U.S. Pat. 08/733 036, entitled "Pourable Cast Melt Bar Compositions Comprising Low Levels Of Water And Minimum Ratios Of Polyol To Water". The present invention is made by the same melt casting method. However, the mention of the application is not

- 6 directed to specific compositions in which high polyalkylene glycol contents with a molecular weight between 400 and 1500 and a ratio of polyalkylene glycol to anionic surfactant of at least 1: 1 are used.

• · ·

• 9 9 · 9

SUMMARY OF THE INVENTION

The present invention relates to cube formulations using alkylene glycols (e.g. polyethylene glycols) with a very specific molecular weight range (high enough molecular weight to reduce the roughness of anionic surfactants but low enough molecular weight to obtain the desired sensory profile and allow processing by melt casting) and the ratio of alkylene glycol to anionic surfactants is maintained at least 1: 1 and higher. These compositions are gentle, well foaming and provide the sensory profiles desired by customers.

More particularly, the invention includes:

(1) 2 to 35%, preferably 10 to 30% by weight of the total synthetic anionic surfactant composition;

(2) 0 to 20% by weight of the total surfactant composition selected from the group of amphoteric, zwitterionic, nonionic and mixtures thereof; the amphoteric and zwitterionic surfactants preferably comprise 2-15% by weight of the total composition;

(3) 10 to 70% by weight of the total composition of a polyalkylene glycol or a mixture of polyalkylene glycols having a molecular weight of greater than 300 to about 1500 Daltons;

• 9 · 9 9 9 9

9,999,999 9,999,999

9 9 9 9 9 9

9 99 99 99

7 wherein the weight ratio of polyalkylene glycol to anionic surfactant is at least 1: 1, preferably 2: 1 and higher;

(4) about 0 to 35% by weight of the total solid composition of the present invention to provide the desired structure and fillers selected from (i) polyalkylene glycols having a molecular weight of 2500 to 10,000 and a melting point of about 55 to 65 ° C; (ii) C ₈ to C 24 free fatty acids, preferably straight chain and preferably saturated; (iii) a C ₈ to C ₂ alkanol, preferably straight chain and preferably saturated;

(iv) water-soluble starches (for example maltodextrin);

(5) about 1 to 20% by weight of the total gelling agent composition; and (6) about 2 to 10% by weight of the total water composition.

DETAILED DESCRIPTION OF THE INVENTION

The present invention relates to compositions in which alkylene glycols with a very specific molecular weight range (sufficiently high molecular weight to attenuate the roughness of anionic surfactants but sufficiently low molecular weight to obtain the desired sensory profile and to allow melt casting) are used. alkylene glycol to anionic surfactants to provide compositions that are (1) delicate, (2) maintain a good foaming profile, and (3) provide both the sensory profiles desired by customers (i.e., due to lower molecular weight) and advantageous processing properties .

·· · ·· ·· ·· ··

More specifically, the invention includes:

(1) 2 to 35%, preferably 10 to 30% by weight of the total synthetic anionic surfactant composition;

(2) 0 to 20% by weight of the total surfactant composition selected from the group of amphoteric, zwitterionic, nonionic and mixtures thereof; the amphoteric and zwitterionic surfactants comprise 2-15% by weight of the total composition;

(3) 10 to 70% by weight of the total composition of a polyalkylene glycol or a mixture of polyalkylene glycols having a molecular weight of greater than 300 to about 1500 Daltons;

wherein the weight ratio of polyalkylene glycol to anionic surfactant is at least 1: 1, preferably 2: 1 and higher;

(4) about 0 to 35% by weight of the total solid composition of the present invention to provide the desired structure and fillers selected from (i) polyalkylene glycols having a molecular weight of 2500 to 10,000 and a melting point of about 55 to 65 ° C; (ii) C ₈ to C ₂₄ free fatty acids, preferably straight chain and preferably saturated; (iii) C ₈ to C ₂ alkanols, preferably straight chain and preferably saturated; (iv) water-soluble starches (for example maltodextrin);

(5) further, since a large amount of low molecular weight polyalkylene glycol is in the form of a liquid or paste, about 1 to 20% by weight of the total gelling agent composition, as described in more detail below, to improve the integrity of the bar; and • 4 4 4 4 9 4 4 • 449 9 9 4 4

4 4 4 4 4 4 9

4,9444,444,444

- 9 (6) about 2 to 10% by weight of the total water composition.

