CY1116346T1 - OXIDATIVE ACTIVE THERAPEUTIC SUBSTANCES FOR THE TREATMENT OF MITCHONDICLE DISEASES AND OTHER DISEASES AND FOR THE REGULATION OF BIOLOGICAL INDICATORS - Google Patents

OXIDATIVE ACTIVE THERAPEUTIC SUBSTANCES FOR THE TREATMENT OF MITCHONDICLE DISEASES AND OTHER DISEASES AND FOR THE REGULATION OF BIOLOGICAL INDICATORS

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Publication number
CY1116346T1
CY1116346T1 CY20151100256T CY151100256T CY1116346T1 CY 1116346 T1 CY1116346 T1 CY 1116346T1 CY 20151100256 T CY20151100256 T CY 20151100256T CY 151100256 T CY151100256 T CY 151100256T CY 1116346 T1 CY1116346 T1 CY 1116346T1
Authority
CY
Cyprus
Prior art keywords
diseases
treatment
methods
disclosed
mitchondicle
Prior art date
Application number
CY20151100256T
Other languages
Greek (el)
Inventor
Guy M Miller
Sidney M Hecht
Original Assignee
Edison Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP06784530.5A external-priority patent/EP1888059B1/en
Application filed by Edison Pharmaceuticals, Inc. filed Critical Edison Pharmaceuticals, Inc.
Publication of CY1116346T1 publication Critical patent/CY1116346T1/en

Links

Abstract

Γνωστοποιούνται μέθοδοι για τη θεραπεία ή την καταστολή μιτοχονδριακών νόσων, όπως αταξία του Friedreich (FRDA), Κληρονομική Οπτική Νευροπάθεια του Leber (LHON), μιτοχονδριακή μυοπάθεια, εγκεφαλοπάθεια, γαλακτική οξέωση, εγκεφαλικό επεισόδιο (MELAS) ή Σύνδρομο Kearns-Sayre (KSS), καθώς και ενώσεις χρήσιμες στις μεθόδους της θεραπείας, όπως κινόνη άλφα-τοκοφερόλης. Γνωστοποιούνται επίσης μέθοδοι και ενώσεις χρήσιμες στη θεραπεία άλλων διαταραχών. Γνωστοποιούνται επίσης βιολογικοί δείκτες ενέργειας χρήσιμοι στην αξιολόγηση της μεταβολικής κατάστασης ενός υποκειμένου και της αποτελεσματικότητας της θεραπείας. Γνωστοποιούνται επίσης μέθοδοι ρύθμισης, κανονικοποίησης ή ενίσχυσης των βιολογικών δεικτών ενέργειας, καθώς και ενώσεις χρήσιμες για αυτές τις μεθόδους.Methods for the treatment or suppression of mitochondrial diseases are disclosed, such as Friedreich's Ataxia (FRDA), Leber Hereditary Optic Neuropathy (LHON), Mitochondrial Myopathy, Encephalopathy, Lactic Acid (KAS) Syndrome as well as compounds useful in methods of treatment, such as quinone alpha-tocopherol. Methods and compounds useful in the treatment of other disorders are also disclosed. Biological energy markers useful in assessing a subject's metabolic status and treatment effectiveness are also disclosed. Methods for regulating, normalizing or enhancing biological energy indices as well as compounds useful for these methods are also disclosed.

CY20151100256T 2005-06-01 2015-03-13 OXIDATIVE ACTIVE THERAPEUTIC SUBSTANCES FOR THE TREATMENT OF MITCHONDICLE DISEASES AND OTHER DISEASES AND FOR THE REGULATION OF BIOLOGICAL INDICATORS CY1116346T1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US68682605A 2005-06-01 2005-06-01
US70181505A 2005-07-21 2005-07-21
US77602806A 2006-02-22 2006-02-22
EP06784530.5A EP1888059B1 (en) 2005-06-01 2006-06-01 Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers

Publications (1)

Publication Number Publication Date
CY1116346T1 true CY1116346T1 (en) 2017-02-08

Family

ID=58457927

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20151100256T CY1116346T1 (en) 2005-06-01 2015-03-13 OXIDATIVE ACTIVE THERAPEUTIC SUBSTANCES FOR THE TREATMENT OF MITCHONDICLE DISEASES AND OTHER DISEASES AND FOR THE REGULATION OF BIOLOGICAL INDICATORS

Country Status (1)

Country Link
CY (1) CY1116346T1 (en)

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