CU23957B1 - DERIVATIVES OF TIAZOLIDIN-2,4-DIONA - Google Patents

DERIVATIVES OF TIAZOLIDIN-2,4-DIONA

Info

Publication number
CU23957B1
CU23957B1 CU2010000265A CU20100265A CU23957B1 CU 23957 B1 CU23957 B1 CU 23957B1 CU 2010000265 A CU2010000265 A CU 2010000265A CU 20100265 A CU20100265 A CU 20100265A CU 23957 B1 CU23957 B1 CU 23957B1
Authority
CU
Cuba
Prior art keywords
pim
relates
tiazolidin
diona
derivatives
Prior art date
Application number
CU2010000265A
Other languages
Spanish (es)
Other versions
CU20100265A7 (en
Inventor
Leslie Dakin
James Edward Dowling
Michelle Lamb
Jon Read
Qibin Su
Xiaolan Zheng
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB2009/050773 external-priority patent/WO2010001169A2/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of CU20100265A7 publication Critical patent/CU20100265A7/en
Publication of CU23957B1 publication Critical patent/CU23957B1/en

Links

Abstract

La invención se refiere a compuestos químicos de fórmula I, y sales de los mismos. En algunas realizaciones, la invención se refiere a inhibidores o moduladores de la actividad o función enzimática de la proteína quinasa PIM-I y/o PIM-2 y/o PIM-3. En otras realizaciones adicionales, la invención se refiere a composiciones farmacéuticas que comprenden compuestos descritos en la presente y su uso en la prevención y tratamiento de afecciones y enfermedades relacionadas con la quinasa PIM, preferiblemente cáncer.The invention relates to chemical compounds of formula I, and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of the enzymatic activity or function of the protein kinase PIM-I and / or PIM-2 and / or PIM-3. In other further embodiments, the invention relates to pharmaceutical compositions comprising compounds described herein and their use in the prevention and treatment of conditions and diseases related to PIM kinase, preferably cancer.

CU2010000265A 2009-06-02 2010-12-29 DERIVATIVES OF TIAZOLIDIN-2,4-DIONA CU23957B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18327809P 2009-06-02 2009-06-02
PCT/GB2009/050773 WO2010001169A2 (en) 2008-07-02 2009-07-02 Chemical compounds 251

Publications (2)

Publication Number Publication Date
CU20100265A7 CU20100265A7 (en) 2011-11-15
CU23957B1 true CU23957B1 (en) 2013-10-29

Family

ID=45000178

Family Applications (1)

Application Number Title Priority Date Filing Date
CU2010000265A CU23957B1 (en) 2009-06-02 2010-12-29 DERIVATIVES OF TIAZOLIDIN-2,4-DIONA

Country Status (1)

Country Link
CU (1) CU23957B1 (en)

Also Published As

Publication number Publication date
CU20100265A7 (en) 2011-11-15

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