4 44 9

Synthetic non-soap surfactant

The surfactant system of the invention will generally comprise at least one anionic surfactant as well as an optional second surfactant selected from the group of amphoteric / zwitterionic surfactants, nonionic surfactants or mixtures thereof. Preferably, the composition comprises an anionic surfactant or anionic surfactant and an amphoteric / zwitterionic surfactant.

The anionic surfactant which may be used may be from aliphatic sulfonate, such as a primary alkane (e.g., _{C8-C 2} 2) sulfonate, primary alkane (e.g., _C8 -C22) disulfonate, _C8 -C22alkensulfonát, _C8 -C ₂ hydroxyalkane sulfonate or alkyl glyceryl ether sulfonate (AGS); or aromatic sulfonates such as alkylbenzenesulfonate.

The anionic surfactant may be, for example, an alkyl sulfate (e.g., a C 12 -C ₁₈ alkyl sulfate) or an alkyl ether sulfate (including alkyl glyceryl ether sulfates). Alkyl ether sulfates include compounds of the formula:

RO (CH ₂ CH ₂ O) _n SO ₃ M wherein R is alkyl or alkenyl of 8 to 18 carbon atoms, preferably 12 to 18 carbon atoms, n has an average value greater than 1.0, preferably greater than 3; and M is a solubilizing cation such as sodium, potassium, ammonium or substituted ammonium. Ammonium and sodium lauryl ether sulfates are preferred.

• «# ·· · ·· · ♦« «· * ·.

The anionic surfactant may also be from the group of alkyl sulfosuccinates (including mono- and dialkyl, for example, C ₆ C ₂ sulfosuccinates); alkyl and acyl taurates, alkyl and acyl sarcosinates, sulfoacetates, C ₈ -C ₂₂ alkyl phosphates and phosphates, alkyl phosphate esters and alkoxylalkyl phosphate esters, acyl lactates, C ₈ C ₂ monoalkyl succinates and maleates, sulfoacetates, alkyl glucosides and acyl isethionates.

The sulfosuccinates may be monoalkylsulfosuccinates of the formula

R ¹ O ₂ CH ₂ CH (SO ₃ M) CO2M; and amide-MEA sulfosuccinates of the formula

R ¹ CONHCH ₂ CH ₂ O ₂ CCH ₂ CH (SO ₃ M) CO ₂ M wherein R ¹ is C ₈ -C ₂₂ alkyl and M is a solubilizing cation. Sarcosinates are generally designated by the formula

RCON (CH ₃ ) CH ₂ CO ₂ M, wherein R is C ₈ -C ₂ alkyl and M is a solubilizing cation. Taurates have a general formula

R ² CONR ³ CH ₂ CH ₂ SO ₃ M wherein R ² is C 8 -C 20 alkyl, R ³ is C 1 -C ₄ alkyl, and M is a solubilizing cation.

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C ₈ -C ₁₈ acyl isethionates are particularly preferred. These esters are produced by reaction between an alkali metal isethionate with mixed aliphatic fatty acids of 6 to 18 carbon atoms and an iodine number of less than 20. At least 75% by weight of the mixed fatty acids has from 12 to 18 carbon atoms and up to 25% by weight has from 6 up to 10 carbon atoms.

Acyl isethionates, if present, will generally comprise from about 10% to about 35% by weight of the total bar composition. Preferably, the component will be present at a concentration of from about 10 to about 30% by weight.

