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Priority claimed from EP10714094.9Aexternal-prioritypatent/EP2406279B1/en
Application filed by Ramot At Tel-Aviv University Ltd.filedCriticalRamot At Tel-Aviv University Ltd.
Publication of CY1117399T1publicationCriticalpatent/CY1117399T1/en
Medicines That Contain Protein Lipid Enzymes And Other Medicines
(AREA)
Peptides Or Proteins
(AREA)
Abstract
Απομονωμένα πεπτίδια παρέχονται, που έχουν μήκος κάτω από 20 αμινοξέα. Τα πεπτίδια που περιέχουν μια αλληλουχία αμινοξέων GVLYVGSKTREGV (SEQ ID NO: 12) AAATGLVKREE (SEQ ID NO: 13) ή GVVAAAEKTKQG (SEQ ID NO: 14), μιμητές και/ή θραύσματα αυτών, τα οποία πεπτίδια είναι ικανά να αναστέλλουν τη συσσωμάτωση αλφα συνουκλεϊνης. Φαρμακευτικές συνθέσεις που περιέχουν τα ίδια επίσης παρέχονται όπως επίσης και χρήσεις αυτών.Isolated peptides are provided, having a length of less than 20 amino acids. Peptides containing an amino acid sequence GVLYVGSKTREGV (SEQ ID NO: 12) AAATGLVKREE (SEQ ID NO: 13) or GVVAAAEKTKQG (SEQ ID NO: 14), mimics and / or fragments thereof, which peptides are capable of inhibiting of synuclein. Pharmaceutical compositions containing the same are also provided as well as uses thereof.
CY20161100306T2009-03-092016-04-12
COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF NEUROLOGICAL DISEASES
CY1117399T1
(en)