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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
La actual invención se relaciona con los ligandos de la fórmula (I) que prefieren los nuevos subtipos receptores de dopamina D3 y D2: en el que R1 y R2 representan independientemente un sustituyente seleccionado a partir del hidrógeno, alquilo, arilo, cicloalquilo, aroilo, o R1 y R2 pueden formar un anillo heterocíclico con el átomo adyacente de nitrógeno; X representa a un átomo de oxígeno o azufre; n constituye un número entero desde 1 hasta 2 y/o isómeros geométricos y/o estereoisómeros y/o diastereómeros y/o sales y/o hidratos y/o solvatos de los mismos, en los procesos para producir los mismos, en las composiciones farmacéuticas que contengan los mismos y en su empleo en la terapia y/o prevención de una afección que requiera la modulación de los receptores de dopamina. ESPACIO PARA FÓRMULAThe present invention relates to the ligands of the formula (I) that prefer the new dopamine D3 and D2 receptor subtypes: in which R1 and R2 independently represent a substituent selected from hydrogen, alkyl, aryl, cycloalkyl, aroyl, or R1 and R2 can form a heterocyclic ring with the adjacent nitrogen atom; X represents an oxygen or sulfur atom; n constitutes an integer from 1 to 2 and / or geometric isomers and / or stereoisomers and / or diastereomers and / or salts and / or hydrates and / or solvates thereof, in the processes for producing them, in pharmaceutical compositions that contain them and in their use in therapy and / or prevention of a condition that requires the modulation of dopamine receptors. FORMULA SPACE
CU20060024A2006-02-032006-02-03
DERIVATIVES OF (TIO) CARBAMOIL-CICLOHEXANO AS ANTAGONISTS OF THE RECEIVER D3 / D2
CU23563A3
(en)
1,2,4-TRIAZOL HETEROCICLIC DERIVATIVES, BETA 2 ADRENERGIC RECEIVER AGONISTS AND COLINERGIC MUSCARINIC ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEMSELVES AND USES OF THE SAME IN THE TREATMENT OF RESPIRATORY AND INFLATORY AFFECTION.
SUBSTITUTED DERIVATIVES OF 4,5- (SUBSTITUTED-PIRIDIN-3-IL) -1-METHYL-1H-INDOL, ITS PHARMACEUTICALLY ACCEPTABLE SALTS, POLYMORPHOS, ROTÁMEROS, PRO-DRUGS, ANANTIOMERS, HYDRATES, SOLVATOS OF THE SAME AND COMPOSITIONS
FUSIONATED BICYCLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION, THE COMPOSITE TO BE USED AS A MEDICINAL PRODUCT IN THE TREATMENT AND PROFILAXIS OF DISEASES, A PHARMACEUTICAL COMPOSITION AND A SET THAT INCLUDES SEPARATE PACKAGES OF THE COMPOUND AND OF AN INGREDIENT
DERIVATIVES OF PIRIDIL-PROLINAMIDE, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND ITS USE FOR THE TREATMENT OF ANXIETY, DEPRESSION AND DISORDERS OF THE SOUND.