The acylisethionate may be an alkoxylated isethionate as described in Llardi et al., U.S. Pat. 5, 393, 466, which is hereby incorporated by reference. This compound has the general formula

O X Y

II I I

R - C - O - CH - CH ₂ - (OCH - CH ₂ ) m -SO ₃ M ⁺ wherein R is an alkyl group of 8 to 18 carbon atoms, m is an integer from 1 to 4, X and Y are hydrogen or an alkyl group having 1 to 4 carbon atoms and M ⁺ is a monovalent cation such as sodium, potassium or ammonium.

The anionic component will generally comprise from about 2 to 35% by weight of the bar, preferably 10 to 30% by weight.

The amphoteric surfactants that may be used in the present invention contain at least one acid group. This may be a carboxylic or sulfonic acid group. Contain quart! nitrogen atom and therefore are quaternary amido acids. In general, they should contain an alkyl or alkenyl group of 7 to 18 carbon atoms. They will usually comply with the overall structural formula:

• · · · · · · · · · · · · · · · ·

- 12 R ²

R ¹ - [- C - NH - (CH ₂ ) _n -] _{m -} N ^{+ -} x - y

R ³ wherein R ¹ is C 7 -C 18 alkyl or alkenyl;

R ² and R ³ are each independently alkyl, hydroxyalkyl or carboxyalkyl of 1 to 3 carbon atoms; n is 2 to 4;

m is 0 to 1;

x is C 1 -C 3 alkylene, optionally substituted with a hydroxyl group, and y is -CO ₂ - or -SO ₃ -

Suitable amphoteric detergents within the above general formula include simple betaines of the formula:

R ²

R ¹ —N ⁺ —CH ₂ CO ₂ · and amidobetaines of formula:

R ²

R ¹ -CONH (CH 2) m -N ⁺ CH ₂ CO ₂ 'wherein m is 2 or 3.

• • •

In both formulas, R ^{1 is} C 7 -C 18 alkyl or alkenyl; and R ² and R ³ are independently alkyl, hydroxyalkyl or carboxyalkyl of 1 to 3 carbon atoms. R ¹ may in particular be a mixture of C ₁₂ and C 14 alkyl groups derived from coconut oil, so that at least half, preferably at least three quarters of the groups R ¹ have 10 to 14 carbon atoms. R ² and R ³ are preferably methyl.

Another possibility is that the amphoteric detergent is a sulfobetaine of formula

R ²

R ¹ = N ⁺ - (CH ₂ ) ₃ SO ₃ 'or

R ²

R ^{1 -} CONH (CH 2) m - N ⁺ - (CH 2) ₃ SO ₃ 'wherein m is 2 or 3, or variants thereof in which the (CH ₂ ) ₃ SO ₃ ' group is replaced by

OH

I —CH ₂ CHCH ₂ SO ₃ ·

In these formulas, R ¹ , R ^2, and R ^{3 are} as discussed for amidobetaine.

Amphoteric surfactants, if present, generally comprise 2 to 15% by weight of the bar.

• 0 0 · 0 0 0 ·· 0 000 000 0 ·· · 0 0 ·· 0 · 0 00 00 00 00

Other surfactants (i.e., non-ionic or cationic) may also optionally be used, but these should generally not comprise more than 0.01 to 10% by weight of the bar.

Nonionic surfactants are in particular the reaction products of compounds having a hydrophobic group and a reactive hydrogen atom, for example aliphatic alcohols, acids, amides or alkylphenols with alkylene oxides, in particular ethylene oxide either alone or together with propylene oxide. Specific nonionic detergent compounds are condensates of ethylene oxide with alkyl (C ₆ -C ₂ 2) phenols, Io condensation products of aliphatic (C ₈ -C ₁₈₎ primary or secondary linear or branched alcohols with ethylene oxide, and products made by condensation of ethylene oxide with the reaction products of ethylene oxide and ethylenediamine . Other so-called nonionic detergent compounds include long-chain tertiary amine oxides, long-chain tertiary phosphine oxides and dialkyl sulfoxides.

