CU23909B1 - - Google Patents
Info
- Publication number
- CU23909B1 CU23909B1 CU20100111A CU20100111A CU23909B1 CU 23909 B1 CU23909 B1 CU 23909B1 CU 20100111 A CU20100111 A CU 20100111A CU 20100111 A CU20100111 A CU 20100111A CU 23909 B1 CU23909 B1 CU 23909B1
- Authority
- CU
- Cuba
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102007061766A DE102007061766A1 (en) | 2007-12-20 | 2007-12-20 | New 4-(4-cyano-2-thioaryl)-dihydro-pyrimidinone compounds are human neutrophil elastase inhibitor, useful for the treatment or prevention of e.g. pulmonary arterial hypertonia, acute lung injury and diseases of the cardiovascular system |
PCT/EP2008/010411 WO2009080199A1 (en) | 2007-12-20 | 2008-12-09 | 4-(4-cyano-2-thioaryl)dihydropyrimidinones and use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CU20100111A7 CU20100111A7 (en) | 2011-10-14 |
CU23909B1 true CU23909B1 (en) | 2013-06-28 |
Family
ID=40689663
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CU2010000111A CU20100111A7 (en) | 2007-12-20 | 2010-05-31 | 4- (4-CIANO-2-TIOARIL) DIHYDROPIRIMIDINONES AND ITS USE FOR THE TREATMENT AND PREVENTION OF PULMONARY AND CARDIOVASCULAR DISEASES |
Country Status (3)
Country | Link |
---|---|
CU (1) | CU20100111A7 (en) |
DE (1) | DE102007061766A1 (en) |
UA (1) | UA102238C2 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0908394D0 (en) | 2009-05-15 | 2009-06-24 | Univ Leuven Kath | Novel viral replication inhibitors |
GB0913636D0 (en) * | 2009-08-05 | 2009-09-16 | Univ Leuven Kath | Novel viral replication inhibitors |
CA2817165A1 (en) | 2010-11-15 | 2012-05-24 | Patrick Chaltin | Novel antiviral compounds |
US20140221335A1 (en) | 2013-02-06 | 2014-08-07 | Boehringer Ingelheim International Gmbh | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity |
US9115093B2 (en) | 2013-03-04 | 2015-08-25 | Boehringer Ingelheim International Gmbh | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity |
USRE47493E1 (en) | 2014-02-20 | 2019-07-09 | Boehringer Ingelheim International Gmbh | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity |
US9458113B2 (en) | 2014-07-31 | 2016-10-04 | Boehringer Ingelheim International Gmbh | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity |
US9475779B2 (en) | 2014-07-31 | 2016-10-25 | Boehringer Ingelheim International Gmbh | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity |
US9440930B2 (en) | 2014-07-31 | 2016-09-13 | Boehringer Ingelheim International Gmbh | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity |
US9290457B2 (en) | 2014-07-31 | 2016-03-22 | Boehringer Ingelheim International Gmbh | Substituted dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity |
US9657015B2 (en) | 2014-07-31 | 2017-05-23 | Boehringer Ingelheim International Gmbh | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19834047A1 (en) | 1998-07-29 | 2000-02-03 | Bayer Ag | Substituted pyrazole derivatives |
DE19834044A1 (en) | 1998-07-29 | 2000-02-03 | Bayer Ag | New substituted pyrazole derivatives |
DE19943639A1 (en) | 1999-09-13 | 2001-03-15 | Bayer Ag | Dicarboxylic acid derivatives with novel pharmaceutical properties |
DE19943636A1 (en) | 1999-09-13 | 2001-03-15 | Bayer Ag | Novel dicarboxylic acid derivatives with pharmaceutical properties |
