CY1113732T1 - IMIDAZOLO [2,1-B] THIAZOLOGICAL PRODUCTS AS REGULATORS OF SYRTUIN COMPOUNDS - Google Patents

IMIDAZOLO [2,1-B] THIAZOLOGICAL PRODUCTS AS REGULATORS OF SYRTUIN COMPOUNDS

Info

Publication number
CY1113732T1
CY1113732T1 CY20121101257T CY121101257T CY1113732T1 CY 1113732 T1 CY1113732 T1 CY 1113732T1 CY 20121101257 T CY20121101257 T CY 20121101257T CY 121101257 T CY121101257 T CY 121101257T CY 1113732 T1 CY1113732 T1 CY 1113732T1
Authority
CY
Cyprus
Prior art keywords
disorders
diseases
sirtuin
compounds
thiazological
Prior art date
Application number
CY20121101257T
Other languages
Greek (el)
Inventor
Joseph J Nunes
Jill Milne
Jean Bemis
Roger Xie
Chi B Vu
Pui Yee Ng
Jeremy S Disch
Original Assignee
Sirtris Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP06789431A external-priority patent/EP1910384B1/en
Application filed by Sirtris Pharmaceuticals, Inc. filed Critical Sirtris Pharmaceuticals, Inc.
Publication of CY1113732T1 publication Critical patent/CY1113732T1/en

Links

Abstract

Παρέχονται στο παρόν νέες ρυθμιστικές της σιρτουίνης ενώσεις και μέθοδοι χρήσεις αυτών. Οι ρυθμιστικές της σιρτουίνης ενώσεις μπορεί να χρησιμοποιηθούν για αύξηση της διάρκειας ζωής ενός κυττάρου, και αντιμετώπιση και/ή πρόληψη μιας ευρείας ποικιλίας νόσων και διαταραχών περιλαμβάνοντας, για παράδειγμα, νόσους ή διαταραχές που σχετίζονται με γήρανση ή στρες, διαβήτη, παχυσαρκία, νευροεκφυλιστικές νόσους, καρδιοαγγειακή νόσο, διαταραχές της πήξης του αίματος, φλεγμονή, καρκίνο και/ή ερύθημα καθώς επίσης νόσους ή διαταραχές οι οποίες θα ωφελούνται από αυξημένη μιτοχονδριακή δραστικότητα. Επίσης παρέχονται συνθέσεις οι οποίες περιλαμβάνουν μια ρυθμιστική της σιρτουίνης ένωση σε συνδυασμό με άλλο θεραπευτικό παράγοντα.New sirtuin modulators and methods of their use are provided herein. Sirtuin regulatory compounds can be used to increase the life span of a cell, and to treat and / or prevent a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegeneration, cardiovascular disease, coagulation disorders, inflammation, cancer and / or erythema as well as diseases or disorders that will benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin buffer compound in combination with another therapeutic agent.

CY20121101257T 2005-08-04 2012-12-21 IMIDAZOLO [2,1-B] THIAZOLOGICAL PRODUCTS AS REGULATORS OF SYRTUIN COMPOUNDS CY1113732T1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US70561205A 2005-08-04 2005-08-04
US74178305A 2005-12-02 2005-12-02
US77937006A 2006-03-03 2006-03-03
US79227606A 2006-04-14 2006-04-14
EP06789431A EP1910384B1 (en) 2005-08-04 2006-08-04 Imidazo [2,1-b]thiazole derivatives as sirtuin modulating compounds

Publications (1)

Publication Number Publication Date
CY1113732T1 true CY1113732T1 (en) 2016-06-22

Family

ID=58448839

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20121101257T CY1113732T1 (en) 2005-08-04 2012-12-21 IMIDAZOLO [2,1-B] THIAZOLOGICAL PRODUCTS AS REGULATORS OF SYRTUIN COMPOUNDS

Country Status (1)

Country Link
CY (1) CY1113732T1 (en)

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