Nonionic surfactants can also be sugar amides, such as polysaccharide amides. In particular, the surfactant may be one of the lactobionamides described in U.S. Pat. No. 5,389,279 (Au et al.), Which is incorporated herein by reference, and polyhydroxyamides as described in U.S. Pat. No. 5,312,954 (Letton et al.), Which is incorporated herein by reference.

Examples of cationic surfactants are quaternary ammonium compounds such as alkyldimethylammonium halides.

Other surfactants that may be used are described in U.S. Pat. 3,723,325 (Parran Jr.) and &quot; Surface Active Agents and Detergents! (Parts I and II), Schwartz, Perry & Berch, both of which are also incorporated herein by reference.

• · · ·

- 15 Polyalkylene glycol

A second necessary component of the invention is a polyalkylene glycol or a mixture of polyalkylene glycols, wherein the polyalkylene glycol is, for example, polyethylene or polypropylene glycol. The polyalkylene glycols must have a molecular weight between more than 300, preferably more than about 350, and 1500 Daltons. This molecular weight range is important because, at a molecular weight below the minimum value of 300, PEG in cubes does not significantly reduce skin irritation caused by anionic surfactants (see Example 2, Figures 2 and 3); and at molecular weights above 1500, the PEG molecule is not readily miscible with long chain fatty acid soaps that are used as gelling agents. Also, at molecular weights above 1500, PEG does not provide as oily skin feel as lower molecular weight PEG.

Another important aspect of the invention is that the weight ratio of alkylene glycol to anionic surfactants is at least 1: 1 and preferably 2: 1 and higher. Again, at a weight ratio of less than 1: 1, fineness cannot be easily felt (see Example 1, Fig. 1).

Generally, this component of the compound mixture will comprise from about 10% to about 70% by weight of the bar formulations.

Gelling agent

The compositions of the invention require the presence of a gelling agent. Without wishing to be bound by theory, it is believed that this component is necessary because the higher low molecular weight polyalkylene glycols required to carry out the invention provide the product in the form of a liquid or paste. It is believed that a gelling agent is necessary to improve the integrity of the bar.

Examples of gelling agents include, but are not limited to:

· · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · ·

(I) a neutralized C ₈ to C ₂₅ carboxylic acid (soap), preferably a neutralized C ₈ to C ₂₅ monocarboxylic acid (straight chain, saturated soap);

(ii) paraffin waxes, polyethylene waxes, petroleum jelly, fats, jellies, colloidal silicon dioxide and / or aluminosilicates, urea and clay.

Examples of waxes that can be used include Paraffin Wax from Whittaker, Clark & Daniels, Inc. and Luwax of BASF a

MULTIWAX Microcrystalline WAX by Witco. A preferred wax is glyceryl stearate.

The gelling agent will generally comprise 1 to 20% by weight of the total composition.

Moisture content in cubes

The bars of the invention use a low water content, ie 2% to less than 10% by weight, preferably 2% to 8%, more preferably 3% to 7% by weight of the total composition. The water contents are expediently kept within a range to obtain a homogeneous pumpable melt which upon cooling forms resistant solids. Excess water leads to poor mixing, low viscosities and phase separation in the melt and an unacceptably soft solid, and cooling lubricity.

Structures and fillers, if applicable

Another optional component of the invention are solids to assist in forming the desired structure and filler, which are used to maintain the structural integrity of the bar. Examples of such structurants are, without limitation, the following;

polyalkylene glycols having a molecular weight of 2500 to 10,000 and a melting point of about 40 ° C to 65 ° C; C ₈ to C ₂ alkanols, preferably straight chain, preferably saturated C ₄ to C ₁₈ alkanols; C ₈ to

C 25 fatty acids, preferably straight chain, preferably saturated C _1-4 to C 22 fatty acids; and water-soluble starches such as maltodextrin.

