CY2022038I2 - CYTOTOXIC DIPEPTIDE LYOPHRIZED PREPARATION - Google Patents

CYTOTOXIC DIPEPTIDE LYOPHRIZED PREPARATION

Info

Publication number
CY2022038I2
CY2022038I2 CY2022038C CY2022038C CY2022038I2 CY 2022038 I2 CY2022038 I2 CY 2022038I2 CY 2022038 C CY2022038 C CY 2022038C CY 2022038 C CY2022038 C CY 2022038C CY 2022038 I2 CY2022038 I2 CY 2022038I2
Authority
CY
Cyprus
Prior art keywords
lyophrized
preparation
cytotoxic dipeptide
dipeptide
cytotoxic
Prior art date
Application number
CY2022038C
Other languages
Greek (el)
Other versions
CY2022038I1 (en
Original Assignee
Oncopeptides Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2012/057577 external-priority patent/WO2012146625A1/en
Application filed by Oncopeptides Ab filed Critical Oncopeptides Ab
Publication of CY2022038I2 publication Critical patent/CY2022038I2/en
Publication of CY2022038I1 publication Critical patent/CY2022038I1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • A61K38/105Bombesin; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Mechanical Engineering (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
CY2022038C 2011-04-28 2022-12-22 CYTOTOXIC DIPEPTIDE LYOPHRIZED PREPARATION CY2022038I1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1150371 2011-04-28
US201161535126P 2011-09-15 2011-09-15
PCT/EP2012/057577 WO2012146625A1 (en) 2011-04-28 2012-04-25 Lyophilized preparation of cytotoxic dipeptides

Publications (2)

Publication Number Publication Date
CY2022038I2 true CY2022038I2 (en) 2023-01-27
CY2022038I1 CY2022038I1 (en) 2023-01-27

Family

ID=69569109

Family Applications (1)

Application Number Title Priority Date Filing Date
CY2022038C CY2022038I1 (en) 2011-04-28 2022-12-22 CYTOTOXIC DIPEPTIDE LYOPHRIZED PREPARATION

Country Status (9)

Country Link
KR (2) KR102194376B1 (en)
CY (1) CY2022038I1 (en)
ES (1) ES2813979T3 (en)
HK (1) HK1250492A1 (en)
HR (1) HRP20201300T1 (en)
HU (1) HUE051690T4 (en)
IL (1) IL280812B2 (en)
LT (1) LT3228319T (en)
PT (1) PT3228319T (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021327164A1 (en) * 2020-08-19 2023-03-16 Cellact Pharma Gmbh Etoposide toniribate formulation
KR20220148124A (en) * 2021-04-28 2022-11-04 인천대학교 산학협력단 Lyophilized formulation for extracellular vesicle
EP4233837A1 (en) * 2022-02-24 2023-08-30 CellAct Pharma GmbH Solid and oral etoposide toniribate compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0002202D0 (en) * 2000-06-13 2000-06-13 Karolinska Innovations Ab New peptides
US6992207B2 (en) 2000-06-13 2006-01-31 Oncopeptides Ab Melphalan derivatives and their use as cancer chemotherapeutic drugs
US6780324B2 (en) * 2002-03-18 2004-08-24 Labopharm, Inc. Preparation of sterile stabilized nanodispersions
US20040034099A1 (en) 2002-06-27 2004-02-19 Ramsey Beverly J. Pharmaceutical composition

Also Published As

Publication number Publication date
KR102122429B1 (en) 2020-06-12
LT3228319T (en) 2020-09-25
HK1250492A1 (en) 2018-12-21
KR102194376B1 (en) 2020-12-23
KR20200014947A (en) 2020-02-11
IL280812A (en) 2021-04-29
IL280812B (en) 2022-12-01
CY2022038I1 (en) 2023-01-27
HRP20201300T1 (en) 2020-11-27
ES2813979T3 (en) 2021-03-25
KR20200084890A (en) 2020-07-13
HUE051690T4 (en) 2023-09-28
IL280812B2 (en) 2023-04-01
PT3228319T (en) 2020-08-27
HUE051690T2 (en) 2021-03-29

Similar Documents

Publication Publication Date Title
FR23C1000I2 (en) LYOPHILIZED PREPARATION OF CYTOTOXIC DIPEPTIDES
DK2694038T3 (en) PHARMACEUTICAL COMPOSITION
BR112014003052A2 (en) pharmaceutical compositions
DK2709667T3 (en) BIO-ORTHOGONAL MEDICINE ACTIVATION
BR112014004902A2 (en) peptides
CO6900146A2 (en) Amino substituted imidazopyridazines
BR112014007261A2 (en) pharmaceutical order picker
CO6930367A2 (en) Pharmaceutical compositions
SG10201604667YA (en) Pharmaceutical preparation
CO6940426A2 (en) Pharmaceutical formulations
DK2714004T3 (en) CONTROLLED RELEASE PEPTIDE FORMULATIONS
SMT201600425B (en) PREPARATION FOR COLONSCOPY
EP2767257A4 (en) Articulator
CO6960557A2 (en) 2-iodo-imidazole derivatives
CY2022038I2 (en) CYTOTOXIC DIPEPTIDE LYOPHRIZED PREPARATION
DK3498313T3 (en) TUBULAR DENTURES
BR112014009319A2 (en) pharmaceutical compounds
GB201105298D0 (en) Pharmaceutical preparation
BR112014015885A2 (en) pharmaceutical preparation
BR112014008091A2 (en) Toothbrush
BR112013003504A2 (en) single backrest
FR2975564B1 (en) PLOW
CO6960544A2 (en) Sustained Release Preparation
DK2672817T3 (en) IMPROVED INSECTICID FORMULATIONS
PL2691119T3 (en) Pharmaceutical preparation