CY1114585T1 - CATALOGS OF A MDR P-Glycoprotein homologue upstream of chromosome 7p15-21 and their uses - Google Patents
CATALOGS OF A MDR P-Glycoprotein homologue upstream of chromosome 7p15-21 and their usesInfo
- Publication number
- CY1114585T1 CY1114585T1 CY20131100987T CY131100987T CY1114585T1 CY 1114585 T1 CY1114585 T1 CY 1114585T1 CY 20131100987 T CY20131100987 T CY 20131100987T CY 131100987 T CY131100987 T CY 131100987T CY 1114585 T1 CY1114585 T1 CY 1114585T1
- Authority
- CY
- Cyprus
- Prior art keywords
- glycoprotein
- mdr
- chromosome
- catalogs
- upstream
- Prior art date
Links
Abstract
Η εφεύρεση αναφέρεται σε μία Ρ-γλυκοπρωτεΐνη της οικογένειας ΜDR που βρίσκεται πάνω στο ανθρώπινο χρωμόσωμα 7p15-21, πολυνουκλεοτιδικές αλληλουχίες που κωδικοποιούν αυτή την Ρ-γλυκοπρωτεΐνη και θραύσματα αυτών. Αυτό το γονίδιο χρησιμοποιείται σε μεθόδους για τον προσδιορισμό της ευπάθειας των καρκινοκυττάρων σε θεραπείες κατευθυνόμενες ενάντια στην αντίσταση σε πολλά φάρμακα, και για το σχεδιασμό διαγνωστικών και θεραπευτικών μεθόδων που σχετίζονται με την αντίσταση σε πολλά φάρμακα για τον καρκίνο. Η εφεύρεση αναφέρεται επίσης σε μεθόδους για τον προσδιορισμό του κατά πόσον μία δοκιμαστική ένωση μπορεί ν' αναστείλει την ανθεκτικότητα απέναντι σε πολλά φάρμακα.The invention relates to a P-glycoprotein of the MDR family located on human chromosome 7p15-21, polynucleotide sequences encoding this P-glycoprotein and fragments thereof. This gene is used in methods to determine the susceptibility of cancer cells to resistance-directed therapies in many drugs, and to design diagnostic and therapeutic methods related to resistance to many drugs for cancer. The invention also relates to methods for determining whether a test compound can inhibit resistance to many drugs.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20891300A | 2000-06-05 | 2000-06-05 | |
| EP10151972.6A EP2230253B1 (en) | 2000-06-05 | 2001-06-05 | Antibodies against a homologue of the MDR p-glycoprotein on chromosome 7p15-21 and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1114585T1 true CY1114585T1 (en) | 2016-10-05 |
Family
ID=58448798
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20131100987T CY1114585T1 (en) | 2000-06-05 | 2013-11-06 | CATALOGS OF A MDR P-Glycoprotein homologue upstream of chromosome 7p15-21 and their uses |
| CY20151100540T CY1116807T1 (en) | 2000-06-05 | 2015-06-24 | A gene coding for a homologue of human P-glycoprotein with resistance to many drugs over 7 hours in color over 15 hours. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20151100540T CY1116807T1 (en) | 2000-06-05 | 2015-06-24 | A gene coding for a homologue of human P-glycoprotein with resistance to many drugs over 7 hours in color over 15 hours. |
Country Status (1)
| Country | Link |
|---|---|
| CY (2) | CY1114585T1 (en) |
-
2013
- 2013-11-06 CY CY20131100987T patent/CY1114585T1/en unknown
-
2015
- 2015-06-24 CY CY20151100540T patent/CY1116807T1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1116807T1 (en) | 2017-03-15 |
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