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Priority claimed from EP07868362.0Aexternal-prioritypatent/EP2069798B1/en
Application filed by Genentech, Inc.filedCriticalGenentech, Inc.
Publication of CY1115197T1publicationCriticalpatent/CY1115197T1/en
Η δραστικότητα αγγειακού ενδοθηλιακού αυξητικού παράγοντα (VEGF) στην κυκλοφορία αίματος ή σε άλλο βιολογικό δείγμα ασθενούς μπορεί να χρησιμεύσει ως διαγνωστικός και προγνωστικός δείκτης για καρκίνο, διαβήτη, καρδιακές παθήσεις, και άλλες παθολογίες. Παρέχονται μέθοδοι και κιτ ELΙSA αντισωμάτων-σάντουιτς για VEGF ως αντιγόνο για ανίχνευση επιπέδων τύπων VEGF σε βιολογικά δείγματα από ζωικά πρότυπα και ανθρώπους ασθενείς και μπορούν να χρησιμοποιηθούν ως διαγνωστικός/προγνωστικός δείκτης.Vascular endothelial growth factor (VEGF) activity in the bloodstream or other biological patient sample can serve as a diagnostic and prognostic marker for cancer, diabetes, heart disease, and other pathologies. Methods and sandwich ELISA antibody kits and kits are provided as antigen for detecting levels of VEGF types in biological samples from animal models and human patients and can be used as a diagnostic / prognostic marker.
pencicillin-binding protein, nucleic acid, antibody or antibody fragment, medicament, pharmaceutical composition, uses of at least one penicillin-binding protein or fragment or variant or fragment thereof, of at least one nucleic acid and of at least one antibody or antibody fragment, in vitro antibody detection methods directed against neisseria meningitidis infection from a penicillin-binding protein, nucleic acid, antibody or an antibody fragment, pharmaceutical composition of at least one penicillin-binding protein or fragment or variant or variant thereof, of at least one nucleic acid and at least one antibody directed against neisseria meningitidis infection from a biological sample of a mammal and in vitro diagnosis of neisseria miningitidis infection from a biological sample from a mammal and monoclonal antibody