9 9 9999 9999 9 9 9 9 99 99

9 · ··· · · · · · · · · · · ·

The fabric builder and filler are generally 0 to 35% by weight of the bar, preferably 10 to 25% by weight.

Other optional components present

Other components that can be used in the bars of the invention are as follows:

The bars according to the invention also generally contain 0 to 30% by weight, preferably 1 to 25% by weight, of the beneficial agent in the bar material.

The beneficial agent of the present invention may be a single component of the beneficial agent or may be a beneficial agent added via a carrier. Another beneficial agent may be a mixture of two or more compounds, one or all of which may have beneficial effects. In addition, the beneficial agent itself may serve as a carrier for other components that need to be added to the bar material.

A beneficial agent may be an "emollient oil" meaning a skin softener (stratum corneum) by increasing the water content in it and maintaining softness by slowing down the decrease in water content.

Preferred emollients include:

(a) silicone oils, gums, and modifications thereof such as straight and cyclic polydimethylsiloxanes; amino-, alkyl-, alkylaryla-arylsilicone oils;

(b) fats and oils, including natural fats and oils such as jojoba oil, soybean oil, rice bran oil, avocado oil,

- 18 olive oil, almond oil, sesame oil, peach oil, castor oil, coconut oil, mink oil; cocoa fat, beef tallow, lard; hardened oils obtained by hydrogenation of the above oils; and synthetic mono-, di- and triglycerides such as myristic acid glyceride and 2-ethylhexanoic acid glyceride;

(c) waxes such as carnauba, spermaceti, bees, lanolin and derivatives thereof;

(d) hydrophobic plant extracts;

(e) hydrocarbons such as liquid paraffins, petrolatum, microcrystalline wax, ceresin, squalene, landing and mineral oil;

(f) higher fatty acids such as lauric, myristic, palmitic, stearic, behenic, oleic, linoleic, linolenic, lanolic, isostearic and polyunsaturated fatty acids (PUFA);

(g) higher alcohols such as lauryl, cetyl, stearyl, oleyl, behenyl alcohol, cholesterol and 2-hexadecanol;

(h) esters such as cetyl lactanoate, myristyl lactate, cetyl lactate, isopropyl myristate, myristyl myristate, isopropyl palmitate, isopropyl adipate, butyl stearate, decyl oleate, cholesterol isostearate, glycerol monostearate, glycerol stearate, glycerol tristearate, alkyl lactate;

(i) essential oils such as peppermint, jasmine, camphor, white cedar, bark Poncirus trifoliata, ryu, turpentine, cinnamon, bergamot, Citrus unshiu essential oil, cinnamon, pine, lavender, laurel, clove, hibiscus, eucalyptus, citrus, citrus, citrus, , peppermint, pink, sage, menthol, cineol, eugenol, citral, citronel, borneol, linalool, geraniol, evening primrose oil · · • 4 · ·

- 20 4 4 4 4

4 4 4 4

4 · 4 4 biennial, camphor, thymol, spirantole, pinene, limonene and terpenoid oils;

(j) lipids such as cholesterol, ceramides, sucrose esters and pseudoceramides as described in European patent application no. 556,957;

(k) vitamins such as vitamin A and E and alkyl esters of vitamins including vitamin C alkyl esters;

(1) sunscreens such as octylmethoxylcinnamate (Parsol MCX) and butylmethoxyio benzoylmethane (Parsol 1789);

(m) phospholipids; and (n) mixtures of any of the foregoing.

A particularly preferred benefit is silicone, preferably silicones with a viscosity of greater than about 10 Pas. The silicones may be in the form of a rubber and / or may be a mixture of silicones. An example is a polydimethylsiloxane having a viscosity of about 0.06 m ² s ^-1 .

All percentages are by weight unless otherwise indicated.

BRIEF DESCRIPTION OF THE DRAWINGS

Giant. 1 is a graph showing that polyethylene glycol having a molecular weight of 400 or greater substantially reduces the amount of zein dissolved by acyl isethionate (i.e., is less rough) when the PEG isethionate weight ratio is more than 1: 1, preferably more than 2: 1.

