CY1114726T1 - TRP-P8 SMALL-MOTOR ACTIVITY REGULATORS - Google Patents
TRP-P8 SMALL-MOTOR ACTIVITY REGULATORSInfo
- Publication number
- CY1114726T1 CY1114726T1 CY20131101155T CY131101155T CY1114726T1 CY 1114726 T1 CY1114726 T1 CY 1114726T1 CY 20131101155 T CY20131101155 T CY 20131101155T CY 131101155 T CY131101155 T CY 131101155T CY 1114726 T1 CY1114726 T1 CY 1114726T1
- Authority
- CY
- Cyprus
- Prior art keywords
- trp
- methods
- small molecule
- small
- motor activity
- Prior art date
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Παρεχόμενοι είναι μικρού-μορίου Τrp-p8 ρυθμιστές που συμπεριλαμβάνουν αγωνιστές Τrp-p8 και ανταγωνιστές Τrp-p8 και συνθέσεις που περιλαμβάνουν μικρού μορίου αγωνιστές Τrp-p8, καθώς επίσης μέθοδοι για πιστοποίηση και χαρακτηρισμό νέων μικρού-μορίου ρυθμιστών Τrp-p8 και μεθόδους για μείωση βιωσιμότητας ή/και παρεμπόδιση ανάπτυξης των κυττάρων που εκφράζουν Τrp-p8, μεθόδους ενεργοποίησης προκαλούμενης από Τrp-p8 εισροής κατιόντος, μέθοδοι για διέγερση απόπτωσης ή/και νέκρωσης και σχετικές μέθοδοι για τη θεραπεία ασθενειών που συμπεριλαμβάνουν καρκίνους, όπως καρκίνους πνεύμονα, μαστού, κόλου ή/και προστάτη, καθώς επίσης άλλες ασθένειες, όπως καλοήθη προστατική υπερπλασία που συνδυάζονται με έκφραση Τrp-p8.Provided are Trp-p8 small molecule regulators including Trp-p8 agonists and Trp-p8 antagonists, and compositions comprising Trp-p8 small molecule agonists, as well as methods for identifying and characterizing novel Trp-p8 small molecule regulators and methods for reduction. viability and / or inhibition of Trp-p8-expressing cells, Trp-p8-mediated activation methods, methods for stimulating apoptosis and / or necrosis, and related methods for the treatment of diseases including cancer such as lung, breast, colon and / or prostate cancers, as well as other diseases, such as benign prostatic hyperplasia associated with expression of Trp-p8.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77343506A | 2006-02-15 | 2006-02-15 | |
EP07750861.2A EP1986622B1 (en) | 2006-02-15 | 2007-02-15 | Small-molecule modulators of trp-p8 activity |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1114726T1 true CY1114726T1 (en) | 2017-01-25 |
Family
ID=58456990
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20131101155T CY1114726T1 (en) | 2006-02-15 | 2013-12-20 | TRP-P8 SMALL-MOTOR ACTIVITY REGULATORS |
Country Status (1)
Country | Link |
---|---|
CY (1) | CY1114726T1 (en) |
-
2013
- 2013-12-20 CY CY20131101155T patent/CY1114726T1/en unknown
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