CY1112245T1 - HETEROalkyl Linked Pyrimidine Derivatives - Google Patents

HETEROalkyl Linked Pyrimidine Derivatives

Info

Publication number
CY1112245T1
CY1112245T1 CY20101100780T CY101100780T CY1112245T1 CY 1112245 T1 CY1112245 T1 CY 1112245T1 CY 20101100780 T CY20101100780 T CY 20101100780T CY 101100780 T CY101100780 T CY 101100780T CY 1112245 T1 CY1112245 T1 CY 1112245T1
Authority
CY
Cyprus
Prior art keywords
compounds
pyrimidine derivatives
heteroalkyl
linked pyrimidine
heteroalkyl linked
Prior art date
Application number
CY20101100780T
Other languages
Greek (el)
Inventor
Stéphanie Blanchard
Kantharaj Ethirajulu
Cheng Hsia Angeline Lee
Harish Kumar Mysore Nagaraj
Anders Poulsen
Eric T Sun
Yee Ling Evelyn Tan
Ee Ling Teo
Anthony Deodaunia William
Original Assignee
S*Bio Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP06813133A external-priority patent/EP1951730B1/en
Application filed by S*Bio Pte Ltd filed Critical S*Bio Pte Ltd
Publication of CY1112245T1 publication Critical patent/CY1112245T1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06Peri-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/16Peri-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D515/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D515/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D515/16Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Η παρούσα εφεύρεση αφορά ενώσεις πυριμιδίνης που είναι χρήσιμες ως αντι-πολλαπλασιαστικοί παράγοντες. Ειδικότερα, η παρούσα εφεύρεση αφορά ετεροαλκύλ συνδεδεμένες και υποκατεστημένες ενώσεις πυριμιδίνης, μεθόδους για την παρασκευή αυτών, φαρμακευτικές συνθέσεις που περιέχουν τις ενώσεις αυτές και χρήσεις αυτών των ενώσεων στην θεραπεία πολλαπλασιαστικών διαταραχών. Αυτές οι ενώσεις μπορεί να είναι χρήσιμες ως φάρμακα για την θεραπεία αριθμού πολλαπλασιαστικών διαταραχών που συμπεριλαμβάνουν όγκους και καρκίνους, καθώς επίσης άλλων καταστάσεων ή διαταραχών που συνδυάζονται με κινάσες.The present invention relates to pyrimidine compounds useful as anti-proliferative agents. In particular, the present invention relates to heteroalkyl linked and substituted pyrimidine compounds, methods for their preparation, pharmaceutical compositions containing these compounds, and uses of these compounds in the treatment of proliferative disorders. These compounds may be useful as medicaments for the treatment of a number of proliferative disorders including tumors and cancers, as well as other conditions or disorders associated with kinases.

CY20101100780T 2005-11-16 2010-08-23 HETEROalkyl Linked Pyrimidine Derivatives CY1112245T1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US73683805P 2005-11-16 2005-11-16
US81733906P 2006-06-30 2006-06-30
US85128306P 2006-10-13 2006-10-13
EP06813133A EP1951730B1 (en) 2005-11-16 2006-11-15 Heteroalkyl linked pyrimidine derivatives

Publications (1)

Publication Number Publication Date
CY1112245T1 true CY1112245T1 (en) 2015-12-09

Family

ID=43034241

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100780T CY1112245T1 (en) 2005-11-16 2010-08-23 HETEROalkyl Linked Pyrimidine Derivatives

Country Status (1)

Country Link
CY (1) CY1112245T1 (en)

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