Giant. 2 shows that at a molecular weight of less than 400 it does not reduce PEG or other water-soluble nonionic

Monomer (e.g., ethylene glycol, propylene glycol), an amount of zein dissolved by isethionate.

Giant. 3 shows that, at a molecular weight of less than 400, PEG or other water-soluble nonionic monomer does not reduce the amount of zein dissolved by sodium lauryl ether sulfate.

DETAILED DESCRIPTION OF THE INVENTION

Methods

Evaluation of fineness

A zein dissolution test was used for preliminary systematic investigation of the irritant ability of the tested compositions. In a 225 g vessel, 30 ml of an aqueous dispersion of the composition was prepared. The dispersion was placed in a bath of 45 ° C until completely dissolved. After equilibration at room temperature, 1.5 g of zein powder was added to each solution and the mixture was stirred rapidly for one hour. The solutions were then transferred to centrifuge tubes and centrifuged for 30 min at approximately 3000 rpm. The undissolved zein was isolated, rinsed and allowed to dry at 60 ° C in a vacuum oven to constant weight. The percentage of dissolved zein, which is proportional to the irritability, was determined gravimetrically.

Material processing (melt casting)

The cubes were made by casting melt. First, the ingredients were mixed together at 80 to 120 ° C in a 500 ml beaker and the amount of water was adjusted to about 10 to 15% by weight. The beaker was covered to prevent moisture loss and was stirred for an additional 15 minutes. The cover was then removed and the mixture allowed to dry. The moisture content of the samples taken at different time intervals during drying was determined by Karl Fisher titration to

- 21 turbo titrator. At a final moisture content (55% by weight), the mixture in a beaker (as a free-flowing liquid) was dropped into cube molds and allowed to cool at room temperature for four hours. After solidification, the mixture was poured into a cube.

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111 111

1

11

Example 1

Effect of PEG (molecular weight> 300) / anionic surfactant on anionic surfactant-protein interaction

In the Zein Dissolution Test (Figure 1), PEGs of 400 and above have been found to significantly reduce the amount of zein protein dissolved by sodium acyl isethionate when the ratio of PEG to anionic surfactant is greater than 1: 1, preferably greater than 2 : 1. Below the PEG / anionic surfactant ratio of 1: 1, the beneficial effect of PEG on reducing zein dissolution was insignificant. These results show that only at a relatively high content of added PEGs having a molecular weight greater than 300 Daltons, preferably greater than 350 Daltons, do these PEGs act as skin moisturizers reducing the interaction of the surfactant with the skin, leading to skin irritation.

Example 2

Absence of increase in fineness by PEG (molecular weight

300) anionic surfactants

At a molecular weight of 300 and below, PEG and the water-soluble nonionic monomers present (i.e., ethylene glycol, propylene glycol, sorbitol, and glycerol) do not significantly reduce the amount of zein protein dissolved by sodium acyl isethionate (Figure 2) and lauryl ether sulfate (3EO) (Figure 3). Therefore, there is a molecular weight cut-off of PEG (about 300) below which PEG and stated in water

- 22 • 9 9 99 9 9 9 99 99 9499 999 9 * 99 994

999 999 999 9

9 · 99 9 99 • · 9 99 99 99 99 soluble monomers do not reduce protein interaction that may lead to skin irritation surfactantExample 3

Cubes material composition

In Table 1, the compositions of bars 1-4 listed use sodium anionic acyl isethionate and sodium lauryl ether sulfate (3EO) and amphoteric cocamidopropyl betaine as the main detergents. It is novel in the art that these bar materials contain a relatively large amount of low molecular weight PEG (molecular weight between 400 and 1500) as a humectant. PEG 1450 and PEG 1000 in these ultra-fine bars (composition No. 1 to No. 4) promote the formation of a particularly rich and creamy foam.

