CU20140033A7 - PIRROLOPIRIMIDINE AND PURINE DERIVATIVES - Google Patents

PIRROLOPIRIMIDINE AND PURINE DERIVATIVES

Info

Publication number
CU20140033A7
CU20140033A7 CU2014000033A CU20140033A CU20140033A7 CU 20140033 A7 CU20140033 A7 CU 20140033A7 CU 2014000033 A CU2014000033 A CU 2014000033A CU 20140033 A CU20140033 A CU 20140033A CU 20140033 A7 CU20140033 A7 CU 20140033A7
Authority
CU
Cuba
Prior art keywords
compounds
purine derivatives
pirrolopirimidine
mammals
cell growth
Prior art date
Application number
CU2014000033A
Other languages
Spanish (es)
Inventor
Hengmiao Cheng
Jr Theodore Otto Johnson
John Charles Kath
Kevin Kun-Chin Liu
Elizabeth Ann Lunney
Asako Nagata
Sajiv Krishnan Nai
Simon Paul Planken
Scott Channing Sutton
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/IB2012/054702 external-priority patent/WO2013042006A1/en
Application filed by Pfizer filed Critical Pfizer
Publication of CU20140033A7 publication Critical patent/CU20140033A7/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a compuestos de la Fórmula ( I) O sales de estos aceptables desde el punto de vista farmacéutico, en donde Q, T, V, W, X, Y, Z, el anillo A, R^1, R^2, R^3, R^4, R^5, R^6, R^7, R^8, R^9, R^10, R^11, R^12, R^13, R^14, R^15, R^16, R^17 y m se definen en la presente. Los derivados de pirrolopirimidina y purina novedosos son útiles para tratar el crecimiento celular anormal, tal como cáncer, en mamíferos. Otras formas de realización se refieren a composiciones farmacéuticas que contienen los compuestos y a métodos para usar los compuestos y las composiciones en el tratamiento del crecimiento celular anormal en mamíferos.The present invention relates to compounds of the Formula (I) OR pharmaceutically acceptable salts thereof, wherein Q, T, V, W, X, Y, Z, ring A, R ^ 1, R ^ 2, R ^ 3, R ^ 4, R ^ 5, R ^ 6, R ^ 7, R ^ 8, R ^ 9, R ^ 10, R ^ 11, R ^ 12, R ^ 13, R ^ 14 , R ^ 15, R ^ 16, R ^ 17 and m are defined herein. The novel pyrrolopyrimidine and purine derivatives are useful for treating abnormal cell growth, such as cancer, in mammals. Other embodiments relate to pharmaceutical compositions containing the compounds and to methods for using the compounds and compositions in the treatment of abnormal cell growth in mammals.

CU2014000033A 2012-04-27 2014-03-20 PIRROLOPIRIMIDINE AND PURINE DERIVATIVES CU20140033A7 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261639639P 2012-04-27 2012-04-27
PCT/IB2012/054702 WO2013042006A1 (en) 2011-09-22 2012-09-10 Pyrrolopyrimidine and purine derivatives

Publications (1)

Publication Number Publication Date
CU20140033A7 true CU20140033A7 (en) 2014-05-27

Family

ID=52394769

Family Applications (1)

Application Number Title Priority Date Filing Date
CU2014000033A CU20140033A7 (en) 2012-04-27 2014-03-20 PIRROLOPIRIMIDINE AND PURINE DERIVATIVES

Country Status (1)

Country Link
CU (1) CU20140033A7 (en)

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