CY1108612T1 - NON-THERAPEUTIC COMBINATIONS FOR THE TREATMENT OF TUMORS THAT OVERFLOW GANGLOSSIDES - Google Patents
NON-THERAPEUTIC COMBINATIONS FOR THE TREATMENT OF TUMORS THAT OVERFLOW GANGLOSSIDESInfo
- Publication number
- CY1108612T1 CY1108612T1 CY20081101347T CY081101347T CY1108612T1 CY 1108612 T1 CY1108612 T1 CY 1108612T1 CY 20081101347 T CY20081101347 T CY 20081101347T CY 081101347 T CY081101347 T CY 081101347T CY 1108612 T1 CY1108612 T1 CY 1108612T1
- Authority
- CY
- Cyprus
- Prior art keywords
- tumors
- active agent
- whose main
- main active
- combinations
- Prior art date
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Η παρούσα εφεύρεση αναφέρεται στο πεδίο της ανοσολογίας και ειδικότερα σε ανοσοθεραπευτικούς συνδυασμούς που χρησιμοποιούνται για τον έλεγχο της αναπτύξεως και/ή του κυτταρικού πολλαπλασιασμού των όγκων. Διαμέσου της παρούσας εφευρέσεως παρατηρείται μία θεραπευτική επίδραση έναντι των όγκων μέσω του συνδυασμού ιδιοτυπικών εμβολίων των οποίων ο κύριος δραστικός παράγοντας είναι ένα αντίσωμα κατά της γαγγλιοσίδης (Ab1), με ιδιοτυπικά εμβόλια των οποίων ο κύριος δραστικός παράγοντας είναι ένα αντι-ιδιοτυπικό αντίσωμα (Ab2) που λαμβάνεται έναντι ενός αντισώματος κατά της γαγγλιοσίδης, ή εμβόλια των οποίων ο κύριος δραστικός παράγοντας είναι μία ή περισσότερες γαγγλιοσίδες. Περιγράφονται συνδυασμοί αυτών των εμβολίων που προκαλούν μία συνεργική θεραπευτική επίδραση έναντι των όγκων. Οι αναφερόμενοι συνδυασμοί μπορούν να εφαρμοσθούν σε ασθενείς σε διαφορετικές κλινικές καταστάσεις όγκων που εκφράζουν γαγγλιοσίδες.The present invention relates to the field of immunology, and in particular to the immunotherapeutic combinations used to control tumor growth and / or cell proliferation. Through the present invention a therapeutic effect against tumors is observed by combining idiotypic vaccines whose main active agent is an antibody to ganglioside (Ab1), with idiotypic vaccines whose main active agent is an anti-idiotypic2 obtained against an antibody to ganglioside, or vaccines whose main active agent is one or more gangliosides. Combinations of these vaccines that produce a synergistic therapeutic effect against tumors are described. The aforementioned combinations may be applied to patients in different clinical conditions of tumors expressing gangliosides.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU842001 | 2001-04-06 | ||
| EP02759751A EP1384726B1 (en) | 2001-04-06 | 2002-04-08 | Immunotherapeutic combinations for the treatment of tumours that overexpress gangliosides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1108612T1 true CY1108612T1 (en) | 2014-04-09 |
Family
ID=51520363
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20081101347T CY1108612T1 (en) | 2001-04-06 | 2008-11-24 | NON-THERAPEUTIC COMBINATIONS FOR THE TREATMENT OF TUMORS THAT OVERFLOW GANGLOSSIDES |
Country Status (1)
| Country | Link |
|---|---|
| CY (1) | CY1108612T1 (en) |
-
2008
- 2008-11-24 CY CY20081101347T patent/CY1108612T1/en unknown
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