- 23 Table 1: Composition of cube material containing relatively high low molecular weight PEG contents φφ·· ·φ·······φφφφφφφφφφφφφφφφφφφφφφφφ ·φ · · · · · · · · · · · · · · ·φφ ·· φφφ φφφ φφ φφ φ φφ φφ φφ φφ

Materials No. 1 No. 2 No. 3 No. 4 Ingredients % wt. % wt. % wt. % wt. Sodium acylisethionate 15.0 15.0 8.0 10.0 Lauryl ether sulfate (3EO) sodium 0.0 0.0 2,0 3.0 Kokamidopropylbetain 10.0 10.0 15.0 12.0 Sodium stearate 12.0 15.0 15.0 9.0 PEG 1450 35.5 18.5 40.0 30.0 PEG 1000 0.0 0.0 0.0 12.0 PEG 8000 15.0 29.0 5.0 7.0 Fatty acid 4.0 4.0 9.5 4,5 Paraffin wax 3.0 3.0 0.0 7.0 Water 5.5 5.5 5.5 5.5

Represented by:

Claims (12)

PATENT CLAIMS A detergent composition comprising: (a) 2 to 35% by weight of a synthetic non-soap anionic surfactant; (b) 0 to 20% by weight of an amphoteric, zwitterionic or nonionic surfactant or mixtures thereof; (c) 10 to 70% by weight of polyalkylene glycols having a molecular weight greater than 300 to about 1500; the weight ratio of component (c) to (a) is greater than 1: 1; (d) more than about 1 to 20% by weight of gelling agents; (e) 2% to less than 10% by weight of water. A composition according to claim 1 (d), wherein the gelling agents are selected from the group of C ₈ to C 25 neutralized carboxylic acids (soaps), paraffin waxes, polyethylene waxes, glyceryl stearate, petroleum jelly, fats, jellies, amorphous oxide silica, aluminosilicates, urea, clay and mixtures thereof. A composition according to claim 1, characterized in that it contains 0 to 35% by weight of solid structurants and fillers selected from the group of C ₈ to C ₂₈ fatty acids, C ₈ to C ₂₀ alkanols, water-soluble starches (ie maltodextrin) , polyalkylene glycol having a molecular weight between 2500 and 10,000 and mixtures thereof. ? Κ / 3Η BBBB bb ~ · ·· ·· ·· ·· y _to # • · · · · · β Β «• Β Β Β · Β Β Β Β Β ΒΒΒ ΒΒΒ ΒΒΒ · · · · · · · · · · · · · - 25 The composition of claim 1 (c), wherein the weight ratio of polyalkylene glycol 1 (c) to the anionic surfactant 1 (a) is greater than 2: 1. The composition of claim 1 (a), wherein the synthetic non-soap anionic surfactant comprises 10 to 30% by weight of the total composition. The composition of claim 1 (b), wherein the amphoteric and zwitterionic surfactants comprise from 2 to 15% by weight of the total composition. The composition of claim 1 (c), wherein the low molecular weight polyalkylene glycol has a structure of: R 1 -O (CH ₂ -CHO) _n HI r ₂ where R 1 = H, C ₁ to C ₄ alkyl; R ₂ = H, CH _3; and n is greater than 6 and less than 35. A composition according to claim 2, wherein the neutralized fatty acid (soap) is C ₁₂ - C ₂ 2. - 26 β neutralized straight chain saturated monocarboxylic acid. 9. The composition of claim 3, wherein: Wherein the structurant is a C ₈ to C 25 carboxylic fatty acid and the fatty acid constitutes 5 to 25% by weight of the total composition. 10. The composition of claim 3, Wherein the structurant is a fatty acid and the fatty acid is a straight chained C12 to _C22 monocarboxylic acid. A composition according to claim 3, characterized in that Wherein the alkanol is cetyl alcohol. The composition of claim 1 (c), wherein the polyalkylene glycols have a molecular weight of greater than 350 to about 1500 Daltons.