CY1113593T1 - IL-1 antagonist preparations - Google Patents
IL-1 antagonist preparationsInfo
- Publication number
- CY1113593T1 CY1113593T1 CY20131100092T CY131100092T CY1113593T1 CY 1113593 T1 CY1113593 T1 CY 1113593T1 CY 20131100092 T CY20131100092 T CY 20131100092T CY 131100092 T CY131100092 T CY 131100092T CY 1113593 T1 CY1113593 T1 CY 1113593T1
- Authority
- CY
- Cyprus
- Prior art keywords
- antagonist
- seq
- lyophilized formulation
- antagonist preparations
- preparations
- Prior art date
Links
Abstract
Παρέχονται σκευάσματα ανταγωνιστή ιντερλευκίνης-1 (IL-1) που περιλαμβάνουν προ-λυοφιλιωμένο σκεύασμα, ανασυστημένο λυοφιλιωμένο σκεύασμα, και σταθερό υγρό σκεύασμα. Κατά προτίμηση, ο ανταγωνιστής IL-1 είναι IL-1 trap αποτελούμενη από διμερές δύο συντηγμένων πρωτεϊνών που έχει αλληλουχία αμινοξέων που επιλέγεται από την ομάδα που αποτελείται από αλληλουχία αρ. (SEQ ID NO:) 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, και 26. Πλέον προτιμότερα, η συντηγμένη πρωτεΐνη έχει την αλληλουχία της αλληλουχίας αρ. 10.Interleukin-1 antagonist (IL-1) formulations are provided which comprise a pre-lyophilized formulation, reconstituted lyophilized formulation, and a stable liquid formulation. Preferably, the IL-1 antagonist is an IL-1 trap consisting of a dimer of two fusion proteins having an amino acid sequence selected from the group consisting of SEQ ID NO: 1. (SEQ ID NO :) 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, and 26. Most preferably, the fusion protein has the sequence SEQ ID NO: 2. 10.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60213704A | 2004-08-17 | 2004-08-17 | |
EP05789252A EP1778723B1 (en) | 2004-08-17 | 2005-08-17 | Il-1 antagonist formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1113593T1 true CY1113593T1 (en) | 2016-06-22 |
Family
ID=58448871
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20131100092T CY1113593T1 (en) | 2004-08-17 | 2013-02-01 | IL-1 antagonist preparations |
Country Status (1)
Country | Link |
---|---|
CY (1) | CY1113593T1 (en) |
-
2013
- 2013-02-01 CY CY20131100092T patent/CY1113593T1/en unknown
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CY1113593T1 (en) | IL-1 antagonist preparations |