CY1110467T1 - 2- (OTHER-) ARYLI SUBSTITUTED SUBSTITUTES OF tetrahydroquinoline - Google Patents
2- (OTHER-) ARYLI SUBSTITUTED SUBSTITUTES OF tetrahydroquinolineInfo
- Publication number
- CY1110467T1 CY1110467T1 CY20091100093T CY091100093T CY1110467T1 CY 1110467 T1 CY1110467 T1 CY 1110467T1 CY 20091100093 T CY20091100093 T CY 20091100093T CY 091100093 T CY091100093 T CY 091100093T CY 1110467 T1 CY1110467 T1 CY 1110467T1
- Authority
- CY
- Cyprus
- Prior art keywords
- aryli
- tetrahydroquinoline
- substitutes
- substituted
- substituted substitutes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Abstract
Οι ενώσεις του τύπου όπου τα W, R, R1, R2, R3, R4, R5, R6 και R7 έχουν τις σημασίες που αναφέρονται στην Αξίωση 1, μπορούν να χρησιμοποιηθούν μεταξύ άλλων για την αντιμετώπιση των όγκων.Compounds of the formula wherein W, R, R1, R2, R3, R4, R5, R6 and R7 have the meanings set forth in Claim 1, may be used inter alia to treat tumors.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10360154A DE10360154A1 (en) | 2003-12-20 | 2003-12-20 | New 2-(hetero)aryl-tetrahydroquinoline derivatives and 1,2,3,4-tetrahydro-1,5-naphthyridine derivatives are mitotic motor protein Eg5 inhibitors used as anticancer agents for treating carcinoma or leukemia |
US53996104P | 2004-01-30 | 2004-01-30 | |
DE102004026026A DE102004026026A1 (en) | 2004-05-27 | 2004-05-27 | New 2-(hetero)aryl-tetrahydroquinoline derivatives and 1,2,3,4-tetrahydro-1,5-naphthyridine derivatives are mitotic motor protein Eg5 inhibitors used as anticancer agents for treating carcinoma or leukemia |
EP04803833A EP1761515B1 (en) | 2003-12-20 | 2004-12-14 | 2-(hetero-)aryl substituted tetrahydroquinoline derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1110467T1 true CY1110467T1 (en) | 2015-04-29 |
Family
ID=34743228
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20091100093T CY1110467T1 (en) | 2003-12-20 | 2009-01-27 | 2- (OTHER-) ARYLI SUBSTITUTED SUBSTITUTES OF tetrahydroquinoline |
CY20111100701T CY1111704T1 (en) | 2003-12-20 | 2011-07-19 | TYPES OF PYRANO-KINOLIN TETHYDRATE |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20111100701T CY1111704T1 (en) | 2003-12-20 | 2011-07-19 | TYPES OF PYRANO-KINOLIN TETHYDRATE |
Country Status (6)
Country | Link |
---|---|
KR (1) | KR101211973B1 (en) |
AR (1) | AR047068A1 (en) |
CY (2) | CY1110467T1 (en) |
DE (1) | DE502004008434D1 (en) |
HK (1) | HK1096395A1 (en) |
MX (1) | MXPA06006714A (en) |
-
2004
- 2004-12-14 MX MXPA06006714A patent/MXPA06006714A/en active IP Right Grant
- 2004-12-14 DE DE502004008434T patent/DE502004008434D1/en active Active
- 2004-12-20 AR ARP040104789A patent/AR047068A1/en not_active Application Discontinuation
-
2006
- 2006-06-19 KR KR1020067012117A patent/KR101211973B1/en not_active IP Right Cessation
-
2007
- 2007-04-03 HK HK07103564.3A patent/HK1096395A1/en not_active IP Right Cessation
-
2009
- 2009-01-27 CY CY20091100093T patent/CY1110467T1/en unknown
-
2011
- 2011-07-19 CY CY20111100701T patent/CY1111704T1/en unknown
Also Published As
Publication number | Publication date |
---|---|
MXPA06006714A (en) | 2006-08-18 |
KR20060127002A (en) | 2006-12-11 |
DE502004008434D1 (en) | 2008-12-18 |
AR047068A1 (en) | 2006-01-04 |
KR101211973B1 (en) | 2012-12-13 |
HK1096395A1 (en) | 2007-06-01 |
CY1111704T1 (en) | 2015-10-07 |
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