CY1115143T1 -
CRYSTALS CONTAINING APPROPRIATE SALT OF N- [2- (DIETHYLAMINE) SAME] -5 - [(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-indol-3-indol-3-indol) DIMETHYL-1H-PYRROLO-3-CARBOXAMIDE, PREPARATION PROCEDURES FOR THESE AND THEIR COMPOSITIONS
- Google Patents
CRYSTALS CONTAINING APPROPRIATE SALT OF N- [2- (DIETHYLAMINE) SAME] -5 - [(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-indol-3-indol-3-indol) DIMETHYL-1H-PYRROLO-3-CARBOXAMIDE, PREPARATION PROCEDURES FOR THESE AND THEIR COMPOSITIONS
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Priority claimed from EP02759342.5Aexternal-prioritypatent/EP1419151B1/en
Application filed by Pharmacia & Upjohn Company LlcfiledCriticalPharmacia & Upjohn Company Llc
Publication of CY1115143T1publicationCriticalpatent/CY1115143T1/en
Η παρούσα εφεύρεση παρέχει κρυστάλλους, και συνθέσεις αυτών, όπου οι κρύσταλλοι περιλαμβάνουν ένα μηλικό άλας του Ν-[2-(διαιθυλαμινο)αιθυλο]-5-[(5-φθορο-1,2-διϋδρο-2-οξο-3Η-ινδολ-3-ιλιδενο)μεθυλο]-2,4-διμεθυλο-1Η-πυρρολο-3-καρβοξαμιδιου. Επίσης φέρονται στο προσκήνιο μέθοδοι παρασκευής τέτοιων κρυστάλλων.The present invention provides crystals, and compositions thereof, wherein the crystals comprise a maleic salt of N- [2- (diethylamino) ethyl] -5 - [(5-fluoro-1,2-dihydro-2-oxo-3H-indole) -3-ilideno) methyl] -2,4-dimethyl-1H-pyrrolo-3-carboxamide. Methods for preparing such crystals are also brought to the fore.
CY20141100219T2001-08-152014-03-21
CRYSTALS CONTAINING APPROPRIATE SALT OF N- [2- (DIETHYLAMINE) SAME] -5 - [(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-indol-3-indol-3-indol) DIMETHYL-1H-PYRROLO-3-CARBOXAMIDE, PREPARATION PROCEDURES FOR THESE AND THEIR COMPOSITIONS
CY1115143T1
(en)
Chrystals including a malic acid salt of n-[2-(diethylamino)ethyl] -5-[(5-fluoro-1,2-dihydro-2-oxo-3h-indole-3-ylidene)methyl] -2,4-dimethyl-1h-pyrrole-3-carboxamide, processes for its preparation and compositions thereof
CRYSTALS CONTAINING APPROPRIATE SALT OF N- [2- (DIETHYLAMINE) SAME] -5 - [(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-indol-3-indol-3-indol) DIMETHYL-1H-PYRROLO-3-CARBOXAMIDE, PREPARATION PROCEDURES FOR THESE AND THEIR COMPOSITIONS
Crystals containing malic acid salt of N- [2- (diethylamino) ethyl] -5 - [(5-fluoro-2-oxo-3H-indol-3-ylidene) methyl] -2,4-dimethyl-1H-pyrrol-3 -carbonoxamide, its production methods and their chemical formulations
CRYSTALS CONTAINING APPROPRIATE SALT OF N- [2- (DIETHYLAMINE) SAME] -5 - [(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-indol-3-indol-3-indol) DIMETHYL-1H-PYRROLO-3-CARBOXAMIDE, PREPARATION PROCEDURES FOR THESE AND THEIR COMPOSITIONS