CY1108790T1 - COMPOSITIONS FOR TREATMENT AND DIAGNOSIS OF OVARIAN CANCER - Google Patents

COMPOSITIONS FOR TREATMENT AND DIAGNOSIS OF OVARIAN CANCER

Info

Publication number
CY1108790T1
CY1108790T1 CY20081101495T CY081101495T CY1108790T1 CY 1108790 T1 CY1108790 T1 CY 1108790T1 CY 20081101495 T CY20081101495 T CY 20081101495T CY 081101495 T CY081101495 T CY 081101495T CY 1108790 T1 CY1108790 T1 CY 1108790T1
Authority
CY
Cyprus
Prior art keywords
compositions
ovarian cancer
diagnosis
treatment
ovarian
Prior art date
Application number
CY20081101495T
Other languages
Greek (el)
Inventor
Jennifer L Mitcham
Gordon E King
Paul Algate
Steven P Fling
Marc W Retter
Gary Richard Fanger
Steven G Reed
Thomas S Vedvick
Darrick Carter
Paul Hill
Earl Albone
Original Assignee
Corixa Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/636,801 external-priority patent/US7202334B1/en
Priority claimed from US09/667,857 external-priority patent/US6699664B1/en
Priority claimed from US09/827,271 external-priority patent/US6962980B2/en
Priority claimed from US09/884,441 external-priority patent/US20020119158A1/en
Application filed by Corixa Corporation filed Critical Corixa Corporation
Publication of CY1108790T1 publication Critical patent/CY1108790T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70532—B7 molecules, e.g. CD80, CD86
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57449—Specifically defined cancers of ovaries
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Αποκαλύπτονται συνθέσεις και μέθοδοι για την θεραπεία και διάγνωση καρκίνου, όπως ωοθηκικού καρκίνου. Οι συνθέσεις μπορεί να περιλαμβάνουν μία ή περισσότερες πρωτεΐνες ωοθηκικού καρκινώματος, ανοσογόνα τμήματα αυτών, πολυνουκλεοτίδια που κωδικοποιούν αυτά τα τμήματα ή αντισώματα ή κύτταρα ανοσοσυστήματος ειδικά γι' αυτές τις πρωτεΐνες. Αυτές οι συνθέσεις μπορούν να χρησιμοποιηθούν, για παράδειγμα, για την πρόληψη και θεραπευτική αγωγή ασθενειών όπως ωοθηκικός καρκίνος. Επιπλέον, παρέχονται μέθοδοι για ταυτοποίηση νεοπλασματικών αντιγόνων που εκκρίνονται από ωοθηκικά καρκινώματα και/ή άλλους όγκους. Πολυπεπτίδια και πολυνουκλεοτίδια όπως παρέχονται εδώ μπορεί επιπλέον να χρησιμοποιηθούν για την διάγνωση και παρακολούθηση ωοθηκικού καρκίνου.Compositions and methods for the treatment and diagnosis of cancer, such as ovarian cancer, are disclosed. The compositions may comprise one or more ovarian carcinoma proteins, immunogenic fragments thereof, polynucleotides encoding these fragments, or antibodies, or immune system cells specific to these proteins. These compositions can be used, for example, to prevent and treat diseases such as ovarian cancer. In addition, methods are provided for the identification of tumor antigens secreted by ovarian carcinomas and / or other tumors. Polypeptides and polynucleotides as provided herein may additionally be used to diagnose and monitor ovarian cancer.

CY20081101495T 2000-07-17 2008-12-23 COMPOSITIONS FOR TREATMENT AND DIAGNOSIS OF OVARIAN CANCER CY1108790T1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US61774700A 2000-07-17 2000-07-17
US09/636,801 US7202334B1 (en) 1998-12-17 2000-08-10 Compositions and methods for the therapy and diagnosis of ovarian cancer
US09/667,857 US6699664B1 (en) 1998-12-17 2000-09-20 Compositions and methods for the therapy and diagnosis of ovarian cancer
US09/827,271 US6962980B2 (en) 1999-09-24 2001-04-04 Compositions and methods for the therapy and diagnosis of ovarian cancer
US09/884,441 US20020119158A1 (en) 1998-12-17 2001-06-18 Compositions and methods for the therapy and diagnosis of ovarian cancer
EP01954748A EP1349870B1 (en) 2000-07-17 2001-07-17 Compositions for the therapy and diagnosis of ovarian cancer

Publications (1)

Publication Number Publication Date
CY1108790T1 true CY1108790T1 (en) 2014-04-09

Family

ID=46395398

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081101495T CY1108790T1 (en) 2000-07-17 2008-12-23 COMPOSITIONS FOR TREATMENT AND DIAGNOSIS OF OVARIAN CANCER

Country Status (3)

Country Link
JP (1) JP4942906B2 (en)
KR (1) KR100935092B1 (en)
CY (1) CY1108790T1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000012758A1 (en) * 1998-09-02 2000-03-09 Diadexus Llc A novel method of diagnosing, monitoring, staging, imaging and treating various cancers
US6468546B1 (en) * 1998-12-17 2002-10-22 Corixa Corporation Compositions and methods for therapy and diagnosis of ovarian cancer

Also Published As

Publication number Publication date
JP4942906B2 (en) 2012-05-30
JP2004526406A (en) 2004-09-02
KR100935092B1 (en) 2010-01-08
KR20030022293A (en) 2003-03-15

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