CU23977B1 - CHEMICAL PEPTIDE OF TRYPANOSOMA CRUZI - Google Patents
CHEMICAL PEPTIDE OF TRYPANOSOMA CRUZIInfo
- Publication number
- CU23977B1 CU23977B1 CU20100016A CU20100016A CU23977B1 CU 23977 B1 CU23977 B1 CU 23977B1 CU 20100016 A CU20100016 A CU 20100016A CU 20100016 A CU20100016 A CU 20100016A CU 23977 B1 CU23977 B1 CU 23977B1
- Authority
- CU
- Cuba
- Prior art keywords
- trypanosoma cruzi
- chimeric
- antigen
- chemical peptide
- synthetic peptide
- Prior art date
Links
- 241000223109 Trypanosoma cruzi Species 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 206010001935 American trypanosomiasis Diseases 0.000 abstract 1
- 208000024699 Chagas disease Diseases 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 108091006116 chimeric peptides Proteins 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 239000007790 solid phase Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Landscapes
- Peptides Or Proteins (AREA)
Abstract
Péptido sintético quimérico obtenido mediante síntesis química en fase sólida, que contiene secuencias inmunodominantes del Trypanosoma cruzi, causante del mal de Chagas. La antigenicidad del péptido quimérico fue superior al de los péptidos monoméricos por separado, además de que puede ser utilizado como antígeno para detectar anticuerpos contra más de una proteína simultáneamente. El péptido sintético quimérico puede ser usado como antígeno en ensayos para la detección de anticuerpos específicos al Trypanosoma cruzi, en la certificación de la sangre de donantes y en la vigilancia epidemiológica.Chimeric synthetic peptide obtained by solid-phase chemical synthesis, which contains immunodominant sequences from Trypanosoma cruzi, which causes Chagas disease. The antigenicity of the chimeric peptide was superior to that of the monomeric peptides separately, in addition to that it can be used as an antigen to detect antibodies against more than one protein simultaneously. The chimeric synthetic peptide can be used as an antigen in assays for the detection of antibodies specific to Trypanosoma cruzi, in the certification of donor blood and in epidemiological surveillance.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20100016A CU23977B1 (en) | 2010-01-28 | 2010-01-28 | CHEMICAL PEPTIDE OF TRYPANOSOMA CRUZI |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20100016A CU23977B1 (en) | 2010-01-28 | 2010-01-28 | CHEMICAL PEPTIDE OF TRYPANOSOMA CRUZI |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CU20100016A7 CU20100016A7 (en) | 2012-06-21 |
| CU23977B1 true CU23977B1 (en) | 2014-01-29 |
Family
ID=46514992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU20100016A CU23977B1 (en) | 2010-01-28 | 2010-01-28 | CHEMICAL PEPTIDE OF TRYPANOSOMA CRUZI |
Country Status (1)
| Country | Link |
|---|---|
| CU (1) | CU23977B1 (en) |
-
2010
- 2010-01-28 CU CU20100016A patent/CU23977B1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CU20100016A7 (en) | 2012-06-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant of patent |