CY1116335T1 - PHARMACEUTICAL COMPOSITIONS CONTAINING N- (4 (2-AMINO-3-CHLOROPYRIDIN-4-YLOXY) -3-FLUOROPHYNYL) -4-ETHOXY-L-(4-FYTHO-2-O -YYYL) -CARBOXAMIDE - Google Patents
PHARMACEUTICAL COMPOSITIONS CONTAINING N- (4 (2-AMINO-3-CHLOROPYRIDIN-4-YLOXY) -3-FLUOROPHYNYL) -4-ETHOXY-L-(4-FYTHO-2-O -YYYL) -CARBOXAMIDEInfo
- Publication number
- CY1116335T1 CY1116335T1 CY20151100301T CY151100301T CY1116335T1 CY 1116335 T1 CY1116335 T1 CY 1116335T1 CY 20151100301 T CY20151100301 T CY 20151100301T CY 151100301 T CY151100301 T CY 151100301T CY 1116335 T1 CY1116335 T1 CY 1116335T1
- Authority
- CY
- Cyprus
- Prior art keywords
- chloropyridin
- yloxy
- carboxamide
- ethoxy
- amino
- Prior art date
Links
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Αποκαλύπτονται άλατα και κρυσταλλικές μορφές του Ν-(4-(2-αμινο-3-χλωροπυριδιν-4-υλοξυ)-3-φθοροφαινυλ)-4-αιθοξυ-1-(4-φθοροφαινυλ)-2-οξο-1,2-διϋδροπυριδιν-3-καρβοξαμιδίου και των αλάτων εξ αυτού. Επίσης αποκαλύπτονται μια τουλάχιστον φαρμακευτική σύνθεση που περιλαμβάνει μια τουλάχιστον κρυσταλλική μορφή του Ν-(4-(2-αμινο-3-χλωροπυριδιν-4-υλοξυ)-3-φθοροφαινυλ)-4-αιθοξυ-1-(4-φθοροφαινυλ)-2-οξο-1,2-διϋδροπυριδιν-3-καρβοξαμιδίου, μια τουλάχιστον μέθοδος χρήσης μιας τουλάχιστον κρυσταλλικής μορφής του Ν-(4-(2-αμινο-3-χλωροπυριδιν-4-υλοξυ)-3-φθοροφαινυλ)-4-αιθοξυ-1-(4-φθοροφαινυλ)-2-οξο-1,2-διϋδροπυριδιν-3-καρβοξαμιδίου για την αγωγή του καρκίνου και/ή άλλων υπερπλαστικών παθήσεων, και διεργασίες για την παρασκευή των κρυσταλλικών μορφών του Ν-(4-(2-αμινο-3-χλωροπυριδιν-4-υλοξυ)-3-φθοροφαινυλ)-4-αιθοξυ-1-(4-φθοροφαινυλ)-2-οξο-1,2-διϋδροπυριδιν-3-καρβοξαμιδίου και των αλάτων εξ αυτού.Salts and crystalline forms of N- (4- (2-amino-3-chloropyridin-4-yloxy) -3-fluorophenyl) -4-ethoxy-1- (4-fluorophenyl) -2-oxo-1,2- dihydropyridine-3-carboxamide and the salts thereof. Also disclosed are at least one pharmaceutical composition comprising at least one crystalline form of N- (4- (2-amino-3-chloropyridin-4-yloxy) -3-fluorophenyl) -4-ethoxy-1- (4-fluorophenyl) -2 -oxo-1,2-dihydropyridin-3-carboxamide, at least one method of using at least one crystalline form of N- (4- (2-amino-3-chloropyridin-4-yloxy) -3-fluorophenyl) -4-ethoxy- 1- (4-fluorophenyl) -2-oxo-1,2-dihydropyridin-3-carboxamide for the treatment of cancer and / or other hyperplastic diseases, and processes for the preparation of crystalline forms of N- (4- (2- amino-3 -chloropyridin-4-yloxy) -3-fluorophenyl) -4-ethoxy-1- (4-fluorophenyl) -2-oxo-1,2-dihydropyridin-3-carboxamide and the salts thereof.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32971010A | 2010-04-30 | 2010-04-30 | |
EP11717917.6A EP2563763B1 (en) | 2010-04-30 | 2011-04-29 | Pharmaceutical compositions comprising n-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-l-(4-fluorophenyl)-2-oxo- 1,2-dihydropyridine-3 -carboxamide |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1116335T1 true CY1116335T1 (en) | 2017-02-08 |
Family
ID=58457985
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20151100301T CY1116335T1 (en) | 2010-04-30 | 2015-03-26 | PHARMACEUTICAL COMPOSITIONS CONTAINING N- (4 (2-AMINO-3-CHLOROPYRIDIN-4-YLOXY) -3-FLUOROPHYNYL) -4-ETHOXY-L-(4-FYTHO-2-O -YYYL) -CARBOXAMIDE |
Country Status (1)
Country | Link |
---|---|
CY (1) | CY1116335T1 (en) |
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2015
- 2015-03-26 CY CY20151100301T patent/CY1116335T1/en unknown
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