CY1115174T1 - A CD44 Monoclonal Antibody FOR USE FOR THE TREATMENT TREATMENT OF BRAIN AND NECK CELL CARCINOMA - Google Patents

A CD44 Monoclonal Antibody FOR USE FOR THE TREATMENT TREATMENT OF BRAIN AND NECK CELL CARCINOMA

Info

Publication number
CY1115174T1
CY1115174T1 CY20141100381T CY141100381T CY1115174T1 CY 1115174 T1 CY1115174 T1 CY 1115174T1 CY 20141100381 T CY20141100381 T CY 20141100381T CY 141100381 T CY141100381 T CY 141100381T CY 1115174 T1 CY1115174 T1 CY 1115174T1
Authority
CY
Cyprus
Prior art keywords
treatment
cell carcinoma
monoclonal antibody
brain
neck cell
Prior art date
Application number
CY20141100381T
Other languages
Greek (el)
Inventor
Cruz Luis Ag Da
Elizabeth Jane Franzmann
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP11703182.3A external-priority patent/EP2531527B1/en
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of CY1115174T1 publication Critical patent/CY1115174T1/en

Links

Abstract

Ένα μονοκλωνικό αντι-CD44 αντίσωμα, ή θραύσμα αυτού πρόσδεσης αντιγόνου, για χρήση για την θεραπευτική αντιμετώπιση ενός καρκινώματος εκ πλακωδών κυττάρων της κεφαλής και του τραχήλου (HNSCC) σε ένα θηλαστικό, όπου το εν λόγω HNSCC χαρακτηρίζεται από την έκφραση της CD44. Το εν λόγω μονοκλωνικό αντίσωμα μπορεί να παραχθεί από το υβρίδωμα το κατατεθημένο στην ATCC με αριθμό εισαγωγής ΡΤΑ-4621 και μπορεί να είναι χιμαιρική ή εξανθρωποποιημένη παραλλαγή αυτού.A monoclonal anti-CD44 antibody, or fragment thereof, for antigen binding, for use in the treatment of a head and neck squamous cell carcinoma (HNSCC) in a mammal, wherein said HNSCC is characterized by CD44 expression. Said monoclonal antibody may be produced from the hybridoma deposited with ATCC with accession number PTA-4621 and may be a chimeric or humanized variant thereof.

CY20141100381T 2010-02-04 2014-05-28 A CD44 Monoclonal Antibody FOR USE FOR THE TREATMENT TREATMENT OF BRAIN AND NECK CELL CARCINOMA CY1115174T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30144910A 2010-02-04 2010-02-04
EP11703182.3A EP2531527B1 (en) 2010-02-04 2011-02-02 A monoclonal antibody to cd44 for use in the treatment of head and neck squamous cell carcinoma

Publications (1)

Publication Number Publication Date
CY1115174T1 true CY1115174T1 (en) 2016-12-14

Family

ID=58464062

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20141100381T CY1115174T1 (en) 2010-02-04 2014-05-28 A CD44 Monoclonal Antibody FOR USE FOR THE TREATMENT TREATMENT OF BRAIN AND NECK CELL CARCINOMA

Country Status (1)

Country Link
CY (1) CY1115174T1 (en)

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