DE19943634A1 (en) | 1999-09-13 | 2001-04-12 | Bayer Ag | Novel dicarboxylic acid derivatives with pharmaceutical properties |
DE19943635A1 (en) | 1999-09-13 | 2001-03-15 | Bayer Ag | Novel aminodicarboxylic acid derivatives with pharmaceutical properties |
AR031176A1 (en) | 2000-11-22 | 2003-09-10 | Bayer Ag | NEW DERIVATIVES OF PIRAZOLPIRIDINA SUBSTITUTED WITH PIRIDINE |
DE10110750A1 (en) | 2001-03-07 | 2002-09-12 | Bayer Ag | Novel aminodicarboxylic acid derivatives with pharmaceutical properties |
DE10110749A1 (en) | 2001-03-07 | 2002-09-12 | Bayer Ag | Substituted aminodicarboxylic acid derivatives |
DE10220570A1 (en) | 2002-05-08 | 2003-11-20 | Bayer Ag | Carbamate-substituted pyrazolopyridines |
AU2003255492A1 (en) | 2002-09-10 | 2004-04-30 | Bayer Healthcare Ag | Heterocyclic derivatives |
PL375647A1 (en) | 2002-09-10 | 2005-12-12 | Bayer Healthcare Ag | Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes |
US7166603B2 (en) | 2003-07-23 | 2007-01-23 | Bristol-Myers Squibb Co. | Dihydropyrimidone inhibitors of calcium channel function |
WO2005082864A1 (en) | 2004-02-26 | 2005-09-09 | Bayer Healthcare Ag | 1,4-diaryl-dihydropyrimidin-2-ones and their use as human neutrophil elastase inhibitors |
US7893073B2 (en) | 2004-02-26 | 2011-02-22 | Bayer Schering Pharma Aktiengesellschaft | Heterocyclic derivatives |
GB0502258D0 (en) | 2005-02-03 | 2005-03-09 | Argenta Discovery Ltd | Compounds and their use |
GB0512940D0 (en) | 2005-06-24 | 2005-08-03 | Argenta Discovery Ltd | Compounds and their use |
GB0520743D0 (en) | 2005-10-12 | 2005-11-23 | Argenta Discovery Ltd | Compounds and their use |
ATE480543T1 (en) | 2006-05-04 | 2010-09-15 | Pulmagen Therapeutics Inflamma | TETRAHYDROPYRROLOPYRIMIDIINDIONE AND THEIR USE AS INHIBITORS OF HUMAN NEUTROPHIL ELASTASE |
-
2007
- 2007-12-20 DE DE102007061766A patent/DE102007061766A1/en not_active Withdrawn
-
2008
- 2008-12-09 UA UAA201009015A patent/UA102238C2/en unknown
-
2010
- 2010-05-31 CU CU2010000111A patent/CU20100111A7/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
UA102238C2 (en) | 2013-06-25 |
CU20100111A7 (en) | 2011-10-14 |
DE102007061766A1 (en) | 2009-06-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN300733702S (zh) | 地板(埃及拼花伊斯法罕(isfahan)) | |
CN300729859S (zh) | 控制杆 | |
CN300726353S (zh) | 电动妇科手术床 | |
CN300726955S (zh) | 包装盒(黄金搭档儿童青少年型) | |
CN300727137S (zh) | 包装袋(开心果园) | |
CN300727311S (zh) | 客车(xmq6800/6858/6900/6996) | |
CN300727537S (zh) | 转换插座 | |
CN300727583S (zh) | Mp3播放器 | |
CN300727703S (zh) | 冷却水循环泵 | |
CN300728009S (zh) | 电梯用液晶显示器 | |
CN300728073S (zh) | 玩具吊桥配件(t550) | |
CN300728420S (zh) | 套玉砂点玻璃片(小鱼片) | |
CN300728620S (zh) | 鞋底 | |
CN300728682S (zh) | 眼镜盒(二) | |
CN300728783S (zh) | 墙纸(44a) | |
CN300728867S (zh) | 椅子(3) | |
CN300728955S (zh) | 酒柜 | |
CN300729758S (zh) | 推车底板 | |
CN300733705S (zh) | 门窗装饰框(3) | |
CN300729957S (zh) | 无触点控制装置 | |
CN300730138S (zh) | 电路板(双回路控制卡) | |
CN300730143S (zh) | 平板电视机壁挂架(wlb672) | |
CN300730200S (zh) | 全数控印标自动切片机(dc-628) | |
CN300730356S (zh) | 瓶贴(米婆婆甜香酒酿原汁) | |
CN300730424S (zh) | 模型(韶山9改型电力机车) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant of patent |